{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"institution":[{"name":"bioRxiv"}],"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T23:37:09Z","timestamp":1768520229862,"version":"3.49.0"},"posted":{"date-parts":[[2024,12,16]]},"group-title":"Genomics","reference-count":14,"publisher":"openRxiv","license":[{"start":{"date-parts":[[2024,12,16]],"date-time":"2024-12-16T00:00:00Z","timestamp":1734307200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"accepted":{"date-parts":[[2024,12,16]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                <jats:p>\n                  <jats:italic>Candida auris<\/jats:italic>\n                  poses a significant global health threat due to its multidrug-resistance and outbreak potential. In this study, we report its emergence in Minas Gerais, Brazil, supported by genomic surveillance that identified Clade-IV isolates, suggested a potential introduction from Colombia, and detected a missense mutation associated with azole resistance.\n                <\/jats:p>","DOI":"10.1101\/2024.12.13.627932","type":"posted-content","created":{"date-parts":[[2024,12,18]],"date-time":"2024-12-18T18:46:44Z","timestamp":1734547604000},"source":"Crossref","is-referenced-by-count":1,"title":["Emergence of\n                  <i>Candida auris<\/i>\n                  in Minas Gerais, Brazil: Genomic Surveillance to inform Rapid Public Health Responses"],"prefix":"10.64898","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1477-5558","authenticated-orcid":false,"given":"Luiz Marcelo Ribeiro","family":"Tom\u00e9","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dhian Renato Almeida","family":"Camargo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafael Wesley","family":"Bastos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara C\u00e2ndida Ferreira","family":"dos Santos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nat\u00e1lia Rocha","family":"Guimar\u00e3es","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00edlvia Helena Sousa Pietra","family":"Pedroso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo Eduardo","family":"de Souza da Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arist\u00f3teles","family":"G\u00f3es-Neto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lida Jouca","family":"de Assis Figueredo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriella","family":"da C\u00f4rte Castro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Maria Ribeiro Nunes","family":"Rodrigues","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Flavia Ribeiro Soares","family":"Cruzeiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N\u00e1dia Aparecida Campos","family":"Dutra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josiane Barbosa Piedade","family":"Moura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Glauco","family":"de Carvalho Pereira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmem Dolores","family":"Faria","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Giovanetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felipe Campos","family":"de Melo Iani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luiz Carlos J\u00fanior","family":"Alcantara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Talita \u00c9mile Ribeiro","family":"Adelino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"54368","reference":[{"key":"2024122100262638000_2024.12.13.627932v1.1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1348-0421.2008.00083.x"},{"key":"2024122100262638000_2024.12.13.627932v1.2","doi-asserted-by":"crossref","unstructured":"Schutz K , Melie T , Smith SD , Quandt CA . Patterns recovered in phylogenomic analysis of Candida auris and close relatives implicate broad environmental flexibility in Candida\/Clavispora clade yeasts. Microb Genom. 17 de abril de 2024;10(4).","DOI":"10.1099\/mgen.0.001233"},{"key":"2024122100262638000_2024.12.13.627932v1.3","doi-asserted-by":"publisher","DOI":"10.1016\/S2666-5247(24)00101-0"},{"key":"2024122100262638000_2024.12.13.627932v1.4","doi-asserted-by":"crossref","unstructured":"Chow NA , Mu\u00f1oz JF , Gade L , Berkow EL , Li X , Welsh RM , et al. Tracing the Evolutionary History and Global Expansion of Candida auris Using Population Genomic Analyses. mBio. 28 de abril de 2020;11(2).","DOI":"10.1128\/mBio.03364-19"},{"key":"2024122100262638000_2024.12.13.627932v1.5","doi-asserted-by":"publisher","DOI":"10.3390\/jof7030220"},{"key":"2024122100262638000_2024.12.13.627932v1.6","doi-asserted-by":"publisher","DOI":"10.1007\/s11046-021-00593-7"},{"key":"2024122100262638000_2024.12.13.627932v1.7","doi-asserted-by":"crossref","unstructured":"Spruijtenburg B , Nobrega de Almeida J\u00fanior J , Ribeiro F de C , Kemmerich KK , Baeta K , Meijer EFJ , et al. Multicenter Candida auris outbreak caused by azole\u2010susceptible clade <scp>IV<\/scp> in Pernambuco, Brazil. Mycoses. 16 de junho de 2024;67(6).","DOI":"10.1111\/myc.13752"},{"key":"2024122100262638000_2024.12.13.627932v1.8","unstructured":"Anvisa (https:\/\/www.gov.br\/anvisa\/). https:\/\/www.gov.br\/anvisa\/. 2023. p. 1\u20135 Alerta de Risco GVIMS\/GGTES\/Anvisa no 01\/2023: Confirma\u00e7\u00e3o de caso de Candida auris em Hospital de S\u00e3o Paulo."},{"key":"2024122100262638000_2024.12.13.627932v1.9","unstructured":"CDC: Centers for Disease Control and Prevention. https:\/\/www.cdc.gov\/candida-auris\/hcp\/laboratories\/real-time-pcr-identification.html. 2024. Candida auris (C. auris) - Real-Time PCR Based Identification."},{"key":"2024122100262638000_2024.12.13.627932v1.10","doi-asserted-by":"crossref","unstructured":"Prjibelski A , Antipov D , Meleshko D , Lapidus A , Korobeynikov A. Using SPAdes De Novo Assembler. 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