{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"institution":[{"name":"medRxiv"}],"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T14:19:38Z","timestamp":1768573178107,"version":"3.49.0"},"posted":{"date-parts":[[2025,11,9]]},"group-title":"Infectious Diseases (except HIV\/AIDS)","reference-count":20,"publisher":"openRxiv","license":[{"start":{"date-parts":[[2025,11,9]],"date-time":"2025-11-09T00:00:00Z","timestamp":1762646400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"accepted":{"date-parts":[[2025,11,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                <jats:p>\n                  Among patients with primary syphilis, sensitivity of TRUST was 55% (6\/11) compared to darkfield microscopy (DFM) and 60% (9\/15) compared to\n                  <jats:italic>Treponema pallidum<\/jats:italic>\n                  PCR. Sensitivity of RPR was 78% (38\/49) and 93% (43\/46), respectively. TPPA had a sensitivity of 95% (41\/43) compared to DFM and 96% (43\/45) compared to PCR.\n                <\/jats:p>\n                <jats:sec>\n                  <jats:title>Short Summary<\/jats:title>\n                  <jats:p>Compared to direct detection methods for the diagnosis of primary syphilis, TRUST has low sensitivity, RPR has moderate to good sensitivity, and TPPA has high sensitivity.<\/jats:p>\n                <\/jats:sec>","DOI":"10.1101\/2025.11.07.25339586","type":"posted-content","created":{"date-parts":[[2025,11,9]],"date-time":"2025-11-09T18:55:12Z","timestamp":1762714512000},"source":"Crossref","is-referenced-by-count":0,"title":["Estimating the sensitivity of non-treponemal and treponemal antibody tests in primary syphilis"],"prefix":"10.64898","author":[{"given":"Stephanie F.","family":"Sweitzer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jane 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