{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"institution":[{"name":"medRxiv"}],"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T21:18:46Z","timestamp":1790889526555,"version":"4.1.0"},"posted":{"date-parts":[[2024,12,2]]},"group-title":"Public and Global Health","reference-count":30,"publisher":"openRxiv","license":[{"start":{"date-parts":[[2024,12,2]],"date-time":"2024-12-02T00:00:00Z","timestamp":1733097600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"accepted":{"date-parts":[[2024,12,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                <jats:sec>\n                  <jats:title>Introduction<\/jats:title>\n                  <jats:p>Rift Valley Fever (RVF) has caused outbreaks in Africa, impacting human health and animal trade. Recently, sporadic detections among humans and animals in East Africa have replaced large-scale outbreaks. We assessed RVF knowledge levels in East and Central Africa across countries with different epidemiological profiles.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                  <jats:title>Materials and Methods<\/jats:title>\n                  <jats:p>Individuals aged \u226510 years with acute febrile illness were enrolled from six health facilities in Kenya, Uganda, and the Democratic Republic of Congo (DRC). Sociodemographic information was collected and participants asked questions on RVF transmission, symptoms, prevention, and control. Blood samples were tested for anti-RVF antibodies (IgG and IgM). Knowledge was categorized as absent, basic, or advanced. Descriptive and ordinal logistic regression analysis identified factors associated with RVF knowledge.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Among 4,806 participants (median age 31, IQR 22\u201344, 57.5% female), only 20.5% demonstrated any RVF knowledge (16.4% basic, 4.1% advanced). Knowledge levels varied by country: DRC (3.1%), Uganda (16.1%), and Kenya (42.6%). Factors associated with RVF knowledge included age 20\u201340 years aOR 1.72 (95%CI 1,24\u20132.22) and &gt;40 years 2.42 (95%CI 1.74\u20133.420), male gender aOR 1.54 (95%CI 1.31\u20131.82), healthcare workers aOR 7.95 (95%CI 5.25\u201312.1), residence in Kenya aOR 23.5 (95%CI 15.8\u201335.8) or Uganda 5.4 (95%CI 3.68\u20138.38), completing primary education aOR 3.24 (95%CI 1.94\u20135.75) with advanced education shown to increase knowledge, postgraduate aOR 11.5 (95%CI 4.0\u2013 32.4). Other factors included presence of livestock within the homes aOR 1.30 (95%CI 1.06\u2013 1.59) and prevention of mosquito bites aOR 1.55 (95%CI 0.46\u20130.66). Animal farmers, butchers, and those with close animal contact showed no association, despite being at-risk populations.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>RVF knowledge was low overall, varying by country, age, education, and environmental factors. Increased awareness is crucial for high-exposure groups in all regions, particularly in Uganda, where exposure is higher, but knowledge remains low.<\/jats:p>\n                <\/jats:sec>","DOI":"10.1101\/2024.12.02.24318288","type":"posted-content","created":{"date-parts":[[2024,12,2]],"date-time":"2024-12-02T13:30:58Z","timestamp":1733146258000},"source":"Crossref","is-referenced-by-count":2,"title":["Have you heard of Rift Valley fever? Findings from a multi-country study in East and Central Africa"],"prefix":"10.64898","author":[{"given":"Raymond","family":"Odinoh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeanette","family":"Dawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Situma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luke","family":"Nyakarahuka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luciana","family":"Lepore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veerle","family":"Vanlerberghe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolyne","family":"Nasimiyu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheila","family":"Makiala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Ifufa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Mukadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herve","family":"Viala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Owor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barnabas","family":"Bakamutumaho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deo","family":"Ndumu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin","family":"Masumu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert F.","family":"Breiman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kariuki","family":"Njenga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"54368","reference":[{"key":"2024120400400492000_2024.12.02.24318288v1.1","doi-asserted-by":"publisher","DOI":"10.1051\/vetres\/2010033"},{"key":"2024120400400492000_2024.12.02.24318288v1.2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2010.09-0288"},{"key":"2024120400400492000_2024.12.02.24318288v1.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.coviro.2012.02.017"},{"key":"2024120400400492000_2024.12.02.24318288v1.4","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2010.09-0293"},{"key":"2024120400400492000_2024.12.02.24318288v1.5","doi-asserted-by":"publisher","DOI":"10.3402\/iee.v5.28024"},{"key":"2024120400400492000_2024.12.02.24318288v1.6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2018.11.029"},{"key":"2024120400400492000_2024.12.02.24318288v1.7","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.22-0410"},{"key":"2024120400400492000_2024.12.02.24318288v1.8","doi-asserted-by":"publisher","DOI":"10.4102\/ojvr.v86i1.1737"},{"key":"2024120400400492000_2024.12.02.24318288v1.9","doi-asserted-by":"publisher","DOI":"10.1007\/s11250-018-1721-5"},{"key":"2024120400400492000_2024.12.02.24318288v1.10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2017.01.016"},{"key":"2024120400400492000_2024.12.02.24318288v1.11","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2010.09-0291"},{"key":"2024120400400492000_2024.12.02.24318288v1.12","doi-asserted-by":"crossref","unstructured":"A. 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