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However, their effectiveness is limited because they do not adequately restore the acoustic cues essential for sound localization, particularly interaural time differences (ITDs) at low frequencies. The cochlea, the auditory sensory organ, typically transmits ITDs more effectively at the apical region, which is specifically \"tuned\" to low frequencies. We hypothesized that effective restoration of robust ITD perception through electrical stimulation with BiCIs depends on targeting cochlear locations that transmit information most effectively. Importantly, we show that these locations can occur anywhere along the cochlea, even on the opposite end of the frequency map from where ITD cues are most dominantly encoded in an acoustic hearing system.<\/jats:p>","DOI":"10.1101\/2024.12.27.627652","type":"posted-content","created":{"date-parts":[[2024,12,27]],"date-time":"2024-12-27T18:30:12Z","timestamp":1735324212000},"source":"Crossref","is-referenced-by-count":1,"title":["Best Cochlear Locations for Delivering Interaural Timing Cues in Electric Hearing"],"prefix":"10.64898","author":[{"given":"Agudemu","family":"Borjigin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen R.","family":"Dennison","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanvi","family":"Thakkar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan","family":"Kan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruth Y.","family":"Litovsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"54368","reference":[{"key":"2024122822000804000_2024.12.27.627652v1.1","doi-asserted-by":"publisher","DOI":"10.1121\/1.5130384"},{"key":"2024122822000804000_2024.12.27.627652v1.2","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2022.1018190"},{"key":"2024122822000804000_2024.12.27.627652v1.3","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0263516"},{"key":"2024122822000804000_2024.12.27.627652v1.4","doi-asserted-by":"publisher","DOI":"10.1121\/1.3298451"},{"key":"2024122822000804000_2024.12.27.627652v1.5","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2020.00915"},{"key":"2024122822000804000_2024.12.27.627652v1.6","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e3180430179"},{"key":"2024122822000804000_2024.12.27.627652v1.7","doi-asserted-by":"publisher","DOI":"10.1121\/1.3641400"},{"key":"2024122822000804000_2024.12.27.627652v1.8","doi-asserted-by":"crossref","unstructured":"Blauert, J . 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