{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T21:07:16Z","timestamp":1791407236545,"version":"4.3.3"},"reference-count":57,"publisher":"Microbiology Society","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009,2,1]]},"abstract":"<jats:p>The henipaviruses, Nipah virus (NiV) and Hendra virus (HeV), are highly pathogenic zoonotic paramyxoviruses. Like many other paramyxoviruses, henipaviruses employ a process of co-transcriptional mRNA editing during transcription of the phosphoprotein (P) gene to generate additional mRNAs encoding the V and W proteins. The C protein is translated from the P mRNA, but in an alternate reading frame. Sequence analysis of multiple, cloned mRNAs showed that the mRNA editing frequencies of the P genes of the henipaviruses are higher than those reported for other paramyxoviruses. Antisera to synthetic peptides from the P, V, W and C proteins of NiV were generated to study their expression in infected cells. All proteins were detected in both infected cells and purified virions. In infected cells, the W protein was detected in the nucleus while P, V and C were found in the cytoplasm.<\/jats:p>","DOI":"10.1099\/vir.0.007294-0","type":"journal-article","created":{"date-parts":[[2009,1,13]],"date-time":"2009-01-13T00:38:33Z","timestamp":1231807113000},"page":"398-404","source":"Crossref","is-referenced-by-count":86,"title":["Determination of the henipavirus phosphoprotein gene mRNA editing frequencies and detection of the C, V and W proteins of Nipah virus in virus-infected cells"],"prefix":"10.1099","volume":"90","author":[{"given":"Michael K.","family":"Lo","sequence":"first","affiliation":[{"name":"The Research Institute at Nationwide Children's Hospital, Center for Vaccines and Immunity, 700 Children's Drive, Columbus, OH 43205, USA"},{"name":"The Ohio State University, College of Medicine, Department of Pediatrics, Columbus, OH 43205, USA"},{"name":"Emory University School of Medicine, Department of Microbiology and Immunology, 1510 Clifton Road, Atlanta, GA 30322, USA"},{"name":"Measles, Mumps, Rubella and Herpesviruses Laboratory Branch, 1600 Clifton Road, MS-C-22, Atlanta, GA 30333, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian H.","family":"Harcourt","sequence":"additional","affiliation":[{"name":"Measles, Mumps, Rubella and Herpesviruses Laboratory Branch, 1600 Clifton Road, MS-C-22, Atlanta, GA 30333, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce A.","family":"Mungall","sequence":"additional","affiliation":[{"name":"Commonwealth Scientific Industrial Research Organization, Australian Animal Health Laboratory, 5 Portarlington Road, East Geelong, Victoria, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azaibi","family":"Tamin","sequence":"additional","affiliation":[{"name":"Measles, Mumps, Rubella and Herpesviruses Laboratory Branch, 1600 Clifton Road, MS-C-22, Atlanta, GA 30333, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark E.","family":"Peeples","sequence":"additional","affiliation":[{"name":"The Ohio State University, College of Medicine, Department of Pediatrics, Columbus, OH 43205, USA"},{"name":"The Research Institute at Nationwide Children's Hospital, Center for Vaccines and Immunity, 700 Children's Drive, Columbus, OH 43205, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William J.","family":"Bellini","sequence":"additional","affiliation":[{"name":"Measles, Mumps, Rubella and Herpesviruses Laboratory Branch, 1600 Clifton Road, MS-C-22, Atlanta, GA 30333, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul A.","family":"Rota","sequence":"additional","affiliation":[{"name":"Measles, Mumps, Rubella and Herpesviruses Laboratory Branch, 1600 Clifton Road, MS-C-22, Atlanta, GA 30333, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"345","reference":[{"key":"R1","first-page":"301","article-title":"Risk factors for Nipah virus transmission, Port Dickson, Negeri Sembilan, Malaysia: results from a hospital-based case-control study","volume":"31","author":"Amal","year":"2000","journal-title":"Southeast Asian J Trop Med Public Health"},{"key":"R2","article-title":"Drug for bat virus combat. 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