{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"institution":[{"name":"medRxiv"}],"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T12:15:13Z","timestamp":1768565713626,"version":"3.49.0"},"posted":{"date-parts":[[2024,3,19]]},"group-title":"Health Informatics","reference-count":25,"publisher":"openRxiv","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"accepted":{"date-parts":[[2024,3,19]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>To synthesize discussions among sexual minority men and gender diverse (SMMGD) individuals on mpox, given limited representation of SMMGD voices in existing mpox literature.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>\n                    BERTopic (a topic modeling technique) was employed with human validations to analyze mpox-related tweets (\n                    <jats:italic>n<\/jats:italic>\n                    = 8,688; October 2020\u2014September 2022) from 2,326 self-identified SMMGD individuals in the U.S.; followed by content analysis and geographic analysis.\n                  <\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>\n                    BERTopic identified 11 topics: health activism (29.81%); mpox vaccination (25.81%) and adverse events (0.98%); sarcasm, jokes, emotional expressions (14.04%); COVID-19 and mpox (7.32%); government\/public health response (6.12%); mpox symptoms (2.74%); case reports (2.21%); puns on the virus\u2019 naming (i.e., monkeypox; 0.86%); media publicity (0.68%); mpox in children (0.67%). Mpox health activism negatively correlated with LGB social climate index at U.S. state level,\n                    <jats:italic>\u03c1<\/jats:italic>\n                    = -0.322,\n                    <jats:italic>p<\/jats:italic>\n                    = 0.031.\n                  <\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>SMMGD discussions on mpox encompassed utilitarian (e.g., vaccine access, case reports, mpox symptoms) and emotionally-charged themes\u2014advocating against homophobia, misinformation, and stigma. Mpox health activism was more prevalent in states with lower LGB social acceptance.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                  <jats:title>Public Health Implications<\/jats:title>\n                  <jats:p>Findings illuminate SMMGD engagement with mpox discourse, underscoring the need for more inclusive health communication strategies in infectious disease outbreaks to control associated stigma.<\/jats:p>\n                <\/jats:sec>","DOI":"10.1101\/2024.03.19.24304519","type":"posted-content","created":{"date-parts":[[2024,3,19]],"date-time":"2024-03-19T21:57:17Z","timestamp":1710885437000},"source":"Crossref","is-referenced-by-count":3,"title":["Health activism, vaccine, and mpox discourse: BERTopic based mixed-method analyses of tweets from sexual minority men and gender diverse (SMMGD) individuals in the U.S."],"prefix":"10.64898","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3197-1366","authenticated-orcid":false,"given":"Yunwen","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen","family":"O\u2019Connor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivan","family":"Flores","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4374-3280","authenticated-orcid":false,"given":"Carl T.","family":"Berdahl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan J.","family":"Urbanowicz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robin","family":"Stevens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 A.","family":"Bauermeister","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Graciela","family":"Gonzalez-Hernandez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"54368","reference":[{"key":"2024032204350682000_2024.03.19.24304519v1.1","unstructured":"The Lancet Infectious Diseases. Monkeypox: A neglected old foe. Published 2022. Accessed December 15, 2023. https:\/\/www.thelancet.com\/journals\/laninf\/article\/PIIS1473-3099(22)00377-2\/fulltext"},{"key":"2024032204350682000_2024.03.19.24304519v1.2","unstructured":"World Health Organization. WHO recommends new name for monkeypox disease. Published 2022. 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