{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"institution":[{"name":"medRxiv"}],"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T12:39:39Z","timestamp":1768567179736,"version":"3.49.0"},"posted":{"date-parts":[[2025,2,27]]},"group-title":"Infectious Diseases (except HIV\/AIDS)","reference-count":11,"publisher":"openRxiv","license":[{"start":{"date-parts":[[2025,2,27]],"date-time":"2025-02-27T00:00:00Z","timestamp":1740614400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"accepted":{"date-parts":[[2025,4,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                <jats:p>\n                  Interpretation of sero-epidemiology studies of cholera relies on knowledge of\n                  <jats:italic>Vibrio cholerae<\/jats:italic>\n                  antibody kinetics, which thus far have been lacking in African populations. We performed vibriocidal assays on 212 serum samples from 116 culture-positive cholera patients (median age 8 (IQR 4-18)) in Goma, DRC, collected at enrollment and again 3-449 days after. Vibriocidal responses peaked 7-40 days after symptom onset, with nearly all samples declining to a titer of 160 or lower by day 180. We used a Bayesian exponential decay model to show an 88% probability of a faster decay in children under 5.\n                <\/jats:p>","DOI":"10.1101\/2025.02.26.25322966","type":"posted-content","created":{"date-parts":[[2025,2,27]],"date-time":"2025-02-27T22:50:16Z","timestamp":1740696616000},"source":"Crossref","is-referenced-by-count":1,"title":["Longterm kinetics of vibriocidal antibody responses after\n                  <i>V. cholerae<\/i>\n                  infection in the Democratic Republic of Congo"],"prefix":"10.64898","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-5198-9099","authenticated-orcid":false,"given":"Kilee L.","family":"Davis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmen","family":"Nieznanski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felicien","family":"Maisha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ben J.","family":"Brintz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6236-5636","authenticated-orcid":false,"given":"Christy","family":"Clutter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meer","family":"Alam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cyrus","family":"Saleem","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Afsar","family":"Ali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. 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