{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,8]],"date-time":"2024-05-08T18:36:44Z","timestamp":1715193404880},"reference-count":42,"publisher":"Microbiology Society","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,9,1]]},"DOI":"10.1099\/vir.0.000193","type":"journal-article","created":{"date-parts":[[2015,5,22]],"date-time":"2015-05-22T02:45:35Z","timestamp":1432262735000},"page":"2522-2530","source":"Crossref","is-referenced-by-count":5,"title":["H5N1 influenza A virus with K193E and G225E double mutations in haemagglutinin is attenuated and immunogenic in mice"],"prefix":"10.1099","volume":"96","author":[{"given":"Peng-Fei","family":"Han","sequence":"first","affiliation":[{"name":"Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sen","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yin-Hui","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu-Chang","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao-Ping","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao-Yan","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shun-Ya","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qing-Yu","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheng-Feng","family":"Qin","sequence":"additional","affiliation":[{"name":"Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tao","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"345","reference":[{"key":"vir000193-Chen1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2012.01.090"},{"key":"vir000193-Conenello1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.0030141"},{"key":"vir000193-Contreras-Moreira1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/18.8.1141"},{"key":"vir000193-Dinh1","doi-asserted-by":"publisher","DOI":"10.2149\/tmh.2010-21"},{"key":"vir000193-Ekiert1","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1126\/science.1171491","article-title":"Antibody recognition of a highly conserved influenza virus epitope","volume":"1857","author":"Ekiert","year":"2009","journal-title":"Science"},{"key":"vir000193-Gambaryan1","doi-asserted-by":"publisher","DOI":"10.1006\/viro.1997.8572"},{"key":"vir000193-Garten1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1176225"},{"key":"vir000193-Gulati1","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2005.05.009"},{"key":"vir000193-Heneberg1","first-page":"624","article-title":"[Epidemiological review of pandemic Asiatic influenza in 1957]","volume":"16","author":"Heneberg","year":"1959","journal-title":"Vojnosanit Pregl"},{"key":"vir000193-Herfst1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1213362"},{"key":"vir000193-Hoffmann1","doi-asserted-by":"publisher","DOI":"10.1007\/s007050170002"},{"key":"vir000193-Hu1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2014.11.007"},{"key":"vir000193-Imai1","doi-asserted-by":"publisher","DOI":"10.1016\/j.coviro.2012.03.003"},{"key":"vir000193-Kiso1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)16934-1"},{"key":"vir000193-Koel1","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1126\/science.1244730","article-title":"Substitutions near the receptor binding site determine major antigenic change during influenza virus evolution","volume":"342","author":"Koel","year":"2013","journal-title":"Science"},{"key":"vir000193-Leroux-Roels1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61297-5"},{"key":"vir000193-Li1","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.030718-0"},{"key":"vir000193-Maines1","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2011.02.015"},{"key":"vir000193-Matrosovich1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.74.18.8502-8512.2000"},{"key":"vir000193-Mayrhofer1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02081-08"},{"key":"vir000193-Muench1","first-page":"493","article-title":"A simple method of estimating fifty per cent endpoints","volume":"27","author":"Muench","year":"1938","journal-title":"Am J Hyg"},{"key":"vir000193-Murakami1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00970-08"},{"key":"vir000193-Nobusawa1","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(91)90588-3"},{"key":"vir000193-Pappas1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0011158"},{"key":"vir000193-Prabakaran1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02175-09"},{"key":"vir000193-Rogers1","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(83)90150-2"},{"key":"vir000193-Russell1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1222526"},{"key":"vir000193-Shi1","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro3362"},{"key":"vir000193-Steel1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01920-08"},{"key":"vir000193-Stevens1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1124513"},{"key":"vir000193-Suguitan1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.0030360"},{"key":"vir000193-Taubenberger1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1209.05-0979"},{"key":"vir000193-Tharakaraman1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2013.05.035"},{"key":"vir000193-Tran-ToSu1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-14-S16-S7"},{"key":"vir000193-Wang1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00221-10"},{"key":"vir000193-Watanabe1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01899-07"},{"key":"vir000193-Watanabe12","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1002068"},{"key":"vir000193-WHO1","year":"2015"},{"key":"vir000193-Xu1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.06322-11"},{"key":"vir000193-Zhang1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00545-13"},{"key":"vir000193-Zheng1","doi-asserted-by":"publisher","DOI":"10.1258\/ebm.2010.010071"},{"key":"vir000193-Zhou1","doi-asserted-by":"publisher","DOI":"10.4149\/av_2011_03_195"}],"container-title":["Journal of General Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/jgv\/10.1099\/vir.0.000193?crawler=true","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,2,27]],"date-time":"2020-02-27T16:13:54Z","timestamp":1582820034000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/jgv\/10.1099\/vir.0.000193"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9,1]]},"references-count":42,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2015,9,1]]}},"URL":"https:\/\/doi.org\/10.1099\/vir.0.000193","relation":{},"ISSN":["0022-1317","1465-2099"],"issn-type":[{"value":"0022-1317","type":"print"},{"value":"1465-2099","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,9,1]]}}}