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While atrial fibrillation, diabetes, hyperlipidemia, hypertension, and stroke were associated more strongly with AD prevalence than nighttime light intensity, nighttime light was more strongly associated with AD prevalence than alcohol abuse, chronic kidney disease, depression, heart failure, and obesity. Startlingly, nighttime light exposure more strongly associated with AD prevalence in those under the age of 65 than any other disease factor examined. These data indicate a need to investigate how nighttime light exposure influences AD pathogenesis.<\/jats:p>\n                <jats:sec>\n                  <jats:title>One-Sentence Summary<\/jats:title>\n                  <jats:p>There is a positive association between Alzheimer\u2019s disease prevalence and average outdoor nighttime light intensity in the United States.<\/jats:p>\n                <\/jats:sec>","DOI":"10.1101\/2024.02.14.24302831","type":"posted-content","created":{"date-parts":[[2024,2,15]],"date-time":"2024-02-15T16:50:11Z","timestamp":1708015811000},"source":"Crossref","is-referenced-by-count":2,"title":["Outdoor Nighttime Light Exposure (Light Pollution) is Associated with Alzheimer\u2019s Disease"],"prefix":"10.64898","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8010-0786","authenticated-orcid":false,"given":"Robin M","family":"Voigt","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bichun","family":"Ouyang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Keshavarzian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"54368","reference":[{"key":"2024021823400957000_2024.02.14.24302831v1.1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.j2856"},{"key":"2024021823400957000_2024.02.14.24302831v1.2","doi-asserted-by":"crossref","first-page":"igx034","DOI":"10.1093\/geroni\/igx034","article-title":"\u2018Arab American Cognitive Aging: Opportunities for Advancing Research on Alzheimer\u2019s Disease Disparities","volume":"1","year":"2017","journal-title":"Innov Aging"},{"key":"2024021823400957000_2024.02.14.24302831v1.3","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1007\/s11064-022-03817-4","article-title":"\u2018A Potential Link Between Visceral Obesity and Risk of Alzheimer\u2019s Disease","volume":"48","year":"2023","journal-title":"Neurochem Res"},{"key":"2024021823400957000_2024.02.14.24302831v1.4","doi-asserted-by":"publisher","DOI":"10.1111\/obr.12629"},{"key":"2024021823400957000_2024.02.14.24302831v1.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2019.09.086"},{"key":"2024021823400957000_2024.02.14.24302831v1.6","doi-asserted-by":"publisher","DOI":"10.1097\/JGP.0b013e3181a2fd07"},{"key":"2024021823400957000_2024.02.14.24302831v1.7","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2013.70"},{"key":"2024021823400957000_2024.02.14.24302831v1.8","unstructured":"Bowers, B. 1998. 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