{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T16:05:58Z","timestamp":1761581158907},"reference-count":32,"publisher":"Microbiology Society","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,4,1]]},"abstract":"<jats:p>Orthoreoviruses have been associated with a variety of diseases in domesticated poultry and wild-living birds. In 2002, a reovirus strain named Tv\u00e4rminne avian virus (TVAV), was identified in Finland in a crow showing neurological disorders. The objective of this study was the molecular characterization of this novel reovirus strain. Genome sequencing was performed by combining semiconductor sequencing and traditional capillary sequencing. Sequence and phylogenetic analyses showed that TVAV shares low nucleotide sequence identity with other reoviruses (range for each gene, 31\u201372\u200a%) including strains belonging to the species <jats:italic>Avian orthoreovirus<\/jats:italic>. The most closely related reovirus strain was an isolate identified in Steller sea lion. Our data indicate that TVAV is a divergent reovirus of avian origin that may be the first representative of a distinct virus species within the genus <jats:italic>Orthoreovirus<\/jats:italic>.<\/jats:p>","DOI":"10.1099\/vir.0.060699-0","type":"journal-article","created":{"date-parts":[[2014,1,14]],"date-time":"2014-01-14T04:54:08Z","timestamp":1389675248000},"page":"898-904","source":"Crossref","is-referenced-by-count":19,"title":["Complete genome analysis identifies Tv\u00e4rminne avian virus as a candidate new species within the genus Orthoreovirus"],"prefix":"10.1099","volume":"95","author":[{"given":"Eszter","family":"Dand\u00e1r","sequence":"first","affiliation":[{"name":"Institute for Veterinary Medical Research, Centre for Agricultural Research, Hungarian Academy of Sciences, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eili","family":"Huhtamo","sequence":"additional","affiliation":[{"name":"Department of Virology, Haartman Institute, Faculty of Medicine, University of Helsinki, Helsinki, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Szilvia L.","family":"Farkas","sequence":"additional","affiliation":[{"name":"Institute for Veterinary Medical Research, Centre for Agricultural Research, Hungarian Academy of Sciences, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mikl\u00f3s","family":"Oldal","sequence":"additional","affiliation":[{"name":"J\u00e1nos Szent\u00e1gothai Research Center, University of P\u00e9cs, P\u00e9cs, Hungary"},{"name":"Institute of Biology, Faculty of Sciences, University of P\u00e9cs, P\u00e9cs, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ferenc","family":"Jakab","sequence":"additional","affiliation":[{"name":"J\u00e1nos Szent\u00e1gothai Research Center, University of P\u00e9cs, P\u00e9cs, Hungary"},{"name":"Institute of Biology, Faculty of Sciences, University of P\u00e9cs, P\u00e9cs, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olli","family":"Vapalahti","sequence":"additional","affiliation":[{"name":"Department of Virology and Immunology, HUSLAB, Hospital District of Helsinki and Uusimaa, Helsinki, Finland"},{"name":"Department of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland"},{"name":"Department of Virology, Haartman Institute, Faculty of Medicine, University of Helsinki, Helsinki, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kriszti\u00e1n","family":"B\u00e1nyai","sequence":"additional","affiliation":[{"name":"Institute for Veterinary Medical Research, Centre for Agricultural Research, Hungarian Academy of Sciences, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"345","reference":[{"key":"r1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkq291"},{"key":"r2","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/S0022-2836(05)80360-2","article-title":"Basic local alignment search tool","volume":"215","author":"Altschul","year":"1990","journal-title":"J Mol Biol"},{"key":"r3","first-page":"541","article-title":"Family Reoviridae","volume-title":"Virus Taxonomy: Classification and Nomenclature of Viruses. 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