{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T12:54:05Z","timestamp":1773924845068,"version":"3.50.1"},"reference-count":0,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2004,1,1]],"date-time":"2004-01-01T00:00:00Z","timestamp":1072915200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100003549","name":"Hungarian Scientific Research Fund","doi-asserted-by":"crossref","award":["T 034957"],"award-info":[{"award-number":["T 034957"]}],"id":[{"id":"10.13039\/501100003549","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100003549","name":"Hungarian Scientific Research Fund","doi-asserted-by":"crossref","award":["ETT 160\/2003"],"award-info":[{"award-number":["ETT 160\/2003"]}],"id":[{"id":"10.13039\/501100003549","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Hungarian Ministry of Health, Social and Family Affairs","award":["T 034957"],"award-info":[{"award-number":["T 034957"]}]},{"name":"Hungarian Ministry of Health, Social and Family Affairs","award":["ETT 160\/2003"],"award-info":[{"award-number":["ETT 160\/2003"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Scientific World JOURNAL"],"published-print":{"date-parts":[[2004]]},"abstract":"<jats:p>The main goal of this study was to evaluate the possible effect of whole-body magnetic field (MF) exposure on the steroidogenic capacity of Leydig cells<jats:italic>in vitro<\/jats:italic>. In four separate experiments, male CFLP mice were exposed to sinusoidal 50-Hz, 100-\u03bcT MF. The duration of exposure was 23.5 h\/day over a period of 14 days. At the end of the exposure, interstitial (Leydig) cells were isolated from the testicles of the sham-exposed and exposed animals. The cells were cultured for 48 h in the presence or absence of 1, 10, or 100 mIU\/ml human chorionic gonadotropin (hCG). The luteinizing hormone (LH) analog hCG was used to check the testosterone (T) response of the sham-exposed controls and to evaluate the possible effect of the whole-body MF exposure on the steroidogenic capacity of Leydig cells<jats:italic>in vitro<\/jats:italic>. Testosterone content of the culture media and blood sera was measured by radioimmunoassay (RIA). In the cultures obtained from MF-exposed animals, the hCG-stimulated T response was significanly higher (p &lt; 0.01) compared with the sham-exposed controls, while the basal T production of cells and the level of serum T remained unaltered. No MF exposure\u0096related histopathological alterations were found in testicles, epididymes, adrenals, prostates, and pituitary glands. The MF exposure did not affect the animal growth rate and the observed hematologic and serum chemical variables. Our results indicate a presumably direct effect of whole-body MF exposure on the hCG-stimulated steroidogenic response of mouse Leydig cells.<\/jats:p>","DOI":"10.1100\/tsw.2004.182","type":"journal-article","created":{"date-parts":[[2005,3,16]],"date-time":"2005-03-16T15:43:15Z","timestamp":1110987795000},"page":"83-90","source":"Crossref","is-referenced-by-count":17,"title":["Effects of Whole-Body 50-Hz Magnetic Field Exposure on Mouse Leydig Cells"],"prefix":"10.1100","volume":"4","author":[{"given":"Zsolt","family":"Forg\u00e1cs","sequence":"first","affiliation":[{"name":"National Institute of Chemical Safety, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zolt\u00e1n","family":"Somosy","sequence":"additional","affiliation":[{"name":"\u201cNational Frederic Joliot-Curie\u201d Research Institute for Radiobiology and Radiohygiene, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gy\u00f6rgyi","family":"Kubinyi","sequence":"additional","affiliation":[{"name":"\u201cNational Frederic Joliot-Curie\u201d Research Institute for Radiobiology and Radiohygiene, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanna","family":"Sinay","sequence":"additional","affiliation":[{"name":"\u201cNational Frederic Joliot-Curie\u201d Research Institute for Radiobiology and Radiohygiene, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jozsef","family":"Bakos","sequence":"additional","affiliation":[{"name":"\u201cNational Frederic Joliot-Curie\u201d Research Institute for Radiobiology and Radiohygiene, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gy\u00f6rgy","family":"Thur\u00f3czy","sequence":"additional","affiliation":[{"name":"\u201cNational Frederic Joliot-Curie\u201d Research Institute for Radiobiology and Radiohygiene, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e1s","family":"Surj\u00e1n","sequence":"additional","affiliation":[{"name":"National Institute of Chemical Safety, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aranka","family":"Hud\u00e1k","sequence":"additional","affiliation":[{"name":"Clinical Laboratory, National Institute of Occupational Health, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ferenc","family":"Olajos","sequence":"additional","affiliation":[{"name":"Second Department of Gynecology, Semmelweis University, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P\u00e9ter","family":"L\u00e1z\u00e1r","sequence":"additional","affiliation":[{"name":"National Institute of Chemical Safety, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","container-title":["The Scientific World JOURNAL"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/tswj\/2004\/108903.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/tswj\/2004\/108903.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,6]],"date-time":"2020-05-06T16:51:06Z","timestamp":1588783866000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/tswj\/2004\/108903\/abs\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004]]},"references-count":0,"alternative-id":["108903"],"URL":"https:\/\/doi.org\/10.1100\/tsw.2004.182","relation":{},"ISSN":["1537-744X"],"issn-type":[{"value":"1537-744X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004]]}}}