{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T23:29:33Z","timestamp":1791674973417,"version":"4.3.4"},"reference-count":63,"publisher":"Cold Spring Harbor Laboratory","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cold Spring Harb Perspect Med"],"published-print":{"date-parts":[[2021,3]]},"DOI":"10.1101\/cshperspect.a038877","type":"journal-article","created":{"date-parts":[[2020,3,9]],"date-time":"2020-03-09T16:35:14Z","timestamp":1583771714000},"page":"a038877","source":"Crossref","is-referenced-by-count":25,"title":["Family-Based Designs that Disentangle Inherited Factors from Pre- and Postnatal Environmental Exposures: In Vitro Fertilization, Discordant Sibling Pairs, Maternal versus Paternal Comparisons, and Adoption Designs"],"prefix":"10.1101","volume":"11","author":[{"given":"Anita","family":"Thapar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frances","family":"Rice","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"246","published-online":{"date-parts":[[2020,3,9]]},"reference":[{"key":"2021052707051662000_11.3.a038877.1","unstructured":"Academy of Medical Sciences. 2007. Identifying the environmental causes of disease: how should we decide what to believe and when to take action? https:\/\/acmedsci.ac.uk\/file-download\/34654-119615475058.pdf"},{"key":"2021052707051662000_11.3.a038877.2","doi-asserted-by":"publisher","DOI":"10.1097\/EDE.0b013e318245912c"},{"key":"2021052707051662000_11.3.a038877.3","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddz204"},{"key":"2021052707051662000_11.3.a038877.4","doi-asserted-by":"publisher","DOI":"10.1007\/s10519-015-9738-2"},{"key":"2021052707051662000_11.3.a038877.5","doi-asserted-by":"publisher","DOI":"10.1001\/archgenpsychiatry.2010.33"},{"key":"2021052707051662000_11.3.a038877.6","doi-asserted-by":"publisher","DOI":"10.1111\/cdep.12078"},{"key":"2021052707051662000_11.3.a038877.7","doi-asserted-by":"publisher","DOI":"10.1093\/ntr\/ntx001"},{"key":"2021052707051662000_11.3.a038877.8","doi-asserted-by":"publisher","DOI":"10.1097\/EDE.0b013e31825fa230"},{"key":"2021052707051662000_11.3.a038877.9","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-psych-122414-033352"},{"key":"2021052707051662000_11.3.a038877.10","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2013.127"},{"key":"2021052707051662000_11.3.a038877.11","doi-asserted-by":"publisher","DOI":"10.1037\/0012-1649.32.4.574"},{"key":"2021052707051662000_11.3.a038877.12","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.2006.102772"},{"key":"2021052707051662000_11.3.a038877.13","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwn175"},{"key":"2021052707051662000_11.3.a038877.14","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291714001524"},{"key":"2021052707051662000_11.3.a038877.15","doi-asserted-by":"publisher","DOI":"10.1016\/j.copsyc.2017.02.004"},{"key":"2021052707051662000_11.3.a038877.16","doi-asserted-by":"publisher","DOI":"10.1111\/1469-7610.00123"},{"key":"2021052707051662000_11.3.a038877.17","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2016-2509"},{"key":"2021052707051662000_11.3.a038877.18","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291710001753"},{"key":"2021052707051662000_11.3.a038877.19","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2017-2465"},{"key":"2021052707051662000_11.3.a038877.20","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a039503"},{"key":"2021052707051662000_11.3.a038877.21","doi-asserted-by":"publisher","DOI":"10.1016\/j.mppsy.2008.10.002"},{"key":"2021052707051662000_11.3.a038877.22","doi-asserted-by":"publisher","DOI":"10.1001\/jama.294.21.2751"},{"key":"2021052707051662000_11.3.a038877.23","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291706009524"},{"key":"2021052707051662000_11.3.a038877.24","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1417106112"},{"key":"2021052707051662000_11.3.a038877.25","doi-asserted-by":"publisher","DOI":"10.1097\/EDE.0b013e31828c7381"},{"key":"2021052707051662000_11.3.a038877.26","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291713000986"},{"key":"2021052707051662000_11.3.a038877.27","doi-asserted-by":"publisher","DOI":"10.1126\/science.aan6877"},{"key":"2021052707051662000_11.3.a038877.28","doi-asserted-by":"publisher","DOI":"10.1007\/s00787-014-0641-9"},{"key":"2021052707051662000_11.3.a038877.29","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwr510"},{"key":"2021052707051662000_11.3.a038877.30","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyw314"},{"key":"2021052707051662000_11.3.a038877.31","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaac.2011.01.015"},{"key":"2021052707051662000_11.3.a038877.32","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2016.4257"},{"key":"2021052707051662000_11.3.a038877.33","doi-asserted-by":"publisher","DOI":"10.1007\/s10802-017-0320-7"},{"key":"2021052707051662000_11.3.a038877.34","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.61.8.836"},{"key":"2021052707051662000_11.3.a038877.35","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a039552"},{"key":"2021052707051662000_11.3.a038877.36","doi-asserted-by":"publisher","DOI":"10.1111\/jcpp.12478"},{"key":"2021052707051662000_11.3.a038877.37","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2016.16020138"},{"key":"2021052707051662000_11.3.a038877.38","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2014-004915"},{"key":"2021052707051662000_11.3.a038877.39","doi-asserted-by":"publisher","DOI":"10.1097\/EDE.0000000000001108"},{"key":"2021052707051662000_11.3.a038877.40","doi-asserted-by":"publisher","DOI":"10.1038\/s41576-018-0020-3"},{"key":"2021052707051662000_11.3.a038877.41","unstructured":"Plomin R . 2018. Blueprint: how DNA makes us who we are. Allen Lane, London."},{"key":"2021052707051662000_11.3.a038877.42","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.2006.00895.x"},{"key":"2021052707051662000_11.3.a038877.43","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0808798106"},{"key":"2021052707051662000_11.3.a038877.44","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291709005911"},{"key":"2021052707051662000_11.3.a038877.45","doi-asserted-by":"publisher","DOI":"10.1017\/S0954579412000880"},{"key":"2021052707051662000_11.3.a038877.46","doi-asserted-by":"publisher","DOI":"10.1017\/S0954579418000421"},{"key":"2021052707051662000_11.3.a038877.47","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2017.08.014"},{"key":"2021052707051662000_11.3.a038877.48","doi-asserted-by":"publisher","DOI":"10.1037\/0033-2909.127.3.291"},{"key":"2021052707051662000_11.3.a038877.49","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7610.2005.01557.x"},{"key":"2021052707051662000_11.3.a038877.50","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyx213"},{"key":"2021052707051662000_11.3.a038877.51","doi-asserted-by":"publisher","DOI":"10.1177\/0165025409338444"},{"key":"2021052707051662000_11.3.a038877.52","doi-asserted-by":"publisher","DOI":"10.1111\/jcpp.12124"},{"key":"2021052707051662000_11.3.a038877.53","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2013.1951"},{"key":"2021052707051662000_11.3.a038877.54","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2018-3144"},{"key":"2021052707051662000_11.3.a038877.55","doi-asserted-by":"publisher","DOI":"10.1001\/jama.294.5.557"},{"key":"2021052707051662000_11.3.a038877.56","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.3413"},{"key":"2021052707051662000_11.3.a038877.57","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1996.01830010027005"},{"key":"2021052707051662000_11.3.a038877.58","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.109.062828"},{"key":"2021052707051662000_11.3.a038877.59","doi-asserted-by":"crossref","unstructured":"Thapar A , Rutter M . 2015. Using natural experiments and animal models to study causal hypotheses in relation to child mental health problems. In Rutter's child and adolescent psychiatry, 6th ed. (ed. Pine DS , ), pp. 145\u2013162. Wiley, Somerset, NJ.","DOI":"10.1002\/9781118381953.ch12"},{"key":"2021052707051662000_11.3.a038877.60","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291718003896"},{"key":"2021052707051662000_11.3.a038877.61","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2288-7-25"},{"key":"2021052707051662000_11.3.a038877.62","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2009.05.032"},{"key":"2021052707051662000_11.3.a038877.63","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2008.07091438"}],"container-title":["Cold Spring Harbor Perspectives in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1101\/cshperspect.a038877","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,27]],"date-time":"2021-05-27T14:10:57Z","timestamp":1622124657000},"score":1,"resource":{"primary":{"URL":"http:\/\/perspectivesinmedicine.cshlp.org\/lookup\/doi\/10.1101\/cshperspect.a038877"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,9]]},"references-count":63,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2021,3,1]]},"published-print":{"date-parts":[[2021,3]]}},"alternative-id":["10.1101\/cshperspect.a038877"],"URL":"https:\/\/doi.org\/10.1101\/cshperspect.a038877","relation":{},"ISSN":["2157-1422"],"issn-type":[{"value":"2157-1422","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3,9]]}}}