{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T13:42:37Z","timestamp":1773150157729,"version":"3.50.1"},"reference-count":36,"publisher":"Microbiology Society","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,7,1]]},"DOI":"10.1099\/mic.0.2008\/017566-0","type":"journal-article","created":{"date-parts":[[2008,10,15]],"date-time":"2008-10-15T16:13:46Z","timestamp":1224087226000},"page":"2131-2138","source":"Crossref","is-referenced-by-count":17,"title":["Induction of innate immunity by lipid A mimetics increases survival from pneumonic plague"],"prefix":"10.1099","volume":"154","author":[{"given":"Christina L.","family":"Airhart","sequence":"first","affiliation":[{"name":"Department of Microbiology, Molecular Biology, and Biochemistry, University of Idaho, Moscow, ID 83844-3052, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harold N.","family":"Rohde","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Molecular Biology, and Biochemistry, University of Idaho, Moscow, ID 83844-3052, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregory A.","family":"Bohach","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Molecular Biology, and Biochemistry, University of Idaho, Moscow, ID 83844-3052, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolyn J.","family":"Hovde","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Molecular Biology, and Biochemistry, University of Idaho, Moscow, ID 83844-3052, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia F.","family":"Deobald","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Molecular Biology, and Biochemistry, University of Idaho, Moscow, ID 83844-3052, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen S.","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Statistics, University of Idaho, Moscow, ID 83844-3052, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott A.","family":"Minnich","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Molecular Biology, and Biochemistry, University of Idaho, Moscow, ID 83844-3052, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"345","reference":[{"key":"R1","doi-asserted-by":"crossref","first-page":"4580","DOI":"10.1128\/IAI.64.11.4580-4585.1996","article-title":"Recombinant V antigen protects mice against pneumonic plague and bubonic plague caused by F1-capsule positive and -negative strains of Yersinia pestis","volume":"64","author":"Anderson","year":"1996","journal-title":"Infect Immun"},{"key":"R2","doi-asserted-by":"crossref","first-page":"2180","DOI":"10.1128\/IAI.64.6.2180-2187.1996","article-title":"Fraction 1 capsular antigen (F1) purification from Yersinia pestis CO92 and from an Escherichia coli recombinant strain and efficacy against lethal plague challenge","volume":"64","author":"Andrews","year":"1996","journal-title":"Infect Immun"},{"key":"R3","doi-asserted-by":"crossref","first-page":"3673","DOI":"10.1128\/IAI.71.7.3673-3681.2003","article-title":"Interleukin-10 and inhibition of innate immunity to yersiniae: roles of Yops and LcrV (V-antigen","volume":"71","author":"Brubaker","year":"2003","journal-title":"Infect Immun"},{"key":"R4","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0300-9084(03)00005-1","article-title":"Lipopolysaccharides of bacterial pathogens from the genus Yersinia: a mini-review","volume":"85","author":"Bruneteau","year":"2003","journal-title":"Biochimie"},{"key":"R5","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1128\/AAC.42.3.675","article-title":"Antibiotic treatment of experimental pneumonic plague in mice","volume":"42","author":"Byrne","year":"1998","journal-title":"Antimicrob Agents Chemother"},{"key":"R6","doi-asserted-by":"crossref","first-page":"3044","DOI":"10.1128\/IAI.73.5.3044-3052.2005","article-title":"Synthetic Toll-like receptor 4 agonists stimulate innate resistance to infectious challenge","volume":"73","author":"Cluff","year":"2005","journal-title":"Infect Immun"},{"key":"R7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000107614","article-title":"Isoflurane inhalation after induction of endotoxemia in rats attenuates the systemic cytokine response","volume":"40","author":"Flondor","year":"2007","journal-title":"Eur Surg Res"},{"key":"R8","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1093\/jac\/dkg363","article-title":"Susceptibility of Yersinia pestis to novel and conventional antimicrobial agents","volume":"52","author":"Frean","year":"2003","journal-title":"J Antimicrob Chemother"},{"key":"R9","doi-asserted-by":"crossref","first-page":"1656","DOI":"10.1084\/jem.160.6.1656","article-title":"Priming of neutrophils for enhanced release of oxygen metabolites by bacterial lipolysaccharide. Evidence for increased activity of the superoxide-producing enzyme","volume":"160","author":"Guthrie","year":"1984","journal-title":"J Exp Med"},{"key":"R10","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1086\/520547","article-title":"Comparison of 2 antibiotics that inhibit protein synthesis for the treatment of infection with Yersinia pestis delivered by aerosol in a mouse model of pneumonic plague","volume":"196","author":"Heine","year":"2007","journal-title":"J Infect Dis"},{"key":"R11","doi-asserted-by":"crossref","first-page":"6676","DOI":"10.1128\/IAI.72.11.6676-6679.2004","article-title":"Mucosal administration of flagellin induces innate immunity in the mouse lung","volume":"72","author":"Honko","year":"2004","journal-title":"Infect Immun"},{"key":"R12","doi-asserted-by":"crossref","first-page":"2281","DOI":"10.1001\/jama.283.17.2281","article-title":"Plague as a biological weapon: medical and public health management","volume":"283","author":"Inglesby","year":"2000","journal-title":"JAMA"},{"key":"R13","doi-asserted-by":"crossref","DOI":"10.1128\/9781555817671","volume-title":"The Innate Immune Response to Infection","author":"Kaufman","year":"2004"},{"key":"R14","doi-asserted-by":"crossref","first-page":"17786","DOI":"10.1073\/pnas.0506840102","article-title":"Progression of primary pneumonic plague: a mouse model of infection, pathology, and bacterial transcriptional activity","volume":"102","author":"Lathem","year":"2005","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R15","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1126\/science.1137195","article-title":"A plasminogen-activating protease specifically controls the development of primary pneumonic plague","volume":"315","author":"Lathem","year":"2007","journal-title":"Science"},{"key":"R16","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1006\/mpat.1997.0141","article-title":"Expression of an F1\/V fusion protein in attenuated Salmonella typhimurium and protection of mice against plague","volume":"23","author":"Leary","year":"1997","journal-title":"Microb Pathog"},{"key":"R17","doi-asserted-by":"crossref","first-page":"2498","DOI":"10.1128\/IAI.71.5.2498-2507.2003","article-title":"Role of innate immune factors in the adjuvant activity of monophosphoryl lipid A","volume":"71","author":"Martin","year":"2003","journal-title":"Infect Immun"},{"key":"R18","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1007\/978-0-387-72124-8_27","article-title":"A rationale for repression and\/or loss of motility by pathogenic Yersinia in the mammalian host","volume":"603","author":"Minnich","year":"2007","journal-title":"Adv Exp Med Biol"},{"key":"R19","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1038\/ni1386","article-title":"Virulence factors of Yersinia pestis are overcome by a strong lipopolysaccharide response","volume":"7","author":"Montminy","year":"2006","journal-title":"Nat Immunol"},{"key":"R20","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1111\/j.1365-2567.2004.01941.x","article-title":"The potential for Toll-like receptors to collaborate with other innate immune receptors","volume":"112","author":"Mukhopadhyay","year":"2004","journal-title":"Immunology"},{"key":"R21","doi-asserted-by":"crossref","first-page":"5152","DOI":"10.1128\/IAI.73.8.5152-5159.2005","article-title":"LcrV plague vaccine with altered immunomodulatory properties","volume":"73","author":"Overheim","year":"2005","journal-title":"Infect Immun"},{"key":"R22","doi-asserted-by":"crossref","first-page":"4513","DOI":"10.1128\/AAC.48.12.4513-4519.2004","article-title":"Intranasal interleukin-12 treatment promotes antimicrobial clearance and survival in pulmonary Francisella tularensis subsp. novicida infection","volume":"48","author":"Pammit","year":"2004","journal-title":"Antimicrob Agents Chemother"},{"key":"R23","doi-asserted-by":"crossref","first-page":"3381","DOI":"10.1128\/IAI.00185-06","article-title":"Gamma interferon, tumor necrosis factor alpha, and nitric oxide synthase 2, key elements of cellular immunity, perform critical protective functions during humoral defense against lethal pulmonary Yersinia pestis infection","volume":"74","author":"Parent","year":"2006","journal-title":"Infect Immun"},{"key":"R24","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1128\/CMR.10.1.35","article-title":"Yersinia pestis \u2013 etiological agent of plague","volume":"10","author":"Perry","year":"1997","journal-title":"Clin Microbiol Rev"},{"key":"R25","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1128\/IAI.73.3.1532-1542.2005","article-title":"Antibody against V-antigen prevents Yop-dependent growth of Yersinia pestis","volume":"73","author":"Philipovskiy","year":"2005","journal-title":"Infect Immun"},{"key":"R26","doi-asserted-by":"crossref","first-page":"3571","DOI":"10.1128\/IAI.01644-06","article-title":"Evaluation of the role of LcrV-Toll-like receptor 2-mediated immunomodulation in the virulence of Yersinia pestis","volume":"75","author":"Pouliot","year":"2007","journal-title":"Infect Immun"},{"key":"R27","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1146\/annurev.biochem.71.110601.135414","article-title":"Lipopolysaccharide endotoxins","volume":"71","author":"Raetz","year":"2002","journal-title":"Annu Rev Biochem"},{"key":"R28","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1111\/j.1365-2958.2004.04059.x","article-title":"Variation in lipid A structure in the pathogenic yersiniae","volume":"52","author":"Rebeil","year":"2004","journal-title":"Mol Microbiol"},{"key":"R29","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1038\/ni1528","article-title":"Pathogen subversion of cell-intrinsic innate immunity","volume":"8","author":"Roy","year":"2007","journal-title":"Nat Immunol"},{"key":"R30","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.1016\/0264-410X(95)00090-N","article-title":"A comparison of plague vaccine USP and EV76 vaccine induced protection against Yersinia pestis in a murine model","volume":"13","author":"Russell","year":"1995","journal-title":"Vaccine"},{"key":"R31","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1189\/jlb.0804442","article-title":"Structural organization of the neutrophil NADPH oxidase: phosphorylation and translocation during priming and activation","volume":"78","author":"Sheppard","year":"2005","journal-title":"J Leukoc Biol"},{"key":"R32","doi-asserted-by":"crossref","first-page":"2700","DOI":"10.1111\/j.1462-5822.2007.00990.x","article-title":"YopJ targets TRAF proteins to inhibit TLR-mediated NF- \u03baB, MAPK, and IRF3 signal transduction","volume":"9","author":"Sweet","year":"2007","journal-title":"Cell Microbiol"},{"key":"R33","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1146\/annurev.micro.59.030804.121320","article-title":"Yersinia outer proteins: role in modulation of host cell signaling responses and pathogenesis","volume":"59","author":"Viboud","year":"2005","journal-title":"Annu Rev Microbiol"},{"key":"R34","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1046\/j.1365-2958.2003.03350.x","article-title":"Proinflammatory signaling stimulated by the type III translocation factor YopB is counteracted by multiple effectors in epithelial cells infected with Yersinia pseudotuberculosis","volume":"47","author":"Viboud","year":"2003","journal-title":"Mol Microbiol"},{"key":"R35","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1016\/S0264-410X(00)00159-6","article-title":"A single dose sub-unit vaccine protects against pneumonic plague","volume":"19","author":"Williamson","year":"2000","journal-title":"Vaccine"},{"key":"R36","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1016\/j.vaccine.2006.09.052","article-title":"Kinetics of the immune response to the (F1+V) vaccine in models of bubonic and pneumonic plague","volume":"25","author":"Williamson","year":"2007","journal-title":"Vaccine"}],"container-title":["Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/micro\/10.1099\/mic.0.2008\/017566-0?crawler=true","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,1,24]],"date-time":"2020-01-24T15:13:56Z","timestamp":1579878836000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/micro\/10.1099\/mic.0.2008\/017566-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,7,1]]},"references-count":36,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2008,7,1]]}},"URL":"https:\/\/doi.org\/10.1099\/mic.0.2008\/017566-0","relation":{},"ISSN":["1350-0872","1465-2080"],"issn-type":[{"value":"1350-0872","type":"print"},{"value":"1465-2080","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,7,1]]}}}