{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T10:32:41Z","timestamp":1789295561540,"version":"build-2803163510"},"reference-count":45,"publisher":"Microbiology Society","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,4,1]]},"abstract":"<jats:p>To provide a better understanding of hantavirus epidemiology in China, Korean field mice (<jats:italic>Apodemus peninsulae<\/jats:italic>) and striped field mice (<jats:italic>Apodemus agrarius<\/jats:italic>) were captured in Jilin province, China, where haemorrhagic fever with renal syndrome (HFRS) is endemic. Hantavirus antigens were detected in eight of the 130 <jats:italic>A. peninsulae<\/jats:italic> individuals and in four of the 193 <jats:italic>A. agrarius<\/jats:italic> individuals by using an immunofluorescence assay. Partial S and M segments were amplified from all of the antigen-positive samples. Furthermore, two hantaviruses (CJAp89 and CJAp93) were isolated successfully in cell culture and the entire S and M segments were amplified from one of them (CJAp93). Phylogenetic analysis of these sequences (partial or complete) showed that hantaviruses carried by <jats:italic>A. peninsulae<\/jats:italic> and <jats:italic>A. agrarius<\/jats:italic> form two distinct lineages, although viruses carried by <jats:italic>A. peninsulae<\/jats:italic> are similar to those isolated previously from <jats:italic>A. agrarius<\/jats:italic> in China and from HFRS patients in Russia. However, the viruses detected in <jats:italic>A. peninsulae<\/jats:italic> in China are genetically different from those detected in <jats:italic>A. peninsulae<\/jats:italic> in other countries. These data suggest that <jats:italic>A. peninsulae<\/jats:italic> is also a natural host for HTNV in north-eastern China.<\/jats:p>","DOI":"10.1099\/vir.0.82534-0","type":"journal-article","created":{"date-parts":[[2007,3,20]],"date-time":"2007-03-20T19:23:13Z","timestamp":1174418593000},"page":"1295-1301","source":"Crossref","is-referenced-by-count":24,"title":["Isolation and characterization of hantavirus carried by Apodemus peninsulae in Jilin, China"],"prefix":"10.1099","volume":"88","author":[{"given":"Yong-Zhen","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Hemorrhagic Fever, Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping Liuzi 5, Beijing 102206, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Zou","sequence":"additional","affiliation":[{"name":"Department of Hemorrhagic Fever, Institute for Communicable Disease Control and Prevention, 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