{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T21:54:07Z","timestamp":1791323647356,"version":"4.3.1"},"reference-count":0,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Scientific World JOURNAL"],"published-print":{"date-parts":[[2006]]},"abstract":"<jats:p>Rett syndrome (RS) is a neurological disorder affecting mainly females. RS is considered the second most frequent cause for severe and complex neurological dysfunction in females after Down syndrome. Patients with RS are characterized by an array of neurological and orthopedic difficulties that mandate an intensive therapeutic intervention program for the duration of the individual's life. Many aspects of the client\u0092s well-being and functional status depend on the therapeutic intervention she receives and on her compliance to it. This article will briefly review common intervention approaches for individuals with RS and their present day's application. Due to the notion that individual intervention is the foundation on which progress and development of the functional gains rests, the present article will place basic guidelines for individual intervention with clients with RS. The article is mainly based on the clinical experience of the author and others working with individuals with RS.<\/jats:p>","DOI":"10.1100\/tsw.2006.252","type":"journal-article","created":{"date-parts":[[2007,5,25]],"date-time":"2007-05-25T07:38:32Z","timestamp":1180078712000},"page":"1504-1516","source":"Crossref","is-referenced-by-count":18,"title":["Rett Syndrome. Guidelines for Individual Intervention"],"prefix":"10.1100","volume":"6","author":[{"given":"Meir","family":"Lotan","sequence":"first","affiliation":[{"name":"Israeli Rett Syndrome Association, National Rett Syndrome Clinic, Chaim Sheba Medical Center, Ramat-Gan, Israel"},{"name":"Zvi Quittman Residential Centers, Israel Elwyn, Jerusalem, Israel"},{"name":"Department of Physical Therapy, Academic College of Judea and Samaria, Ariel, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"98","container-title":["The Scientific World JOURNAL"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/tswj\/2006\/936460.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/tswj\/2006\/936460.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,8,23]],"date-time":"2016-08-23T12:09:10Z","timestamp":1471954150000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/tswj\/2006\/936460\/abs\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006]]},"references-count":0,"alternative-id":["936460"],"URL":"https:\/\/doi.org\/10.1100\/tsw.2006.252","relation":{},"ISSN":["1537-744X"],"issn-type":[{"value":"1537-744X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006]]}}}