{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T06:23:17Z","timestamp":1790835797543,"version":"4.1.0"},"reference-count":310,"publisher":"Cold Spring Harbor Laboratory","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cold Spring Harb Perspect Biol"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1101\/cshperspect.a041773","type":"journal-article","created":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T18:15:16Z","timestamp":1766168116000},"page":"a041773","source":"Crossref","is-referenced-by-count":4,"title":["Mitochondrial Calcium Signaling in Hepatocyte Health and Disease"],"prefix":"10.1101","volume":"18","author":[{"given":"David R.","family":"Eberhardt","sequence":"first","affiliation":[{"name":"Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, Utah 84132, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0605-7334","authenticated-orcid":false,"given":"Dipayan","family":"Chaudhuri","sequence":"additional","affiliation":[{"name":"Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, Utah 84132, USA"},{"name":"Division of Cardiovascular Medicine, Department of Internal Medicine, Biochemistry, Biomedical Engineering, University of Utah, Salt Lake City, Utah 84112, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"246","published-online":{"date-parts":[[2025,12,19]]},"reference":[{"key":"2026030208250822000_18.3.a041773.1","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.2011.55"},{"key":"2026030208250822000_18.3.a041773.2","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2021.629522"},{"key":"2026030208250822000_18.3.a041773.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceca.2014.11.002"},{"key":"2026030208250822000_18.3.a041773.4","doi-asserted-by":"publisher","DOI":"10.1002\/hep.32562"},{"key":"2026030208250822000_18.3.a041773.5","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.49150"},{"key":"2026030208250822000_18.3.a041773.6","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.RA119.012361"},{"key":"2026030208250822000_18.3.a041773.7","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2021.641194"},{"key":"2026030208250822000_18.3.a041773.8","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.123.045550"},{"key":"2026030208250822000_18.3.a041773.9","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2021.108873"},{"key":"2026030208250822000_18.3.a041773.10","doi-asserted-by":"publisher","DOI":"10.26508\/lsa.201900491"},{"key":"2026030208250822000_18.3.a041773.11","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2021.110139"},{"key":"2026030208250822000_18.3.a041773.12","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3735"},{"key":"2026030208250822000_18.3.a041773.13","doi-asserted-by":"publisher","DOI":"10.1177\/25152564231181020"},{"key":"2026030208250822000_18.3.a041773.14","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2017.00839"},{"key":"2026030208250822000_18.3.a041773.15","doi-asserted-by":"publisher","DOI":"10.15252\/embr.202254978"},{"key":"2026030208250822000_18.3.a041773.16","doi-asserted-by":"publisher","DOI":"10.3390\/ijms17091558"},{"key":"2026030208250822000_18.3.a041773.17","doi-asserted-by":"publisher","DOI":"10.1002\/hep.510280521"},{"key":"2026030208250822000_18.3.a041773.18","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-30236-4"},{"key":"2026030208250822000_18.3.a041773.19","doi-asserted-by":"crossref","unstructured":"Balderas E , Sommakia S , Eberhardt D , Lee S , Chaudhuri D . 2023. The structural era of the mitochondrial calcium uniporter. In Calcium signals (ed. Satin LS , Ben-Johny M , Dick IE ), pp. 12\u201322. IOP, Bristol, UK.","DOI":"10.1088\/978-0-7503-2009-2ch12"},{"key":"2026030208250822000_18.3.a041773.20","doi-asserted-by":"publisher","DOI":"10.1152\/physiol.00014.2024"},{"key":"2026030208250822000_18.3.a041773.21","doi-asserted-by":"publisher","DOI":"10.1038\/s41388-019-0772-z"},{"key":"2026030208250822000_18.3.a041773.22","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceca.2020.102343"},{"key":"2026030208250822000_18.3.a041773.23","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceca.2014.02.007"},{"key":"2026030208250822000_18.3.a041773.24","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-11646-3"},{"key":"2026030208250822000_18.3.a041773.25","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceca.2020.102186"},{"key":"2026030208250822000_18.3.a041773.26","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbalip.2021.159030"},{"key":"2026030208250822000_18.3.a041773.27","doi-asserted-by":"publisher","DOI":"10.1038\/nature10234"},{"key":"2026030208250822000_18.3.a041773.28","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M109.025353"},{"key":"2026030208250822000_18.3.a041773.29","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2022.03.017"},{"key":"2026030208250822000_18.3.a041773.30","doi-asserted-by":"publisher","DOI":"10.1042\/bj2310439"},{"key":"2026030208250822000_18.3.a041773.31","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.106976.1"},{"key":"2026030208250822000_18.3.a041773.32","doi-asserted-by":"publisher","DOI":"10.1016\/S0005-2728(00)00254-1"},{"key":"2026030208250822000_18.3.a041773.33","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamcr.2025.119954"},{"key":"2026030208250822000_18.3.a041773.34","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibs.2009.03.006"},{"key":"2026030208250822000_18.3.a041773.35","doi-asserted-by":"publisher","DOI":"10.1038\/s41556-019-0329-y"},{"key":"2026030208250822000_18.3.a041773.36","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-024-05286-0"},{"key":"2026030208250822000_18.3.a041773.37","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0168328"},{"key":"2026030208250822000_18.3.a041773.38","doi-asserted-by":"publisher","DOI":"10.15252\/embr.202051954"},{"key":"2026030208250822000_18.3.a041773.39","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0808249105"},{"key":"2026030208250822000_18.3.a041773.40","doi-asserted-by":"publisher","DOI":"10.1002\/hep.24377"},{"key":"2026030208250822000_18.3.a041773.41","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201709111"},{"key":"2026030208250822000_18.3.a041773.42","doi-asserted-by":"publisher","DOI":"10.7570\/jomes23052"},{"key":"2026030208250822000_18.3.a041773.43","doi-asserted-by":"publisher","DOI":"10.3390\/cells12162017"},{"key":"2026030208250822000_18.3.a041773.44","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.00704"},{"key":"2026030208250822000_18.3.a041773.45","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1602264113"},{"key":"2026030208250822000_18.3.a041773.46","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.274.9.5692"},{"key":"2026030208250822000_18.3.a041773.47","doi-asserted-by":"publisher","DOI":"10.1186\/s12964-024-01829-x"},{"key":"2026030208250822000_18.3.a041773.48","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2017.00078"},{"key":"2026030208250822000_18.3.a041773.49","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200604016"},{"key":"2026030208250822000_18.3.a041773.50","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2013.04.020"},{"key":"2026030208250822000_18.3.a041773.51","doi-asserted-by":"publisher","DOI":"10.1177\/25152564241229273"},{"key":"2026030208250822000_18.3.a041773.52","first-page":"6674","article-title":"The bioenergetic signature of cancer: a marker of tumor progression","volume":"62","year":"2002","journal-title":"Cancer Res"},{"key":"2026030208250822000_18.3.a041773.53","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvad169"},{"key":"2026030208250822000_18.3.a041773.54","doi-asserted-by":"publisher","DOI":"10.1007\/s00424-012-1100-4"},{"key":"2026030208250822000_18.3.a041773.55","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceca.2014.03.004"},{"key":"2026030208250822000_18.3.a041773.56","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2002.35952"},{"key":"2026030208250822000_18.3.a041773.57","doi-asserted-by":"publisher","DOI":"10.7150\/ijbs.41768"},{"key":"2026030208250822000_18.3.a041773.58","doi-asserted-by":"publisher","DOI":"10.1038\/nature10189"},{"key":"2026030208250822000_18.3.a041773.59","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbabio.2009.01.005"},{"key":"2026030208250822000_18.3.a041773.60","doi-asserted-by":"publisher","DOI":"10.1038\/nature10230"},{"key":"2026030208250822000_18.3.a041773.61","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00334.2019"},{"key":"2026030208250822000_18.3.a041773.62","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22105375"},{"key":"2026030208250822000_18.3.a041773.63","doi-asserted-by":"publisher","DOI":"10.1111\/febs.70184"},{"key":"2026030208250822000_18.3.a041773.64","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-44057-6"},{"key":"2026030208250822000_18.3.a041773.65","doi-asserted-by":"publisher","DOI":"10.3390\/ijms26136518"},{"key":"2026030208250822000_18.3.a041773.66","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1000385"},{"key":"2026030208250822000_18.3.a041773.67","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjmcc.2022.03.002"},{"key":"2026030208250822000_18.3.a041773.68","doi-asserted-by":"publisher","DOI":"10.37349\/edd.2024.00057"},{"key":"2026030208250822000_18.3.a041773.69","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-025-09491-0"},{"key":"2026030208250822000_18.3.a041773.70","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00035.2006"},{"key":"2026030208250822000_18.3.a041773.71","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00182.2014"},{"key":"2026030208250822000_18.3.a041773.72","doi-asserted-by":"publisher","DOI":"10.1038\/s42255-025-01250-9"},{"key":"2026030208250822000_18.3.a041773.73","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.69312"},{"key":"2026030208250822000_18.3.a041773.74","doi-asserted-by":"publisher","DOI":"10.1186\/s13024-020-00367-7"},{"key":"2026030208250822000_18.3.a041773.75","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.50973"},{"key":"2026030208250822000_18.3.a041773.76","doi-asserted-by":"publisher","DOI":"10.3390\/antiox12081648"},{"key":"2026030208250822000_18.3.a041773.77","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201801042"},{"key":"2026030208250822000_18.3.a041773.78","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2021.626117"},{"key":"2026030208250822000_18.3.a041773.79","doi-asserted-by":"publisher","DOI":"10.1038\/s41580-018-0052-8"},{"key":"2026030208250822000_18.3.a041773.80","doi-asserted-by":"publisher","DOI":"10.1021\/bi2018909"},{"key":"2026030208250822000_18.3.a041773.81","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2016.12.038"},{"key":"2026030208250822000_18.3.a041773.82","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2019.04.069"},{"key":"2026030208250822000_18.3.a041773.83","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2015.08.010"},{"key":"2026030208250822000_18.3.a041773.84","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0092124"},{"key":"2026030208250822000_18.3.a041773.85","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2021.752260"},{"key":"2026030208250822000_18.3.a041773.86","doi-asserted-by":"publisher","DOI":"10.1093\/PROCEL\/PWAC026"},{"key":"2026030208250822000_18.3.a041773.87","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2024.107409"},{"key":"2026030208250822000_18.3.a041773.88","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M115.670166"},{"key":"2026030208250822000_18.3.a041773.89","doi-asserted-by":"publisher","DOI":"10.1016\/S0143416002001872"},{"key":"2026030208250822000_18.3.a041773.90","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200802164"},{"key":"2026030208250822000_18.3.a041773.91","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2016.11.020"},{"key":"2026030208250822000_18.3.a041773.92","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddm154"},{"key":"2026030208250822000_18.3.a041773.93","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M113.495119"},{"key":"2026030208250822000_18.3.a041773.94","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.E16-03-0193"},{"key":"2026030208250822000_18.3.a041773.95","doi-asserted-by":"publisher","DOI":"10.1055\/s-0033-1358522"},{"key":"2026030208250822000_18.3.a041773.96","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/21.5.983"},{"key":"2026030208250822000_18.3.a041773.97","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2019.04.010"},{"key":"2026030208250822000_18.3.a041773.98","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2551-y"},{"key":"2026030208250822000_18.3.a041773.99","doi-asserted-by":"publisher","DOI":"10.1126\/science.aan6009"},{"key":"2026030208250822000_18.3.a041773.100","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2002.33613"},{"key":"2026030208250822000_18.3.a041773.101","doi-asserted-by":"publisher","DOI":"10.1111\/j.1530-0277.2011.01602.x"},{"key":"2026030208250822000_18.3.a041773.102","doi-asserted-by":"publisher","DOI":"10.1038\/s42255-024-00985-1"},{"key":"2026030208250822000_18.3.a041773.103","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2016.1166318"},{"key":"2026030208250822000_18.3.a041773.104","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-024-07217-0"},{"key":"2026030208250822000_18.3.a041773.105","doi-asserted-by":"publisher","DOI":"10.37349\/edd.2024.00062"},{"key":"2026030208250822000_18.3.a041773.106","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110.167155"},{"key":"2026030208250822000_18.3.a041773.107","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.11553"},{"key":"2026030208250822000_18.3.a041773.108","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/7086807"},{"key":"2026030208250822000_18.3.a041773.109","doi-asserted-by":"publisher","DOI":"10.3389\/fmolb.2020.00064"},{"key":"2026030208250822000_18.3.a041773.110","doi-asserted-by":"publisher","DOI":"10.1126\/science.1175145"},{"key":"2026030208250822000_18.3.a041773.111","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1308558110"},{"key":"2026030208250822000_18.3.a041773.112","doi-asserted-by":"publisher","DOI":"10.1186\/s13046-019-1135-x"},{"key":"2026030208250822000_18.3.a041773.113","doi-asserted-by":"publisher","DOI":"10.1002\/1873-3468.14078"},{"key":"2026030208250822000_18.3.a041773.114","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23158348"},{"key":"2026030208250822000_18.3.a041773.115","doi-asserted-by":"publisher","DOI":"10.1007\/s10545-011-9382-9"},{"key":"2026030208250822000_18.3.a041773.116","doi-asserted-by":"publisher","DOI":"10.15252\/embr.201643748"},{"key":"2026030208250822000_18.3.a041773.117","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1807811115"},{"key":"2026030208250822000_18.3.a041773.118","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/6626484"},{"key":"2026030208250822000_18.3.a041773.119","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1003722"},{"key":"2026030208250822000_18.3.a041773.120","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00246.2010"},{"key":"2026030208250822000_18.3.a041773.121","doi-asserted-by":"publisher","DOI":"10.1038\/nature02246"},{"key":"2026030208250822000_18.3.a041773.122","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2015.04.004"},{"key":"2026030208250822000_18.3.a041773.123","doi-asserted-by":"publisher","DOI":"10.1186\/s12964-021-00762-7"},{"key":"2026030208250822000_18.3.a041773.124","first-page":"274","article-title":"Alcohol metabolism's damaging effects on the cell: a focus on reactive oxygen generation by the enzyme cytochrome P450 2E1","volume":"29","year":"2006","journal-title":"Alcohol Res Health"},{"key":"2026030208250822000_18.3.a041773.125","doi-asserted-by":"publisher","DOI":"10.1172\/JCI198334"},{"key":"2026030208250822000_18.3.a041773.126","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.199562"},{"key":"2026030208250822000_18.3.a041773.127","doi-asserted-by":"publisher","DOI":"10.1038\/cdd.2012.128"},{"key":"2026030208250822000_18.3.a041773.128","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-15-1987"},{"key":"2026030208250822000_18.3.a041773.129","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.RA118.004498"},{"key":"2026030208250822000_18.3.a041773.130","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.109.160879"},{"key":"2026030208250822000_18.3.a041773.131","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M309280200"},{"key":"2026030208250822000_18.3.a041773.132","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M116.762567"},{"key":"2026030208250822000_18.3.a041773.133","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-42564-0"},{"key":"2026030208250822000_18.3.a041773.134","doi-asserted-by":"publisher","DOI":"10.1042\/BST20230012"},{"key":"2026030208250822000_18.3.a041773.135","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-023-05061-7"},{"key":"2026030208250822000_18.3.a041773.136","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.13.2.447"},{"key":"2026030208250822000_18.3.a041773.137","doi-asserted-by":"publisher","DOI":"10.3390\/v15122359"},{"key":"2026030208250822000_18.3.a041773.138","doi-asserted-by":"publisher","DOI":"10.1002\/hep.30191"},{"key":"2026030208250822000_18.3.a041773.139","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-12912-0"},{"key":"2026030208250822000_18.3.a041773.140","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines8110451"},{"key":"2026030208250822000_18.3.a041773.141","doi-asserted-by":"publisher","DOI":"10.7150\/ijbs.71571"},{"key":"2026030208250822000_18.3.a041773.142","doi-asserted-by":"publisher","DOI":"10.3390\/biom12121778"},{"key":"2026030208250822000_18.3.a041773.143","doi-asserted-by":"publisher","DOI":"10.1186\/s13578-024-01315-4"},{"key":"2026030208250822000_18.3.a041773.144","doi-asserted-by":"publisher","DOI":"10.1186\/s12944-024-02108-x"},{"key":"2026030208250822000_18.3.a041773.145","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1011700"},{"key":"2026030208250822000_18.3.a041773.146","doi-asserted-by":"publisher","DOI":"10.3390\/ijms26094256"},{"key":"2026030208250822000_18.3.a041773.147","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-78935-w"},{"key":"2026030208250822000_18.3.a041773.148","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.150041"},{"key":"2026030208250822000_18.3.a041773.149","doi-asserted-by":"publisher","DOI":"10.1186\/s12929-023-00975-7"},{"key":"2026030208250822000_18.3.a041773.150","doi-asserted-by":"publisher","DOI":"10.1038\/s41418-024-01414-2"},{"key":"2026030208250822000_18.3.a041773.151","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2025.1614940"},{"key":"2026030208250822000_18.3.a041773.152","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2024.114879"},{"key":"2026030208250822000_18.3.a041773.153","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2007.11.004"},{"key":"2026030208250822000_18.3.a041773.154","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2021.710420"},{"key":"2026030208250822000_18.3.a041773.155","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0183426"},{"key":"2026030208250822000_18.3.a041773.156","doi-asserted-by":"publisher","DOI":"10.3390\/cells9040837"},{"key":"2026030208250822000_18.3.a041773.157","doi-asserted-by":"publisher","DOI":"10.1002\/hep.32604"},{"key":"2026030208250822000_18.3.a041773.158","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.159186"},{"key":"2026030208250822000_18.3.a041773.159","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00437.2010"},{"key":"2026030208250822000_18.3.a041773.160","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M112.433847"},{"key":"2026030208250822000_18.3.a041773.161","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2012.10.011"},{"key":"2026030208250822000_18.3.a041773.162","doi-asserted-by":"publisher","DOI":"10.1002\/biof.5520080309"},{"key":"2026030208250822000_18.3.a041773.163","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.08828"},{"key":"2026030208250822000_18.3.a041773.164","doi-asserted-by":"publisher","DOI":"10.1042\/BJ20080868"},{"key":"2026030208250822000_18.3.a041773.165","doi-asserted-by":"publisher","DOI":"10.1038\/s41418-023-01251-9"},{"key":"2026030208250822000_18.3.a041773.166","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.adu9512"},{"key":"2026030208250822000_18.3.a041773.167","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-13668-3"},{"key":"2026030208250822000_18.3.a041773.168","doi-asserted-by":"publisher","DOI":"10.3390\/antiox11050801"},{"key":"2026030208250822000_18.3.a041773.169","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddp563"},{"key":"2026030208250822000_18.3.a041773.170","doi-asserted-by":"publisher","DOI":"10.1016\/0005-2736(81)90335-7"},{"key":"2026030208250822000_18.3.a041773.171","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a004317"},{"key":"2026030208250822000_18.3.a041773.172","doi-asserted-by":"publisher","DOI":"10.1016\/S0968-0004(97)01143-2"},{"key":"2026030208250822000_18.3.a041773.173","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M506623200"},{"key":"2026030208250822000_18.3.a041773.174","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2011.10.005"},{"key":"2026030208250822000_18.3.a041773.175","doi-asserted-by":"publisher","DOI":"10.1177\/17562848211031394"},{"key":"2026030208250822000_18.3.a041773.176","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201511036"},{"key":"2026030208250822000_18.3.a041773.177","doi-asserted-by":"publisher","DOI":"10.1111\/hepr.13832"},{"key":"2026030208250822000_18.3.a041773.178","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2024.107485"},{"key":"2026030208250822000_18.3.a041773.179","doi-asserted-by":"publisher","DOI":"10.1002\/j.2040-4603.2022.tb00210.x"},{"key":"2026030208250822000_18.3.a041773.180","doi-asserted-by":"publisher","DOI":"10.3390\/cells8060638"},{"key":"2026030208250822000_18.3.a041773.181","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2020.628222"},{"key":"2026030208250822000_18.3.a041773.182","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.16398"},{"key":"2026030208250822000_18.3.a041773.183","doi-asserted-by":"publisher","DOI":"10.1038\/s42003-020-0832-5"},{"key":"2026030208250822000_18.3.a041773.184","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2021.637852"},{"key":"2026030208250822000_18.3.a041773.185","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2020.101674"},{"key":"2026030208250822000_18.3.a041773.186","doi-asserted-by":"publisher","DOI":"10.1002\/hep.26465"},{"key":"2026030208250822000_18.3.a041773.187","doi-asserted-by":"publisher","DOI":"10.1038\/s41423-025-01298-3"},{"key":"2026030208250822000_18.3.a041773.188","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2022.111803"},{"key":"2026030208250822000_18.3.a041773.189","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2018.00192"},{"key":"2026030208250822000_18.3.a041773.190","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201508099"},{"key":"2026030208250822000_18.3.a041773.191","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2017.02.032"},{"key":"2026030208250822000_18.3.a041773.192","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2018.11.008"},{"key":"2026030208250822000_18.3.a041773.193","doi-asserted-by":"publisher","DOI":"10.1111\/acer.14299"},{"key":"2026030208250822000_18.3.a041773.194","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1012044107"},{"key":"2026030208250822000_18.3.a041773.195","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines10061288"},{"key":"2026030208250822000_18.3.a041773.196","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-67696-4_11"},{"key":"2026030208250822000_18.3.a041773.197","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2014.01.013"},{"key":"2026030208250822000_18.3.a041773.198","doi-asserted-by":"publisher","DOI":"10.15252\/embj.2021110476"},{"key":"2026030208250822000_18.3.a041773.199","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2003.50398"},{"key":"2026030208250822000_18.3.a041773.200","doi-asserted-by":"publisher","DOI":"10.1038\/nature09358"},{"key":"2026030208250822000_18.3.a041773.201","doi-asserted-by":"publisher","DOI":"10.1016\/bs.ircmb.2019.11.002"},{"key":"2026030208250822000_18.3.a041773.202","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2022.012"},{"key":"2026030208250822000_18.3.a041773.203","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbabio.2007.07.011"},{"key":"2026030208250822000_18.3.a041773.204","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2014.12.007"},{"key":"2026030208250822000_18.3.a041773.205","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0055785"},{"key":"2026030208250822000_18.3.a041773.206","doi-asserted-by":"publisher","DOI":"10.1093\/pnasnexus\/pgae229"},{"key":"2026030208250822000_18.3.a041773.207","doi-asserted-by":"publisher","DOI":"10.1038\/s41575-024-01014-y"},{"key":"2026030208250822000_18.3.a041773.208","doi-asserted-by":"publisher","DOI":"10.3390\/antiox13080906"},{"key":"2026030208250822000_18.3.a041773.209","doi-asserted-by":"publisher","DOI":"10.1038\/emboj.2013.157"},{"key":"2026030208250822000_18.3.a041773.210","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.70033"},{"key":"2026030208250822000_18.3.a041773.211","doi-asserted-by":"publisher","DOI":"10.4161\/cc.10.23.18384"},{"key":"2026030208250822000_18.3.a041773.212","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200205091"},{"key":"2026030208250822000_18.3.a041773.213","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.2008.49"},{"key":"2026030208250822000_18.3.a041773.214","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2017.167"},{"key":"2026030208250822000_18.3.a041773.215","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2017.6990"},{"key":"2026030208250822000_18.3.a041773.216","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201311014"},{"key":"2026030208250822000_18.3.a041773.217","doi-asserted-by":"publisher","DOI":"10.1126\/science.280.5370.1763"},{"key":"2026030208250822000_18.3.a041773.218","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24054394"},{"key":"2026030208250822000_18.3.a041773.219","doi-asserted-by":"publisher","DOI":"10.3892\/ijo.2019.4696"},{"key":"2026030208250822000_18.3.a041773.220","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2025.1584932"},{"key":"2026030208250822000_18.3.a041773.221","doi-asserted-by":"publisher","DOI":"10.2174\/1566524016666160523143937"},{"key":"2026030208250822000_18.3.a041773.222","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-024-01969-z"},{"key":"2026030208250822000_18.3.a041773.223","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbc.2024.107151"},{"key":"2026030208250822000_18.3.a041773.224","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2024.103256"},{"key":"2026030208250822000_18.3.a041773.225","doi-asserted-by":"publisher","DOI":"10.1038\/srep27351"},{"key":"2026030208250822000_18.3.a041773.226","doi-asserted-by":"publisher","DOI":"10.26508\/lsa.201900527"},{"key":"2026030208250822000_18.3.a041773.227","doi-asserted-by":"publisher","DOI":"10.1126\/science.1242993"},{"key":"2026030208250822000_18.3.a041773.228","doi-asserted-by":"publisher","DOI":"10.1038\/cddis.2013.453"},{"key":"2026030208250822000_18.3.a041773.229","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22020946"},{"key":"2026030208250822000_18.3.a041773.230","doi-asserted-by":"publisher","DOI":"10.1172\/JCI82204"},{"key":"2026030208250822000_18.3.a041773.231","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201903090"},{"key":"2026030208250822000_18.3.a041773.232","doi-asserted-by":"publisher","DOI":"10.1096\/fj.201903051R"},{"key":"2026030208250822000_18.3.a041773.233","doi-asserted-by":"publisher","DOI":"10.4161\/oxim.3.3.12288"},{"key":"2026030208250822000_18.3.a041773.234","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.72.3.714"},{"key":"2026030208250822000_18.3.a041773.235","doi-asserted-by":"publisher","DOI":"10.3390\/ijms241814066"},{"key":"2026030208250822000_18.3.a041773.236","doi-asserted-by":"publisher","DOI":"10.1038\/sj.emboj.7600559"},{"key":"2026030208250822000_18.3.a041773.237","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjmcc.2017.09.009"},{"key":"2026030208250822000_18.3.a041773.238","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmet.2022.101566"},{"key":"2026030208250822000_18.3.a041773.239","doi-asserted-by":"publisher","DOI":"10.1038\/s44161-024-00463-7"},{"key":"2026030208250822000_18.3.a041773.240","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00270.2015"},{"key":"2026030208250822000_18.3.a041773.241","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1012872"},{"key":"2026030208250822000_18.3.a041773.242","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2011.11.004"},{"key":"2026030208250822000_18.3.a041773.243","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200608073"},{"key":"2026030208250822000_18.3.a041773.244","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmet.2024.101982"},{"key":"2026030208250822000_18.3.a041773.245","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-021-05488-2"},{"key":"2026030208250822000_18.3.a041773.246","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.026625"},{"key":"2026030208250822000_18.3.a041773.247","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a004010"},{"key":"2026030208250822000_18.3.a041773.248","doi-asserted-by":"publisher","DOI":"10.1016\/j.mito.2008.07.008"},{"key":"2026030208250822000_18.3.a041773.249","doi-asserted-by":"publisher","DOI":"10.1093\/jmcb\/mjw004"},{"key":"2026030208250822000_18.3.a041773.250","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-37214-4"},{"key":"2026030208250822000_18.3.a041773.251","doi-asserted-by":"publisher","DOI":"10.1097\/HC9.0000000000000534"},{"key":"2026030208250822000_18.3.a041773.252","doi-asserted-by":"publisher","DOI":"10.3390\/toxics13030155"},{"key":"2026030208250822000_18.3.a041773.253","doi-asserted-by":"publisher","DOI":"10.1042\/EBC20170104"},{"key":"2026030208250822000_18.3.a041773.254","doi-asserted-by":"publisher","DOI":"10.1085\/jgp.201311096"},{"key":"2026030208250822000_18.3.a041773.255","doi-asserted-by":"publisher","DOI":"10.2337\/db13-1751"},{"key":"2026030208250822000_18.3.a041773.256","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2017.09.016"},{"key":"2026030208250822000_18.3.a041773.257","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2010.3779"},{"key":"2026030208250822000_18.3.a041773.258","doi-asserted-by":"publisher","DOI":"10.1007\/s11302-024-10044-9"},{"key":"2026030208250822000_18.3.a041773.259","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-34710-x"},{"key":"2026030208250822000_18.3.a041773.260","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2020.108486"},{"key":"2026030208250822000_18.3.a041773.261","doi-asserted-by":"publisher","DOI":"10.3390\/cells10071737"},{"key":"2026030208250822000_18.3.a041773.262","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M402245200"},{"key":"2026030208250822000_18.3.a041773.263","doi-asserted-by":"publisher","DOI":"10.1038\/cdd.2012.74"},{"key":"2026030208250822000_18.3.a041773.264","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-015-3704-7"},{"key":"2026030208250822000_18.3.a041773.265","doi-asserted-by":"publisher","DOI":"10.1042\/BCJ20160255"},{"key":"2026030208250822000_18.3.a041773.266","doi-asserted-by":"publisher","DOI":"10.1186\/s12944-020-01210-0"},{"key":"2026030208250822000_18.3.a041773.267","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.e20-09-0605"},{"key":"2026030208250822000_18.3.a041773.268","doi-asserted-by":"publisher","DOI":"10.17305\/bb.2023.9698"},{"key":"2026030208250822000_18.3.a041773.269","doi-asserted-by":"publisher","DOI":"10.1186\/s12967-025-06384-8"},{"key":"2026030208250822000_18.3.a041773.270","doi-asserted-by":"publisher","DOI":"10.1111\/bph.17432"},{"key":"2026030208250822000_18.3.a041773.271","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.21.22.7721-7730.2001"},{"key":"2026030208250822000_18.3.a041773.272","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2023.133142"},{"key":"2026030208250822000_18.3.a041773.273","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00108.2010"},{"key":"2026030208250822000_18.3.a041773.274","doi-asserted-by":"publisher","DOI":"10.3390\/ijms19082291"},{"key":"2026030208250822000_18.3.a041773.275","doi-asserted-by":"publisher","DOI":"10.1038\/s12276-022-00923-9"},{"key":"2026030208250822000_18.3.a041773.276","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2024.09.046"},{"key":"2026030208250822000_18.3.a041773.277","doi-asserted-by":"publisher","DOI":"10.1007\/s00011-020-01351-z"},{"key":"2026030208250822000_18.3.a041773.278","doi-asserted-by":"publisher","DOI":"10.1186\/s13395-021-00280-7"},{"key":"2026030208250822000_18.3.a041773.279","doi-asserted-by":"publisher","DOI":"10.1186\/s12882-018-0940-3"},{"key":"2026030208250822000_18.3.a041773.280","doi-asserted-by":"publisher","DOI":"10.1002\/hep.30060"},{"key":"2026030208250822000_18.3.a041773.281","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2022.103996"},{"key":"2026030208250822000_18.3.a041773.282","doi-asserted-by":"publisher","DOI":"10.15252\/embr.201541486"},{"key":"2026030208250822000_18.3.a041773.283","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v13.i16.2352"},{"key":"2026030208250822000_18.3.a041773.284","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200406038"},{"key":"2026030208250822000_18.3.a041773.285","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6601838"},{"key":"2026030208250822000_18.3.a041773.286","doi-asserted-by":"publisher","DOI":"10.2337\/db23-1599-P"},{"key":"2026030208250822000_18.3.a041773.287","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-019-2175-z"},{"key":"2026030208250822000_18.3.a041773.288","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2018.10.037"},{"key":"2026030208250822000_18.3.a041773.289","doi-asserted-by":"publisher","DOI":"10.1038\/nrm3028"},{"key":"2026030208250822000_18.3.a041773.290","doi-asserted-by":"publisher","DOI":"10.1126\/science.1219855"},{"key":"2026030208250822000_18.3.a041773.291","doi-asserted-by":"publisher","DOI":"10.1042\/bj1860119"},{"key":"2026030208250822000_18.3.a041773.292","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbabio.2011.09.011"},{"key":"2026030208250822000_18.3.a041773.293","doi-asserted-by":"publisher","DOI":"10.1096\/fj.201601096RRR"},{"key":"2026030208250822000_18.3.a041773.294","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2020.607906"},{"key":"2026030208250822000_18.3.a041773.295","doi-asserted-by":"publisher","DOI":"10.1038\/s41416-019-0658-4"},{"key":"2026030208250822000_18.3.a041773.296","doi-asserted-by":"publisher","DOI":"10.26508\/lsa.202201478"},{"key":"2026030208250822000_18.3.a041773.297","doi-asserted-by":"publisher","DOI":"10.1111\/bph.15767"},{"key":"2026030208250822000_18.3.a041773.298","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2025.16367"},{"key":"2026030208250822000_18.3.a041773.299","doi-asserted-by":"publisher","DOI":"10.2337\/db21-0173"},{"key":"2026030208250822000_18.3.a041773.300","doi-asserted-by":"publisher","DOI":"10.3164\/jcbn.22-73"},{"key":"2026030208250822000_18.3.a041773.301","doi-asserted-by":"publisher","DOI":"10.1111\/acer.13877"},{"key":"2026030208250822000_18.3.a041773.302","doi-asserted-by":"publisher","DOI":"10.1172\/JCI120849"},{"key":"2026030208250822000_18.3.a041773.303","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-019-0094-1"},{"key":"2026030208250822000_18.3.a041773.304","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2019.101120"},{"key":"2026030208250822000_18.3.a041773.305","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2020.606790"},{"key":"2026030208250822000_18.3.a041773.306","doi-asserted-by":"publisher","DOI":"10.1093\/nsr\/nwae039"},{"key":"2026030208250822000_18.3.a041773.307","doi-asserted-by":"publisher","DOI":"10.1093\/gastro\/goae066"},{"key":"2026030208250822000_18.3.a041773.308","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-20993-z"},{"key":"2026030208250822000_18.3.a041773.309","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2021.708695"},{"key":"2026030208250822000_18.3.a041773.310","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00026.2013"}],"container-title":["Cold Spring Harbor Perspectives in Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1101\/cshperspect.a041773","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T16:25:26Z","timestamp":1772468726000},"score":1,"resource":{"primary":{"URL":"http:\/\/cshperspectives.cshlp.org\/lookup\/doi\/10.1101\/cshperspect.a041773"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,19]]},"references-count":310,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2026,3,2]]},"published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.1101\/cshperspect.a041773"],"URL":"https:\/\/doi.org\/10.1101\/cshperspect.a041773","relation":{},"ISSN":["1943-0264"],"issn-type":[{"value":"1943-0264","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,19]]}}}