{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T06:11:16Z","timestamp":1790316676541,"version":"4.1.0"},"reference-count":21,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"name":"Hospal"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Scientific World Journal"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>Recent reports indicate the possible role of bladder CO<jats:sub>2<\/jats:sub>as a marker of low perfusion states. To test this hypothesis, shock was induced in six beagle dogs with 1\u2009mg\/kg of<jats:italic>E. coli<\/jats:italic>lipopolysaccharide, gastric CO<jats:sub>2<\/jats:sub>(CO<jats:sub>2<\/jats:sub>-G) was measured with a continuous monitor, and a pulmonary catheter was inserted in the bladder to measure CO<jats:sub>2<\/jats:sub>(CO<jats:sub>2<\/jats:sub>-B). Levels of CO<jats:sub>2<\/jats:sub>-B were found to be lower than those of CO<jats:sub>2<\/jats:sub>-G, with a mean difference of 36.8\u2009mmHg (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn fontstyle=\"italic\">0.001<\/mml:mn><\/mml:math>), and correlation between both measurements was poor (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:msup><mml:mrow><mml:mi>r<\/mml:mi><\/mml:mrow><mml:mrow><mml:mn>2<\/mml:mn><\/mml:mrow><\/mml:msup><mml:mo>=<\/mml:mo><mml:mn>0.16<\/mml:mn><\/mml:math>). Even when the correlation between CO<jats:sub>2<\/jats:sub>-G and<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mo>\u0394<\/mml:mo><\/mml:math>CO<jats:sub>2<\/jats:sub>-G was narrow (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:msup><mml:mrow><mml:mi>r<\/mml:mi><\/mml:mrow><mml:mrow><mml:mn>2<\/mml:mn><\/mml:mrow><\/mml:msup><mml:mo>=<\/mml:mo><mml:mn>0.86<\/mml:mn><\/mml:math>), this was not the case for the relationship between CO<jats:sub>2<\/jats:sub>-B and<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mo>\u0394<\/mml:mo><\/mml:math>CO<jats:sub>2<\/jats:sub>-B (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:msup><mml:mrow><mml:mi>r<\/mml:mi><\/mml:mrow><mml:mrow><mml:mn>2<\/mml:mn><\/mml:mrow><\/mml:msup><mml:mo>=<\/mml:mo><mml:mn>0.29<\/mml:mn><\/mml:math>). Finally, the correlation between CO<jats:sub>2<\/jats:sub>-G and base deficit was good (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:msup><mml:mrow><mml:mi>r<\/mml:mi><\/mml:mrow><mml:mrow><mml:mn>2<\/mml:mn><\/mml:mrow><\/mml:msup><mml:mo>=<\/mml:mo><mml:mn>0.45<\/mml:mn><\/mml:math>), which was not the case with the CO<jats:sub>2<\/jats:sub>-B correlation (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:msup><mml:mrow><mml:mi>r<\/mml:mi><\/mml:mrow><mml:mrow><mml:mn>2<\/mml:mn><\/mml:mrow><\/mml:msup><mml:mo>=<\/mml:mo><mml:mn>0.03<\/mml:mn><\/mml:math>). In our experience, bladder CO<jats:sub>2<\/jats:sub>does not correlate to hemodynamic parameters and does not substitute gastric CO<jats:sub>2<\/jats:sub>for detection of low perfusion states.<\/jats:p>","DOI":"10.1100\/2012\/360378","type":"journal-article","created":{"date-parts":[[2012,4,19]],"date-time":"2012-04-19T22:03:25Z","timestamp":1334873005000},"page":"1-5","source":"Crossref","is-referenced-by-count":4,"title":["Bladder Mucosal CO<sub>2<\/sub>Compared with Gastric Mucosal CO<sub>2<\/sub>as a Marker for Low Perfusion States in Septic Shock"],"prefix":"10.1100","volume":"2012","author":[{"given":"Gemma","family":"Seller-P\u00e9rez","sequence":"first","affiliation":[{"name":"Intensive Care Medicine, University Hospital Carlos Haya, 29010 M\u00e1laga, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel E.","family":"Herrera-Guti\u00e9rrez","sequence":"additional","affiliation":[{"name":"Intensive Care Medicine, University Hospital Carlos Haya, 29010 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