{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T02:08:44Z","timestamp":1773281324748,"version":"3.50.1"},"reference-count":0,"publisher":"Microbiology Society","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2000,2,1]]},"abstract":"<jats:p>Summary: With a liquid membrane potassium-sensitive electrode it was shown that lethal concentrations of the polyene antibiotics amphotericin B, candicidin and nystatin caused leakage of 90% of non-bound potassium ions from <jats:italic>Candida albicans<\/jats:italic>. Accurate and rapid determinations of rates of potassium leakage were made directly in suspensions of Candida. Leakage patterns for the three polyenes were very similar, suggesting a common site of action. Differences were noted in the rates of potassium efflux with organisms from cultures of differing ages.<\/jats:p>","DOI":"10.1099\/00221287-81-2-325","type":"journal-article","created":{"date-parts":[[2009,6,8]],"date-time":"2009-06-08T23:47:47Z","timestamp":1244504867000},"page":"325-330","source":"Crossref","is-referenced-by-count":41,"title":["The Mode of Action of Polyene Antibiotics; Induced Potassium Leakage in Candida albicans"],"prefix":"10.1099","volume":"81","author":[{"given":"S. M.","family":"HAMMOND","sequence":"first","affiliation":[]},{"given":"P. A.","family":"LAMBERT","sequence":"additional","affiliation":[]},{"given":"B. N.","family":"KLIGER","sequence":"additional","affiliation":[]}],"member":"345","container-title":["Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/micro\/10.1099\/00221287-81-2-325?crawler=true","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,12,21]],"date-time":"2020-12-21T08:17:21Z","timestamp":1608538641000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.microbiologyresearch.org\/content\/journal\/micro\/10.1099\/00221287-81-2-325"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,2,1]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2000,2,1]]}},"URL":"https:\/\/doi.org\/10.1099\/00221287-81-2-325","relation":{},"ISSN":["1350-0872","1465-2080"],"issn-type":[{"value":"1350-0872","type":"print"},{"value":"1465-2080","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,2,1]]}}}