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In contrast, a rumination-like signature emerged in the BLA of susceptible mice; a linear decoder could classify the intention to switch or stay on a previously chosen reward. Spontaneous activity in the BLA of susceptible mice was higher dimensional than controls, reflecting the exploration of a larger number of distinct neural states. Manipulation of vCA1-BLA inputs rescued dysfunctional neural dynamics and anhedonia in susceptible mice, suggesting that targeting this pathway can enhance BLA circuit function and ameliorate of depression-related behaviors.<\/jats:p>\n                <jats:sec>\n                  <jats:title>One-Sentence Summary<\/jats:title>\n                  <jats:p>Identification and rescue of dysfunctional vCA1-BLA population dynamics and behavior in stress-susceptible mice.<\/jats:p>\n                <\/jats:sec>","DOI":"10.1101\/2023.10.23.563652","type":"posted-content","created":{"date-parts":[[2023,10,24]],"date-time":"2023-10-24T11:45:27Z","timestamp":1698147927000},"source":"Crossref","is-referenced-by-count":3,"title":["Neural signatures of stress susceptibility and resilience in the amygdala-hippocampal network"],"prefix":"10.64898","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7415-6620","authenticated-orcid":false,"given":"Frances","family":"Xia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valeria","family":"Fascianelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina","family":"Vishwakarma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frances Grace","family":"Ghinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3035-6652","authenticated-orcid":false,"given":"Stefano","family":"Fusi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9157-7363","authenticated-orcid":false,"given":"Mazen A","family":"Kheirbek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"54368","reference":[{"key":"2023102807200435000_2023.10.23.563652v1.1","unstructured":"T. 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