{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T13:18:16Z","timestamp":1762521496369},"reference-count":11,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Scientific World Journal"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>The efficacy of toltrazuril treatment was assessed in two experiments in Polish swine herds. Experiment 1 included a toltrazuril treatment group, Group A (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">410<\/mml:mn><\/mml:math>), and untreated control, Group B (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">386<\/mml:mn><\/mml:math>). Time to sale in Group A was 108 days versus 120 days for Group B, with average body weights at sale of 114.2\u2009kg and 108.8\u2009kg, respectively (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn fontstyle=\"italic\">0.05<\/mml:mn><\/mml:math>). In experiment 2, the health status and body weight gain of 238 piglets treated with toltrazuril (Group D) were compared to 235 untreated piglets (Group K). A similar difference was observed in average body weights of slaughtered animals, being on average 104\u2009kg in Group D and 101\u2009kg in Group K (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn fontstyle=\"italic\">0.01<\/mml:mn><\/mml:math>). Animals from Group D were slaughtered 5 days earlier than animals from Group K (day 166 versus day 171). Data from clinical trials suggest treatment of coccidiosis with toltrazuril offering potential for improved animal welfare and yields, however this has remained unproven in field conditions in large swine production facilities. The present study confirms the efficacy of toltrazuril treatment when used in the field and the subsequent positive impact on time to weaning, time to market, and on weight gain at all time points.<\/jats:p>","DOI":"10.1100\/2012\/486324","type":"journal-article","created":{"date-parts":[[2012,4,1]],"date-time":"2012-04-01T18:02:29Z","timestamp":1333303349000},"page":"1-4","source":"Crossref","is-referenced-by-count":11,"title":["Effect of Isosporiasis Prevention with Toltrazuril on Long-Term Pig Performance"],"prefix":"10.1100","volume":"2012","author":[{"given":"K.","family":"Rypula","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases and Veterinary Administration, Department of Epizootiology with Clinic of Birds and Exotic Animals, Faculty of Veterinary Medicine, Wroc\u0142aw University of Environmental and Life Sciences, Grunwaldzki Square 45, 50-366 Wroc\u0142aw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Porowski","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases and Veterinary Administration, Department of Epizootiology with Clinic of Birds and Exotic Animals, Faculty of Veterinary Medicine, Wroc\u0142aw University of Environmental and Life Sciences, Grunwaldzki Square 45, 50-366 Wroc\u0142aw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Kaba","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases and Epidemiology, Department of Large Animal Diseases, Faculty of Veterinary Medicine, Warsaw University of Life Sciences\u2014SGGW, Nowoursynowska 159c, 02-776 Warsaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Gorczykowski","sequence":"additional","affiliation":[{"name":"Divison of Parasitology, Department of Internal Diseases with Clinic of Horses, Dogs and Cats, Faculty of Veterinary Medicine, Agricultural University of Wroc\u0142aw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Deniz","sequence":"additional","affiliation":[{"name":"Bayer HealthCare Animal Health, Leverkusen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"issue":"1","key":"11","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1177\/030098588001700109","volume":"17","year":"1980","journal-title":"Veterinary Pathology"},{"issue":"4","key":"8","first-page":"401","volume":"47","year":"1983","journal-title":"Canadian Journal of Comparative Medicine"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-005-0030-x"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0450.2005.00824.x"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2009.04.028"},{"issue":"15","key":"1","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1136\/vr.143.15.417","volume":"143","year":"1998","journal-title":"Veterinary Record"},{"issue":"12","key":"13","first-page":"682","volume":"62","year":"2007","journal-title":"Tierarztliche Umschau"},{"key":"4","first-page":"73","volume":"63","year":"2010","journal-title":"The Pig Journal"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2005.07.002"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-007-0521-z"},{"issue":"4","key":"2","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1111\/j.1751-0813.1995.tb15034.x","volume":"72","year":"1995","journal-title":"Australian Veterinary Journal"}],"container-title":["The Scientific World Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/tswj\/2012\/486324.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/tswj\/2012\/486324.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/tswj\/2012\/486324.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,20]],"date-time":"2017-06-20T12:26:07Z","timestamp":1497961567000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/tswj\/2012\/486324\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":11,"alternative-id":["486324","486324"],"URL":"https:\/\/doi.org\/10.1100\/2012\/486324","relation":{},"ISSN":["1537-744X"],"issn-type":[{"value":"1537-744X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012]]}}}