{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T16:12:18Z","timestamp":1758816738909},"reference-count":0,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Scientific World JOURNAL"],"published-print":{"date-parts":[[2009]]},"abstract":"<jats:p>Transurethral needle ablation (TUNA) is an accepted and effective therapy for the treatment of lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH). Prostiva<jats:sup>TM<\/jats:sup>(Medtronic, Shoreview, MN) is the newest-generation device, which includes a new needle design and radio frequency (RF) generator. This device creates temperatures of 120\u00b0C and necrotic lesions in less than 2.5 min. Using previously described techniques, we analyzed dynamic, gadolinium-enhanced MRIs to characterize the ablative properties of the new Prostiva<jats:sup>TM<\/jats:sup>RF device.<\/jats:p><jats:p>Ten men with LUTS due to BPH were treated with the standard Prostiva<jats:sup>TM<\/jats:sup>manufacturer\u2013recommended protocol. The bladder neck and lateral lobes received treatment based on prostate volume and prostatic urethral length. Gadolinium-enhanced MRI sequences were obtained prior to and 1 week post-treatment. Analyze\u00ae software (Mayo Clinic Biomedical Imaging Resource, Rochester, MN) was used to evaluate MRIs. New gadolinium defects were seen in all patients following Prostiva<jats:sup>TM<\/jats:sup>treatments. All lesions coalesced within the prostate. No defects were seen beyond the prostate, and the urethra was spared in all patients. The mean volume of necrosis was 7.56 cc, representing a mean of 11.28% of total prostate volume.<\/jats:p><jats:p>Dynamic, gadolinium-enhanced MRIs demonstrate new vascular defects representing necrosis caused by Prostiva<jats:sup>TM<\/jats:sup>RF therapy of the prostate. The standard Prostiva<jats:sup>TM<\/jats:sup>RF protocol produces lesions that coalesce to create larger lesions in the bladder neck and lateral lobes. Compared to the TUNA\u00ae Precision Plus<jats:sup>TM<\/jats:sup>device, the ablative lesions appear comparable while produced with a shorter burn time.<\/jats:p>","DOI":"10.1100\/tsw.2009.4","type":"journal-article","created":{"date-parts":[[2011,8,15]],"date-time":"2011-08-15T10:05:29Z","timestamp":1313402729000},"page":"10-16","source":"Crossref","is-referenced-by-count":8,"title":["Characterizing Prostiva<sup>TM<\/sup>RF Treatments of the Prostate for BPH with Gadolinium-Enhanced MRI"],"prefix":"10.1100","volume":"9","author":[{"given":"Christian","family":"Huidobro","sequence":"first","affiliation":[{"name":"Department of Urology, University of Chile, Santiago, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin","family":"Larson","sequence":"additional","affiliation":[{"name":"Cleveland Clinic Lerner College of Medicine, Cleveland, OH, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel","family":"Mynderse","sequence":"additional","affiliation":[{"name":"Mayo Clinic Biomedical Imaging Resource, Rochester, MN, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James J.","family":"Myers","sequence":"additional","affiliation":[{"name":"Urologic Physicians, Minneapolis, MN, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Busel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristian","family":"Acevedo","sequence":"additional","affiliation":[{"name":"Department of Urology, University of Chile, Santiago, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thayne R.","family":"Larson","sequence":"additional","affiliation":[{"name":"Institute of Medical Research, Scottsdale, AZ, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lance A.","family":"Mynderse","sequence":"additional","affiliation":[{"name":"Department of Urology, Mayo Clinic, Rochester, MN, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","container-title":["The Scientific World JOURNAL"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/tswj\/2009\/624139.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/tswj\/2009\/624139.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,8,23]],"date-time":"2016-08-23T12:14:09Z","timestamp":1471954449000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/tswj\/2009\/624139\/abs\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009]]},"references-count":0,"alternative-id":["624139"],"URL":"https:\/\/doi.org\/10.1100\/tsw.2009.4","relation":{},"ISSN":["1537-744X"],"issn-type":[{"value":"1537-744X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009]]}}}