{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T22:32:15Z","timestamp":1791325935213,"version":"4.3.1"},"reference-count":39,"publisher":"Microbiology Society","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2005,6,1]]},"abstract":"<jats:p>Simian adenovirus 1 (SAdV-1) is one of many adenovirus strains that were isolated from Old World monkey cells during poliomyelitis vaccine production several decades ago. Despite the availability of these viruses, knowledge of their genetic content and phylogeny is rudimentary. In the present study, the genome sequence of SAdV-1 (34\u200a450\u2005bp) was determined and analysed. In regions where genetic content varies between primate adenoviruses, SAdV-1 has a single virus-associated RNA gene, six genes in each of the E3 and E4 regions and two fiber genes. SAdV-1 clusters phylogenetically with HAdV-40, a member of human adenovirus species HAdV-F, which also has two fiber genes. However, based on phylogenetic distances and other taxonomic criteria, SAdV-1 is proposed to represent a novel adenovirus species.<\/jats:p>","DOI":"10.1099\/vir.0.80757-0","type":"journal-article","created":{"date-parts":[[2005,5,24]],"date-time":"2005-05-24T22:18:24Z","timestamp":1116973104000},"page":"1681-1686","source":"Crossref","is-referenced-by-count":28,"title":["Complete genome sequence of simian adenovirus 1: an Old World monkey adenovirus with two fiber genes"],"prefix":"10.1099","volume":"86","author":[{"given":"G\u00e1bor M.","family":"Kov\u00e1cs","sequence":"first","affiliation":[{"name":"Veterinary Medical Research Institute, Hungarian Academy of Sciences, PO Box 18, H-1581 Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bal\u00e1zs","family":"Harrach","sequence":"additional","affiliation":[{"name":"Veterinary Medical Research Institute, Hungarian Academy of Sciences, PO Box 18, H-1581 Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander N.","family":"Zakhartchouk","sequence":"additional","affiliation":[{"name":"Vaccine and Infectious Disease Organization, University of Saskatchewan, Saskatoon, Saskatchewan, Canada S7N 5E3"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew J.","family":"Davison","sequence":"additional","affiliation":[{"name":"MRC Virology Unit, Institute of Virology, Church Street, Glasgow G11 5JR, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"345","reference":[{"key":"R1","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1126\/science.149.3685.754","article-title":"Adenovirus-associated defective virus particles","volume":"149","author":"Atchison","year":"1965","journal-title":"Science"},{"key":"R2","doi-asserted-by":"crossref","first-page":"6","DOI":"10.3181\/00379727-117-29482","article-title":"Neutralizing antibodies against simian viruses SV5 and SV20 in human sera","volume":"117","author":"Aulisio","year":"1964","journal-title":"Proc Soc Exp Biol Med"},{"key":"R3","doi-asserted-by":"crossref","first-page":"7968","DOI":"10.1128\/JVI.76.16.7968-7975.2002","article-title":"Comparative sequence analysis of the largest E1A proteins of human and simian adenoviruses","volume":"76","author":"Avvakumov","year":"2002","journal-title":"J Virol"},{"key":"R4","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/j.virol.2004.08.007","article-title":"Comprehensive sequence analysis of the E1A proteins of human and simian adenoviruses","volume":"329","author":"Avvakumov","year":"2004","journal-title":"Virology"},{"key":"R5","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1006\/viro.1994.1664","article-title":"Phylogenetic relationships among adenovirus serotypes","volume":"205","author":"Bailey","year":"1994","journal-title":"Virology"},{"key":"R6","first-page":"3","article-title":"Molecular evolution of adenoviruses","volume":"272","author":"Benk\u0151","year":"2003","journal-title":"Curr Top Microbiol Immunol"},{"key":"R7","first-page":"227","article-title":"Family Adenoviridae","volume-title":"In Virus Taxonomy: Seventh Report of the International Committee on Taxonomy of Viruses","author":"Benk\u0151","year":"2000"},{"key":"R8","doi-asserted-by":"crossref","first-page":"2507","DOI":"10.1099\/0022-1317-79-10-2507","article-title":"Sequence and transcriptional analysis of terminal regions of the fowl adenovirus type 8 genome","volume":"79","author":"Cao","year":"1998","journal-title":"J Gen Virol"},{"key":"R9","doi-asserted-by":"crossref","first-page":"2939","DOI":"10.1128\/JVI.70.5.2939-2949.1996","article-title":"The complete DNA sequence and genomic organization of the avian adenovirus CELO","volume":"70","author":"Chiocca","year":"1996","journal-title":"J Virol"},{"key":"R10","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.1006\/jmbi.1993.1687","article-title":"The DNA sequence of adenovirus type 40","volume":"234","author":"Davison","year":"1993","journal-title":"J Mol Biol"},{"key":"R11","doi-asserted-by":"crossref","first-page":"2895","DOI":"10.1099\/vir.0.19497-0","article-title":"Genetic content and evolution of adenoviruses","volume":"84","author":"Davison","year":"2003","journal-title":"J Gen Virol"},{"key":"R12","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1099\/0022-1317-44-1-69","article-title":"Physicochemical properties and restriction maps of simian adenovirus type 38 DNA","volume":"44","author":"Dimitrov","year":"1979","journal-title":"J Gen Virol"},{"key":"R13","doi-asserted-by":"crossref","first-page":"11603","DOI":"10.1128\/JVI.75.23.11603-11613.2001","article-title":"Replication-defective vector based on a chimpanzee adenovirus","volume":"75","author":"Farina","year":"2001","journal-title":"J Virol"},{"key":"R14","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1038\/sj.onc.1206151","article-title":"Selective PDZ protein-dependent stimulation of phosphatidylinositol 3-kinase by the adenovirus E4-ORF1 oncoprotein","volume":"22","author":"Frese","year":"2003","journal-title":"Oncogene"},{"key":"R15","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1007\/BF01315225","article-title":"The fibers of fowl adenoviruses","volume":"72","author":"Gelderblom","year":"1982","journal-title":"Arch Virol"},{"key":"R16","first-page":"15","article-title":"Study of enteric viruses of simian origin","volume":"68","author":"Hoffert","year":"1958","journal-title":"Am J Hyg"},{"key":"R17","first-page":"413","article-title":"New viral agents recovered from tissue cultures of monkey kidney cells","volume":"67","author":"Hull","year":"1957","journal-title":"II. Problems of isolation and identification. Ann N Y Acad Sci"},{"key":"R18","first-page":"204","article-title":"New viral agents recovered from tissue cultures of monkey kidney cells. I. Origin and properties of cytopathogenic agents S.V.1,S.V.2, S.V.4, S.V.5, S.V.6, S.V.11, S.V.12 andS.V.15","volume":"63","author":"Hull","year":"1956","journal-title":"Am J Hyg"},{"key":"R19","first-page":"31","article-title":"New viral agents recovered from tissue cultures of monkey kidney cells. III. Recovery of additional agents both from cultures of monkey tissues and directly from tissues and excreta","volume":"68","author":"Hull","year":"1958","journal-title":"Am J Hyg"},{"key":"R20","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1126\/science.150.3699.1044","article-title":"Oncogenicity of the simian adenoviruses","volume":"150","author":"Hull","year":"1965","journal-title":"Science"},{"key":"R21","doi-asserted-by":"crossref","first-page":"3361","DOI":"10.1099\/vir.0.80386-0","article-title":"Characterization and manipulation of the human adenovirus 4 genome","volume":"85","author":"Jacobs","year":"2004","journal-title":"J Gen Virol"},{"key":"R22","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1159\/000149142","article-title":"Simian virus nomenclature, 1980","volume":"13","author":"Kalter","year":"1980","journal-title":"Intervirology"},{"key":"R23","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1006\/viro.1993.1009","article-title":"Adenovirus type 40 virions contain two distinct fibers","volume":"192","author":"Kidd","year":"1993","journal-title":"Virology"},{"key":"R24","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1006\/viro.1995.1049","article-title":"Human and simian adenoviruses: phylogenetic inferences from analysis of VA RNA genes","volume":"207","author":"Kidd","year":"1995","journal-title":"Virology"},{"key":"R25","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.virusres.2003.08.010","article-title":"Phylogenetic analysis of the hexon and protease genes of a fish adenovirus isolated from white sturgeon ( Acipenser transmontanus ) supports the proposal for a new adenovirus genus","volume":"98","author":"Kov\u00e1cs","year":"2003","journal-title":"Virus Res"},{"key":"R26","doi-asserted-by":"crossref","first-page":"2799","DOI":"10.1099\/vir.0.80225-0","article-title":"Analysis of the first complete genome sequence of an Old World monkey adenovirus reveals a lineage distinct from the six human adenovirus species","volume":"85","author":"Kov\u00e1cs","year":"2004","journal-title":"J Gen Virol"},{"key":"R27","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1093\/bioinformatics\/17.12.1244","article-title":"mega2: molecular evolutionary genetic analysis software","volume":"17","author":"Kumar","year":"2001","journal-title":"Bioinformatics"},{"key":"R28","doi-asserted-by":"crossref","first-page":"2131","DOI":"10.1099\/0022-1317-78-9-2131","article-title":"E4 gene function in adenovirus, adenovirus vector and adeno-associated virus infections","volume":"78","author":"Leppard","year":"1997","journal-title":"J Gen Virol"},{"key":"R29","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1093\/nar\/5.3.999","article-title":"Analysis of the genome of type 7 simian adenovirus using restrictases","volume":"5","author":"Naroditsky","year":"1978","journal-title":"Nucleic Acids Res"},{"key":"R30","doi-asserted-by":"crossref","DOI":"10.1093\/nar\/18.7.1901","article-title":"Human enteric adenovirus type 41 (Tak) contains a second fiber protein gene","volume":"18","author":"Pieniazek","year":"1990","journal-title":"Nucleic Acids Res"},{"key":"R31","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1093\/oxfordjournals.aje.a120781","article-title":"A classification of simian adenoviruses based on hemagglutination","volume":"86","author":"Rapoza","year":"1967","journal-title":"Am J Epidemiol"},{"key":"R32","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1038\/2151186a0","article-title":"Association of AAV-1 with simian adenoviruses","volume":"215","author":"Rapoza","year":"1967","journal-title":"Nature"},{"key":"R33","first-page":"120","article-title":"A hemaglutination-inhibition technique for typing adenoviruses","volume":"71","author":"Rosen","year":"1960","journal-title":"Am J Hyg"},{"key":"R34","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.virol.2004.03.047","article-title":"Complete nucleotide sequences and genome organization of four chimpanzee adenoviruses","volume":"324","author":"Roy","year":"2004","journal-title":"Virology"},{"key":"R35","doi-asserted-by":"crossref","first-page":"2573","DOI":"10.1099\/0022-1317-81-11-2573","article-title":"Update on adenovirus and its vectors","volume":"81","author":"Russell","year":"2000","journal-title":"J Gen Virol"},{"key":"R36","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1128\/JVI.68.1.379-389.1994","article-title":"Nucleotide sequence of human adenovirus type 12 DNA: comparative functional analysis","volume":"68","author":"Sprengel","year":"1994","journal-title":"J Virol"},{"key":"R37","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1099\/0022-1317-76-3-481","article-title":"The subgroup F adenoviruses","volume":"76","author":"Tiemessen","year":"1995","journal-title":"J Gen Virol"},{"key":"R38","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1099\/vir.0.19697-0","article-title":"DNA sequencing and analysis of the right-hand part of the genome of the unique bovine adenovirus type 10","volume":"85","author":"Ursu","year":"2004","journal-title":"J Gen Virol"},{"key":"R39","first-page":"19","article-title":"Mastadenovirus . In The Springer Index of Viruses","author":"Wadell","year":"2002"}],"container-title":["Journal of General Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/jgv\/10.1099\/vir.0.80757-0?crawler=true","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,22]],"date-time":"2020-10-22T16:33:06Z","timestamp":1603384386000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/jgv\/10.1099\/vir.0.80757-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,6,1]]},"references-count":39,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2005,6,1]]}},"URL":"https:\/\/doi.org\/10.1099\/vir.0.80757-0","relation":{},"ISSN":["0022-1317","1465-2099"],"issn-type":[{"value":"0022-1317","type":"print"},{"value":"1465-2099","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,6,1]]}}}