{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T20:24:43Z","timestamp":1770755083052,"version":"3.50.0"},"reference-count":11,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Scientific World Journal"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p><jats:italic>Purpose<\/jats:italic>. To present our results after short-term (1 month) intra-arterial infusion therapy of PGE<jats:sub>1<\/jats:sub>-alprostadil via a port system implanted in the ipsilateral external iliac artery (EIA) in patients with severe rest pain.<jats:italic>Methods<\/jats:italic>. Ten patients with severe rest pain were included. All patients showed extensive peripheral vascular disease below the knee. The tip of the catheter was introduced via a retrograde puncture in the ipsilateral external iliac artery (EIA). The patients received intraarterial infusion of PGE<jats:sub>1<\/jats:sub>, 20\u2009mgr alprostadil daily, via the port catheter for 1 month.<jats:italic>Results<\/jats:italic>. Clinical success was evaluated according to subjective grading of pain (group A significant decrease, group B moderate decrease and group C no response). A significant decrease of rest pain was observed in 8 (group A, 80%) patients, a moderate decrease in 2 (Group B, 20%), whereas no patients demonstrated any significant response. Both patients of group B had Buergers' disease and continue to smoke during therapy. No peripheral thrombosis or clinical deterioration was noticed.<jats:italic>Conclusion<\/jats:italic>. Intraarterial infusion of PGE<jats:sub>1<\/jats:sub>alprostadil on a daily basis, using a port catheter into the ipsilateral EIA, in selected patients with severe rest pain, seems to be very effective, without any serious complications.<\/jats:p>","DOI":"10.1100\/2012\/803678","type":"journal-article","created":{"date-parts":[[2012,3,12]],"date-time":"2012-03-12T22:02:34Z","timestamp":1331589754000},"page":"1-3","source":"Crossref","is-referenced-by-count":3,"title":["Intra-Arterial Prostaglandin E<sub>1<\/sub>Infusion in Patients with Rest Pain: Short-Term Results"],"prefix":"10.1100","volume":"2012","author":[{"given":"A.","family":"Chatziioannou","sequence":"first","affiliation":[{"name":"Department of Interventional Radiology, Aretaieion Hospital, University of Athens, 76 Vas. Sofias Avenue, 115 28 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Dalakidis","sequence":"additional","affiliation":[{"name":"Department of Interventional Radiology, Aretaieion Hospital, University of Athens, 76 Vas. Sofias Avenue, 115 28 Athens, Greece"},{"name":"Department of Radiology, Aretaieion Hospital, 76 Vas. Sofias, 115 28 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Katsenis","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, Aretaieion Hospital, Aretaieion Hospital, 76 Vas. Sofias Avenue, 115 28 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Koutoulidis","sequence":"additional","affiliation":[{"name":"Department of Interventional Radiology, Aretaieion Hospital, University of Athens, 76 Vas. Sofias Avenue, 115 28 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Mourikis","sequence":"additional","affiliation":[{"name":"Department of Interventional Radiology, Aretaieion Hospital, University of Athens, 76 Vas. 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