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In an olfactory functional magnetic resonance imaging (fMRI) study of twenty young healthy subjects with a normal sense of smell, we tested whether nostril specific stimulation with phenyl ethyl alcohol (PEA), a pure olfactory stimulant, asymmetrically activates primary or secondary olfactory-related brain structures such as primary olfactory cortex, entorhinal cortex, and orbitofrontal cortex. The results indicated that without a challenging olfactory task, passive (no sniffing) and active (with sniffing) nostril-specific PEA stimulation did not produce asymmetrical fMRI activation in olfactory cortical structures.<\/jats:p>","DOI":"10.1101\/2023.08.01.551475","type":"posted-content","created":{"date-parts":[[2023,8,3]],"date-time":"2023-08-03T20:45:29Z","timestamp":1691095529000},"source":"Crossref","is-referenced-by-count":4,"title":["Monorhinal and Birhinal Odor Processing in Humans: an fMRI investigation"],"prefix":"10.64898","author":[{"given":"Anupa","family":"Ekanayake","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qing","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sangam","family":"Kanekar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Biyar","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silas","family":"McCaslin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deepak","family":"Kalra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Eslinger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prasanna","family":"Karunanayaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"54368","reference":[{"key":"2023080507450737000_2023.08.01.551475v1.1","doi-asserted-by":"publisher","DOI":"10.1038\/360339a0"},{"key":"2023080507450737000_2023.08.01.551475v1.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2006.01.007"},{"key":"2023080507450737000_2023.08.01.551475v1.3","doi-asserted-by":"publisher","DOI":"10.1038\/nn.2324"},{"key":"2023080507450737000_2023.08.01.551475v1.4","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.22-24-10819.2002"},{"key":"2023080507450737000_2023.08.01.551475v1.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2009.09.066"},{"key":"2023080507450737000_2023.08.01.551475v1.6","doi-asserted-by":"publisher","DOI":"10.1016\/0278-2626(82)90028-8"},{"key":"2023080507450737000_2023.08.01.551475v1.7","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3106-08.2008"},{"key":"2023080507450737000_2023.08.01.551475v1.8","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1997.78.1.160"},{"key":"2023080507450737000_2023.08.01.551475v1.9","doi-asserted-by":"crossref","unstructured":"J. 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