{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,9]],"date-time":"2025-11-09T03:33:02Z","timestamp":1762659182134},"reference-count":32,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Scientific World Journal"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>The aim of this work was to determine the presence of galectin-10 in nasal lavage fluid (NLF) of patients with aspirin-sensitive respiratory disease (ASRD) before and after challenge with L-ASA (aspirin) by ELISA. Fifteen ASRD patients, ten aspirin-tolerant asthmatics (ATA), and fifteen healthy controls (HC) were studied. The baseline presence of Galectin-10 in PBMC was determined using real time PCR. Galectin-10 was evaluated in tissue of nasal polyps by western blot. Our results showed a lower expression in PBMC of ASRD patients than in ATA and healthy controls. However, a higher concentration of galectin-10 in NLF was found in ASRD patients before and after L-ASA challenge; western blot confirmed a high expression of galectin-10 in tissue from nasal polyps obtained from ASRD patients. Our results suggest a probable role of galectin-10 in the inflammatory response observed in ASRD patients; however, confirmatory studies are needed.<\/jats:p>","DOI":"10.1100\/2012\/474020","type":"journal-article","created":{"date-parts":[[2012,4,30]],"date-time":"2012-04-30T22:03:31Z","timestamp":1335823411000},"page":"1-6","source":"Crossref","is-referenced-by-count":11,"title":["Galectin-10 Is Released in the Nasal Lavage Fluid of Patients with Aspirin-Sensitive Respiratory Disease"],"prefix":"10.1100","volume":"2012","author":[{"given":"Ma. Cristina","family":"Negrete-Garcia","sequence":"first","affiliation":[{"name":"Department of Immunogenetics and Allergy, Instituto Nacional de Enfermedades Respiratorias, Calzada Tlalpan 4502, 14080 Mexico, DF, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carla Yoneli","family":"Jim\u00e9nez-Torres","sequence":"additional","affiliation":[{"name":"Department of Immunogenetics and Allergy, Instituto Nacional de Enfermedades Respiratorias, Calzada Tlalpan 4502, 14080 Mexico, DF, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noe","family":"Alvarado-V\u00e1squez","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Instituto Nacional de Enfermedades Respiratorias, Calzada Tlalpan 4502, 14080 Mexico, DF, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. Rosal\u00eda","family":"Montes-Vizuet","sequence":"additional","affiliation":[{"name":"Department of Immunogenetics and Allergy, Instituto Nacional de Enfermedades Respiratorias, Calzada Tlalpan 4502, 14080 Mexico, DF, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. R.","family":"Vel\u00e1zquez-Rodriguez","sequence":"additional","affiliation":[{"name":"Department of Immunogenetics and Allergy, Instituto Nacional de Enfermedades Respiratorias, Calzada Tlalpan 4502, 14080 Mexico, DF, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. Carmen","family":"Jimenez-Martinez","sequence":"additional","affiliation":[{"name":"Department of Immunology, Research Unit, Institute of Ophthalmology, Foundation Conde de Valenciana, 06800 Mexico, DF, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis Manuel","family":"Teran-Ju\u00e1rez","sequence":"additional","affiliation":[{"name":"Department of Immunogenetics and Allergy, Instituto Nacional de Enfermedades Respiratorias, Calzada Tlalpan 4502, 14080 Mexico, DF, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2006.07.024"},{"issue":"5","key":"2","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1016\/S1081-1206(10)62084-4","volume":"89","year":"2002","journal-title":"Annals of Allergy, Asthma and Immunology"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3003.2000.016003432.x"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1017\/S1462399408000719"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1093\/glycob\/9.10.979"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1023\/B:GLYC.0000014088.21242.e0"},{"issue":"6","key":"7","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1084\/jem.155.6.1597","volume":"155","year":"1982","journal-title":"Journal of Experimental Medicine"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-01-069229"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1006\/clim.2000.4912"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2007.01558.x"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1136\/thorax.55.11.921"},{"issue":"5","key":"12","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/S0091-6749(98)70163-0","volume":"101","year":"1998","journal-title":"Journal of Allergy and Clinical Immunology"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2007.01409.x"},{"issue":"6","key":"14","first-page":"190","volume":"47","year":"2000","journal-title":"Revista Alergia Mexico"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2008.73"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1038\/227680a0"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3083.2007.01986.x"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2009.05131.x"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellimm.2011.06.003"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-4165(02)00314-8"},{"key":"21"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1021\/pr050341h"},{"issue":"11","key":"23","doi-asserted-by":"crossref","first-page":"1883","DOI":"10.1093\/clinchem\/48.11.1883","volume":"48","year":"2002","journal-title":"Clinical Chemistry"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1093\/glycob\/cwp203"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.4168\/aair.2011.3.1.3"},{"key":"26","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1053\/rmed.2000.0911","volume":"94","year":"2000","journal-title":"Respiratory Medicine"},{"issue":"3","key":"27","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S1081-1206(10)62815-3","volume":"81","year":"1998","journal-title":"Annals of Allergy, Asthma and Immunology"},{"issue":"7","key":"28","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1177\/014556130408300717","volume":"83","year":"2004","journal-title":"Ear, Nose and Throat Journal"},{"issue":"5 i","key":"29","first-page":"867","volume":"81","year":"1988","journal-title":"Journal of Allergy and Clinical Immunology"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00003.2005"},{"issue":"4","key":"31","first-page":"395","volume":"49","year":"2010","journal-title":"Acta clinica Croatica"},{"key":"32","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.2008.03190.x"}],"container-title":["The Scientific World Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/tswj\/2012\/474020.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/tswj\/2012\/474020.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/tswj\/2012\/474020.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,6]],"date-time":"2020-07-06T23:15:58Z","timestamp":1594077358000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/tswj\/2012\/474020\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":32,"alternative-id":["474020","474020"],"URL":"https:\/\/doi.org\/10.1100\/2012\/474020","relation":{},"ISSN":["1537-744X"],"issn-type":[{"value":"1537-744X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012]]}}}