{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T01:30:43Z","timestamp":1648517443733},"reference-count":17,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Scientific World Journal"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. Due to the frequently interrupted supply of<jats:sup>99m<\/jats:sup>Tc-methylene diphosphonate, the use of<jats:sup>18<\/jats:sup>F-fluoride positron emission tomography (PET)\/computed tomography (CT) has become more popular. The study aims to determine the percentage of extraosseous findings from the unenhanced CT portion of<jats:sup>18<\/jats:sup>F-fluoride PET\/CT scans.<jats:italic>Materials and Methods<\/jats:italic>. We retrospectively collected<jats:sup>18<\/jats:sup>F-fluoride PET\/CT studies between March 2010 and February 2011. The unenhanced CT portions of<jats:sup>18<\/jats:sup>F-fluoride PET\/CT were reviewed for each patient. Significant extraosseous findings related to malignancy from the unenhanced CT were recorded.<jats:italic>Results<\/jats:italic>. A total of 158 patients (110 females, 48 males) were included in the study. Clinically significant extraosseous findings from the unenhanced CT were found in 43 patients (27.2%). Previously unknown extraosseous findings were identified in 17 patients (10.8%) after a review of the<jats:sup>18<\/jats:sup>F-fluoride PET\/CT scan results. Most of the extraosseous findings were small pulmonary metastases or enlarged metastatic lymph nodes.<jats:italic>Conclusion<\/jats:italic>. It is not rare to identify new clinically significant extraosseous findings from the unenhanced CT of<jats:sup>18<\/jats:sup>F-fluoride PET\/CT studies. Therefore the clinical management of patients may be altered by the results, and a careful review of the unenhanced CT portion of<jats:sup>18<\/jats:sup>F-fluoride PET\/CT is mandatory.<\/jats:p>","DOI":"10.1100\/2012\/979867","type":"journal-article","created":{"date-parts":[[2012,9,10]],"date-time":"2012-09-10T18:00:29Z","timestamp":1347300029000},"page":"1-5","source":"Crossref","is-referenced-by-count":2,"title":["Prevalence of Clinically Significant Extraosseous Findings on Unenhanced CT Portions of<sup>18<\/sup>F-Fluoride PET\/CT Bone Scans"],"prefix":"10.1100","volume":"2012","author":[{"given":"Chao-Jung","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Nuclear Medicine, Yuan's General Hospital, 162 Cheng-Kung 1st Road, Kaohsiung 802, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shih-Ya","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Yuan's General Hospital, 162 Cheng-Kung 1st Road, Kaohsiung 802, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.106.037200"},{"issue":"8","key":"2","first-page":"1352","volume":"46","year":"2005","journal-title":"Journal of Nuclear Medicine"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1007\/s10554-009-9490-x"},{"issue":"8","key":"4","first-page":"1312","volume":"47","year":"2006","journal-title":"Journal of Nuclear Medicine"},{"issue":"10","key":"5","first-page":"1623","volume":"40","year":"1999","journal-title":"Journal of Nuclear Medicine"},{"issue":"12","key":"6","first-page":"1800","volume":"42","year":"2001","journal-title":"Journal of Nuclear Medicine"},{"issue":"2","key":"7","first-page":"272","volume":"45","year":"2004","journal-title":"Journal of Nuclear Medicine"},{"issue":"2","key":"8","first-page":"287","volume":"47","year":"2006","journal-title":"Journal of Nuclear Medicine"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1097\/MNM.0b013e3283399120"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1016\/j.lungcan.2008.01.001"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2372041887"},{"issue":"1","key":"12","first-page":"45S","volume":"48","year":"2007","journal-title":"Journal of Nuclear Medicine"},{"issue":"10","key":"13","first-page":"1643","volume":"47","year":"2006","journal-title":"Journal of Nuclear Medicine"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.107.043109"},{"key":"15","first-page":"56S","volume":"45","year":"2004","journal-title":"Journal of Nuclear Medicine"},{"issue":"8","key":"16","first-page":"1249","volume":"46","year":"2005","journal-title":"Journal of Nuclear Medicine"},{"issue":"7","key":"17","first-page":"1225","volume":"46","year":"2005","journal-title":"Journal of Nuclear Medicine"}],"container-title":["The Scientific World Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/tswj\/2012\/979867.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/tswj\/2012\/979867.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/tswj\/2012\/979867.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,8,2]],"date-time":"2016-08-02T19:08:49Z","timestamp":1470164929000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/tswj\/2012\/979867\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":17,"alternative-id":["979867","979867"],"URL":"https:\/\/doi.org\/10.1100\/2012\/979867","relation":{},"ISSN":["1537-744X"],"issn-type":[{"value":"1537-744X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012]]}}}