{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T06:26:41Z","timestamp":1781677601431,"version":"3.54.5"},"reference-count":0,"publisher":"Wiley","license":[{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["5U10 CA11488-35"],"award-info":[{"award-number":["5U10 CA11488-35"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Scientific World JOURNAL"],"published-print":{"date-parts":[[2006]]},"abstract":"<jats:p>Superficial bladder cancer encompasses patients with stage Ta T1 tumors and patients with carcinoma<jats:italic>in situ<\/jats:italic>(CIS). The natural history or treatment-related prognosis of these patients varies considerably from one patient to the next based on the patient\u0092s clinical and the tumor's pathological characteristics. Based on a review of the literature, the most important prognostic factors for recurrence are the prior recurrence rate, number of tumors, and tumor size; whereas for progression, the most important prognostic factors are the T category, grade, and presence of CIS. Treatment with intravesical bacillus Calmette-Guerin reduces both the risk of recurrence and the risk of progression, and is the treatment of choice in high-risk papillary tumors and in patients with CIS. Assessment of a patient's prognostic factors and his or her risk of recurrence and progression is a prerequisite for determining the most appropriate treatment and frequency of follow-up for a given patient.<\/jats:p>","DOI":"10.1100\/tsw.2006.404","type":"journal-article","created":{"date-parts":[[2007,5,26]],"date-time":"2007-05-26T18:03:40Z","timestamp":1180202620000},"page":"2617-2625","source":"Crossref","is-referenced-by-count":69,"title":["Natural History, Recurrence, and Progression in Superficial Bladder Cancer"],"prefix":"10.1100","volume":"6","author":[{"given":"Richard J.","family":"Sylvester","sequence":"first","affiliation":[{"name":"European Organisation for Research and Treatment of Cancer Data Center, 83 avenue E Mounier, 1200 Brussels, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","container-title":["The Scientific World JOURNAL"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/tswj\/2006\/209043.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/tswj\/2006\/209043.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,8,23]],"date-time":"2016-08-23T03:43:18Z","timestamp":1471923798000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/tswj\/2006\/209043\/abs\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006]]},"references-count":0,"alternative-id":["209043"],"URL":"https:\/\/doi.org\/10.1100\/tsw.2006.404","relation":{},"ISSN":["1537-744X"],"issn-type":[{"value":"1537-744X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006]]}}}