{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T13:57:23Z","timestamp":1773237443298,"version":"3.50.1"},"reference-count":13,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Scientific World Journal"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. To evaluate the effect of maternal smoking during pregnancy on levels of umbilical cord erythropoietin.<jats:italic>Methods<\/jats:italic>. Erythropoietin levels were measured in umbilical cord sera of 60 newborns who were delivered vaginally at term. There were 20 (33%) smoking and 40 (67%) nonsmoking mothers.<jats:italic>Results<\/jats:italic>. Mean cord serum erythropoietin levels were significantly lower in the nonsmokers (nonsmokers, 24 \u00b1 9\u2009IU\/L; smokers, 61 \u00b1 46\u2009IU\/L;<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>.001<\/mml:mn><\/mml:mrow><\/mml:math>). There was a significant positive correlation between the number of cigarettes smoked per day and cord serum erythropoietin levels (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mi>r<\/mml:mi><\/mml:math>, 0.58;<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mrow><mml:mi>P<\/mml:mi><mml:mo>\u2264<\/mml:mo><mml:mn>.05<\/mml:mn><\/mml:mrow><\/mml:math>).<jats:italic>Conclusions<\/jats:italic>. Smoking during pregnancy is associated with increased levels of umbilical cord erythropoietin at birth. This may indicate a risk of fetal hypoxia and growth restriction. Education and encouragement of cessation of smoking during pregnancy are important to avoid associated fetal and maternal morbidity and mortality.<\/jats:p>","DOI":"10.1100\/2012\/420763","type":"journal-article","created":{"date-parts":[[2012,5,1]],"date-time":"2012-05-01T22:01:14Z","timestamp":1335909674000},"page":"1-3","source":"Crossref","is-referenced-by-count":10,"title":["Umbilical Cord Serum Erythropoietin Levels and Maternal Smoking in Pregnancy"],"prefix":"10.1100","volume":"2012","author":[{"given":"Soner","family":"Sazak","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Vakif Gureba Teaching and Training Hospital, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sinan Mahir","family":"Kay\u0131ran","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, American Hospital, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yahya","family":"Paksoy","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Vakif Gureba Teaching and Training Hospital, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(99)00622-5"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(98)70415-6"},{"issue":"3","key":"3","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1590\/S1516-31802004000300004","volume":"122","year":"2004","journal-title":"Sao Paulo Medical Journal"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0412.2000.079004276.x"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1159\/000153094"},{"issue":"2","key":"8","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/0002-9378(89)90466-3","volume":"160","year":"1989","journal-title":"American Journal of Obstetrics and Gynecology"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(05)82459-X"},{"issue":"2","key":"10","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1172\/JCI113363","volume":"81","year":"1988","journal-title":"Journal of Clinical Investigation"},{"issue":"3","key":"11","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1177\/41.3.8429197","volume":"41","year":"1993","journal-title":"Journal of Histochemistry and Cytochemistry"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3016.2006.00707.x"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1007\/s004310051152"},{"issue":"2","key":"12","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1055\/s-2007-994298","volume":"13","year":"1996","journal-title":"American Journal of Perinatology"},{"issue":"3","key":"13","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/S0022-3476(94)70380-9","volume":"124","year":"1994","journal-title":"Journal of Pediatrics"}],"container-title":["The Scientific World Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/tswj\/2012\/420763.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/tswj\/2012\/420763.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/tswj\/2012\/420763.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,20]],"date-time":"2017-06-20T18:11:58Z","timestamp":1497982318000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/tswj\/2012\/420763\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":13,"alternative-id":["420763","420763"],"URL":"https:\/\/doi.org\/10.1100\/2012\/420763","relation":{},"ISSN":["1537-744X"],"issn-type":[{"value":"1537-744X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012]]}}}