{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T06:46:42Z","timestamp":1791269202928,"version":"4.1.0"},"reference-count":50,"publisher":"Microbiology Society","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2003,1,1]]},"DOI":"10.1099\/vir.0.18606-0","type":"journal-article","created":{"date-parts":[[2003,2,6]],"date-time":"2003-02-06T22:11:18Z","timestamp":1044569478000},"page":"17-28","source":"Crossref","is-referenced-by-count":350,"title":["The human cytomegalovirus genome revisited: comparison with the chimpanzee cytomegalovirus genome\n               FN1"],"prefix":"10.1099","volume":"84","author":[{"given":"Andrew J.","family":"Davison","sequence":"first","affiliation":[{"name":"MRC Virology Unit, Institute of Virology, Church Street, Glasgow G11 5JR, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aidan","family":"Dolan","sequence":"additional","affiliation":[{"name":"MRC Virology Unit, Institute of Virology, Church Street, Glasgow G11 5JR, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parvis","family":"Akter","sequence":"additional","affiliation":[{"name":"MRC Virology Unit, Institute of Virology, Church Street, Glasgow G11 5JR, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clare","family":"Addison","sequence":"additional","affiliation":[{"name":"MRC Virology Unit, Institute of Virology, Church Street, Glasgow G11 5JR, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derrick J.","family":"Dargan","sequence":"additional","affiliation":[{"name":"MRC Virology Unit, Institute of Virology, Church Street, Glasgow G11 5JR, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald J.","family":"Alcendor","sequence":"additional","affiliation":[{"name":"Molecular Virology Laboratories, Oncology Center, Johns Hopkins School of Medicine, Baltimore, MD 21231, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duncan J.","family":"McGeoch","sequence":"additional","affiliation":[{"name":"MRC Virology Unit, Institute of Virology, Church Street, Glasgow G11 5JR, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary S.","family":"Hayward","sequence":"additional","affiliation":[{"name":"Molecular Virology Laboratories, Oncology Center, Johns Hopkins School of Medicine, Baltimore, MD 21231, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"345","reference":[{"key":"R1","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1099\/0022-1317-83-6-1315","article-title":"The products of human cytomegalovirus genes UL23, UL24, UL43 and US22 are tegument components","volume":"83","author":"Adair","year":"2002","journal-title":"J Gen Virol"},{"key":"R2","doi-asserted-by":"crossref","first-page":"4854","DOI":"10.1128\/JVI.75.10.4854-4870.2001","article-title":"Analysis and characterization of the complete genome of tupaia (tree shrew) herpesvirus","volume":"75","author":"Bahr","year":"2001","journal-title":"J Virol"},{"key":"R3","doi-asserted-by":"crossref","first-page":"6097","DOI":"10.1128\/JVI.70.9.6097-6105.1996","article-title":"Proteins associated with purified human cytomegalovirus particles","volume":"70","author":"Baldick","year":"1996","journal-title":"J Virol"},{"key":"R4","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1038\/331269a0","article-title":"Human cytomegalovirus encodes a glycoprotein homologous to MHC class I antigens","volume":"331","author":"Beck","year":"1988","journal-title":"Nature"},{"key":"R5","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1128\/JVI.70.1.78-83.1996","article-title":"Human cytomegalovirus clinical isolates carry at least 19 genes not found in laboratory strains","volume":"70","author":"Cha","year":"1996","journal-title":"J Virol"},{"key":"R6","doi-asserted-by":"crossref","first-page":"5757","DOI":"10.1128\/JVI.73.7.5757-5766.1999","article-title":"DNA microarrays of the complex human cytomegalovirus genome: profiling kinetic class with drug sensitivity of viral gene expression","volume":"73","author":"Chambers","year":"1999","journal-title":"J Virol"},{"key":"R7","doi-asserted-by":"crossref","first-page":"8590","DOI":"10.1128\/JVI.70.12.8590-8605.1996","article-title":"Synergistic interactions between overlapping binding sites for the serum response factor and ELK-1 proteins mediate both basal enhancement and phorbol ester responsiveness of primate cytomegalovirus major immediate-early promoters in monocyte and T-lymphocyte cell types","volume":"70","author":"Chan","year":"1996","journal-title":"J Virol"},{"key":"R8","first-page":"105","article-title":"Structural organization of the spliced immediate-early gene complex that encodes the major acidic nuclear (ie1) and transactivator (ie2) proteins of African green monkey cytomegalovirus","volume":"2","author":"Chang","year":"1995","journal-title":"J Biomed Sci"},{"key":"R9","first-page":"125","article-title":"Analysis of the protein coding content of the sequence of human cytomegalovirus strain AD169","volume":"154","author":"Chee","year":"1990","journal-title":"Curr Top Microbiol Immunol"},{"key":"R10","doi-asserted-by":"crossref","first-page":"9833","DOI":"10.1128\/JVI.71.12.9833-9836.1997","article-title":"The published DNA sequence of the human cytomegalovirus strain AD169 lacks 929 base pairs affecting genes UL42 and UL43","volume":"71","author":"Dargan","year":"1997","journal-title":"J Virol"},{"key":"R11","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.1128\/JVI.71.2.1521-1529.1997","article-title":"Identification and characterization of a G protein-coupled receptor homolog encoded by murine cytomegalovirus","volume":"71","author":"Davis-Poynter","year":"1997","journal-title":"J Virol"},{"key":"R12","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S1873-9768(06)80034-4","article-title":"Large scale DNA sequencing by manual methods","volume-title":"In Methods Gene Technology","volume":"vol. 2","author":"Davison","year":"1994"},{"key":"R13","doi-asserted-by":"crossref","first-page":"2010","DOI":"10.1128\/JVI.72.3.2010-2021.1998","article-title":"The genome sequence of herpes simplex virus type 2","volume":"72","author":"Dolan","year":"1998","journal-title":"J Virol"},{"key":"R14","doi-asserted-by":"crossref","first-page":"8040","DOI":"10.1128\/JVI.73.10.8040-8052.1999","article-title":"Human herpesvirus 6B genome sequence: coding content and comparison with human herpesvirus 6A","volume":"73","author":"Dominguez","year":"1999","journal-title":"J Virol"},{"key":"R15","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1101\/gr.8.3.186","article-title":"Base-calling of automated sequencer traces using phred. II. Error probabilities","volume":"8","author":"Ewing","year":"1998","journal-title":"Genome Res"},{"key":"R16","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1101\/gr.8.3.175","article-title":"Base-calling of automated sequencer traces using phred. I. Accuracy assessment","volume":"8","author":"Ewing","year":"1998","journal-title":"Genome Res"},{"key":"R17","doi-asserted-by":"crossref","first-page":"12536","DOI":"10.1073\/pnas.96.22.12536","article-title":"A cytomegalovirus-encoded mitochondria-localized inhibitor of apoptosis structurally unrelated to Bcl-2","volume":"96","author":"Goldmacher","year":"1999","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R18","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1006\/viro.1995.1228","article-title":"The DNA sequence of human herpesvirus-6: structure, coding content, and genome evolution","volume":"209","author":"Gompels","year":"1995","journal-title":"Virology"},{"key":"R19","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/0168-1702(87)90055-4","article-title":"Nucleotide sequence of the most abundantly transcribed early gene of human cytomegalovirus strain AD169","volume":"7","author":"Greenaway","year":"1987","journal-title":"Virus Res"},{"key":"R20","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1128\/JVI.26.3.718-723.1978","article-title":"Genetic analysis of a cytomegalovirus-like agent isolated from human brain","volume":"26","author":"Huang","year":"1978","journal-title":"J Virol"},{"key":"R21","doi-asserted-by":"crossref","first-page":"5272","DOI":"10.1128\/JVI.70.8.5272-5281.1996","article-title":"The variable 3\u2032 ends of a human cytomegalovirus oriLyt transcript (SRT) overlap an essential, conserved replicator element","volume":"70","author":"Huang","year":"1996","journal-title":"J Virol"},{"key":"R22","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/0042-6822(86)90176-5","article-title":"Organization and expression of the major genes from the long inverted repeat of the human cytomegalovirus genome","volume":"155","author":"Hutchinson","year":"1986","journal-title":"Virology"},{"key":"R23","doi-asserted-by":"crossref","first-page":"8053","DOI":"10.1128\/JVI.73.10.8053-8063.1999","article-title":"Comparison of the complete DNA sequences of human herpesvirus 6 variants A and B","volume":"73","author":"Isegawa","year":"1999","journal-title":"J Virol"},{"key":"R24","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1073\/pnas.97.4.1695","article-title":"Human cytomegalovirus harbors its own unique IL-10 homolog (cmvIL-10)","volume":"97","author":"Kotenko","year":"2000","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R25","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1006\/viro.2000.0195","article-title":"Primate cytomegaloviruses encode and express an IL-10-like protein","volume":"268","author":"Lockridge","year":"2000","journal-title":"Virology"},{"key":"R26","doi-asserted-by":"crossref","first-page":"10401","DOI":"10.1128\/JVI.74.22.10401-10406.2000","article-title":"Toward a comprehensive phylogeny for mammalian and avian herpesviruses","volume":"74","author":"McGeoch","year":"2000","journal-title":"J Virol"},{"key":"R27","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1006\/viro.1998.9105","article-title":"The DNA sequence of the RK strain of human herpesvirus 7","volume":"244","author":"Megaw","year":"1998","journal-title":"Virology"},{"issue":"2","key":"R28","first-page":"2629","article-title":"Cytomegaloviruses and their replication","volume-title":"In Fields Virology","volume":"vol","author":"Mocarski","year":"2001"},{"key":"R29","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1006\/viro.1997.8875","article-title":"Reassessing the organization of the UL42-UL43 region of the human cytomegalovirus strain AD169 genome","volume":"239","author":"Mocarski","year":"1997","journal-title":"Virology"},{"key":"R30","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/0092-8674(93)90118-A","article-title":"Molecular cloning, functional expression, and signaling characteristics of a C-C chemokine receptor","volume":"72","author":"Neote","year":"1993","journal-title":"Cell"},{"key":"R31","doi-asserted-by":"crossref","first-page":"5975","DOI":"10.1128\/JVI.70.9.5975-5989.1996","article-title":"Determination and analysis of the complete nucleotide sequence of human herpesvirus 7","volume":"70","author":"Nicholas","year":"1996","journal-title":"J Virol"},{"key":"R32","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1006\/jmbi.2001.4798","article-title":"In silico structural and functional analysis of the human cytomegalovirus (HHV5) genome","volume":"310","author":"Novotny","year":"2001","journal-title":"J Mol Biol"},{"issue":"2","key":"R33","first-page":"2675","article-title":"Cytomegalovirus. In Fields Virology","volume":"vol","author":"Pass","year":"2001"},{"key":"R34","doi-asserted-by":"crossref","first-page":"9839","DOI":"10.1073\/pnas.96.17.9839","article-title":"Cytomegalovirus encodes a potent \u03b1 chemokine","volume":"96","author":"Penfold","year":"1999","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R35","doi-asserted-by":"crossref","first-page":"2251","DOI":"10.1099\/0022-1317-69-9-2251","article-title":"Abundant 5\u2005kb RNA of human cytomegalovirus without a major translational reading frame","volume":"69","author":"Plachter","year":"1988","journal-title":"J Gen Virol"},{"key":"R36","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1002\/rmv.315","article-title":"A review of genetic differences between limited and extensively passaged human cytomegalovirus strains","volume":"11","author":"Prichard","year":"2001","journal-title":"Rev Med Virol"},{"key":"R37","doi-asserted-by":"crossref","first-page":"5502","DOI":"10.1128\/JVI.67.9.5502-5513.1993","article-title":"Spliced transcripts of human cytomegalovirus","volume":"67","author":"Rawlinson","year":"1993","journal-title":"J Virol"},{"key":"R38","doi-asserted-by":"crossref","first-page":"8833","DOI":"10.1128\/JVI.70.12.8833-8849.1996","article-title":"Analysis of the complete DNA sequence of murine cytomegalovirus","volume":"70","author":"Rawlinson","year":"1996","journal-title":"J Virol"},{"key":"R39","doi-asserted-by":"crossref","first-page":"1734","DOI":"10.1128\/JVI.69.3.1734-1740.1995","article-title":"Human cytomegalovirus UL102 gene","volume":"69","author":"Smith","year":"1995","journal-title":"J Virol"},{"key":"R40","first-page":"115","article-title":"The Staden package, 1998","volume":"132","author":"Staden","year":"2000","journal-title":"Methods Mol Biol"},{"key":"R41","doi-asserted-by":"crossref","first-page":"4836","DOI":"10.1128\/JVI.76.10.4836-4847.2002","article-title":"Open reading frame UL26 of human cytomegalovirus encodes a novel tegument protein that contains a strong transcriptional activation domain","volume":"76","author":"Stamminger","year":"2002","journal-title":"J Virol"},{"key":"R42","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1128\/JVI.49.1.190-199.1984","article-title":"Structural analysis of the major immediate early gene of human cytomegalovirus","volume":"49","author":"Stenberg","year":"1984","journal-title":"J Virol"},{"key":"R43","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1128\/JVI.56.3.665-675.1985","article-title":"Multiple spliced and unspliced transcripts from human cytomegalovirus immediate-early region 2 and evidence for a common initiation site within immediate-early region 1","volume":"56","author":"Stenberg","year":"1985","journal-title":"J Virol"},{"key":"R44","doi-asserted-by":"crossref","first-page":"2699","DOI":"10.1128\/JVI.63.6.2699-2708.1989","article-title":"Regulated expression of early and late RNAs and proteins from the human cytomegalovirus immediate-early gene region","volume":"63","author":"Stenberg","year":"1989","journal-title":"J Virol"},{"key":"R45","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1007\/BF01309376","article-title":"Initial characterization of four cytomegalovirus strains isolated from chimpanzees","volume":"82","author":"Swinkels","year":"1984","journal-title":"Arch Virol"},{"key":"R46","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1093\/nar\/14.1.437","article-title":"A computer program for translating DNA sequences into protein","volume":"14","author":"Taylor","year":"1986","journal-title":"Nucleic Acids Res"},{"key":"R47","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1099\/0022-1317-79-5-1197","article-title":"The DNA sequence of equine herpesvirus-4","volume":"79","author":"Telford","year":"1998","journal-title":"J Gen Virol"},{"key":"R48","doi-asserted-by":"crossref","first-page":"2931","DOI":"10.1093\/nar\/21.12.2931","article-title":"The human cytomegalovirus US3 immediate-early protein lacking the putative transmembrane domain regulates gene expression","volume":"21","author":"Tenney","year":"1993","journal-title":"Nucleic Acids Res"},{"key":"R49","doi-asserted-by":"crossref","first-page":"7656","DOI":"10.1128\/JVI.74.16.7656-7665.2000","article-title":"Complete DNA sequence of the rat cytomegalovirus genome","volume":"74","author":"Vink","year":"2000","journal-title":"J Virol"},{"key":"R50","doi-asserted-by":"crossref","first-page":"2316","DOI":"10.1128\/jvi.76.5.2316-2328.2002","article-title":"Construction of a self-excisable bacterial artificial chromosome containing the human cytomegalovirus genome and mutagenesis of the diploid TRL\/IRL13 gene","volume":"76","author":"Yu","year":"2002","journal-title":"J Virol"}],"container-title":["Journal of General Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/jgv\/10.1099\/vir.0.18606-0?crawler=true","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,2,20]],"date-time":"2020-02-20T07:13:53Z","timestamp":1582182833000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/jgv\/10.1099\/vir.0.18606-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,1,1]]},"references-count":50,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2003,1,1]]}},"URL":"https:\/\/doi.org\/10.1099\/vir.0.18606-0","relation":{},"ISSN":["0022-1317","1465-2099"],"issn-type":[{"value":"0022-1317","type":"print"},{"value":"1465-2099","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,1,1]]}}}