{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,6]],"date-time":"2024-08-06T01:42:46Z","timestamp":1722908566621},"reference-count":26,"publisher":"Microbiology Society","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2005,3,1]]},"abstract":"<jats:p>The Japanese Red Cross has been conducting a nucleic acid amplification test (NAT) screening for hepatitis B virus (HBV), hepatitis C virus and human immunodeficiency virus 1 among blood donors since July 1 1999. The first case of HBV genotype H was found and reported in Japan. Serological markers of HBV were not detected in this NAT-positive donation. It may be that the positive donation was in the serological window period at the early stage of infection. The complete genome of 3215\u2005nt was sequenced, and the sequence had 99\u00b73\u200a% homology with the strain from Los Angeles, USA (LSA2523). Here, a leucine zipper motif was found in the region of the HBV surface antigen conserved through genotypes A\u2013H.<\/jats:p>","DOI":"10.1099\/vir.0.80732-0","type":"journal-article","created":{"date-parts":[[2005,2,19]],"date-time":"2005-02-19T01:05:31Z","timestamp":1108775131000},"page":"595-599","source":"Crossref","is-referenced-by-count":19,"title":["Characterization of genotype H hepatitis B virus strain identified for the first time from a Japanese blood donor by nucleic acid amplification test"],"prefix":"10.1099","volume":"86","author":[{"given":"Hitoshi","family":"Ohnuma","sequence":"first","affiliation":[{"name":"Saitama Red Cross Blood Center, 1370-12, Takahagi, Hidaka, Saitama-ken 350-1213, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Yoshikawa","sequence":"additional","affiliation":[{"name":"Saitama Red Cross Blood Center, 1370-12, Takahagi, Hidaka, Saitama-ken 350-1213, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideaki","family":"Mizoguchi","sequence":"additional","affiliation":[{"name":"Saitama Red Cross Blood Center, 1370-12, Takahagi, Hidaka, Saitama-ken 350-1213, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroaki","family":"Okamoto","sequence":"additional","affiliation":[{"name":"Division of Virology, Department of Infection and Immunity, Jichi Medical School, Tochigi-ken 329-0498, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"the JRC NAT Screening Research Group","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"345","reference":[{"key":"R1","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1086\/516507","article-title":"Molecular epidemiology of hepatitis B virus in Central America reflected in the genetic variability of the small S gene","volume":"176","author":"Arauz-Ruiz","year":"1997","journal-title":"J Infect Dis"},{"key":"R2","doi-asserted-by":"crossref","first-page":"2059","DOI":"10.1099\/0022-1317-83-8-2059","article-title":"Genotype H: a new Amerindian genotype of hepatitis B virus revealed in Central America","volume":"83","author":"Arauz-Ruiz","year":"2002","journal-title":"J Gen Virol"},{"key":"R3","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1038\/281646a0","article-title":"Nucleotide sequence of the hepatitis B virus genome (subtype ayw) cloned in E. coli","volume":"281","author":"Galibert","year":"1979","journal-title":"Nature"},{"key":"R4","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1002\/jmv.20120","article-title":"Eight genotypes (A-H) of hepatitis B virus infecting patients from San Francisco and their demographic, clinical, and virological characteristics","volume":"73","author":"Kato","year":"2004","journal-title":"J Med Virol"},{"key":"R5","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1007\/s535-002-8130-z","article-title":"Clinical characteristics of patients infected with hepatitis B virus genotypes A","volume":"37","author":"Kobayashi","year":"2002","journal-title":"B, and C. 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