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We developed slightly different procedures for the autosomal, X, Y, and Mitochondrial (MT) chromosomes. Some of these filters are specific to family data, but some can be used with any WGS data set. We also describe the procedure we use to construct linkage markers from the SNP sequence data and how we compute IBD values for use in linkage analysis.<\/jats:p>","DOI":"10.1101\/2024.05.23.595584","type":"posted-content","created":{"date-parts":[[2024,5,24]],"date-time":"2024-05-24T23:15:11Z","timestamp":1716592511000},"source":"Crossref","is-referenced-by-count":10,"title":["A Paradigm For Calling Sequence In Families: The Long Life Family Study"],"prefix":"10.64898","author":[{"given":"E. 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