{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T18:21:26Z","timestamp":1792002086071,"version":"4.4.0"},"reference-count":226,"publisher":"Cold Spring Harbor Laboratory","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cold Spring Harb Perspect Med"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1101\/cshperspect.a041891","type":"journal-article","created":{"date-parts":[[2025,7,28]],"date-time":"2025-07-28T18:00:15Z","timestamp":1753725615000},"page":"a041891","source":"Crossref","is-referenced-by-count":7,"title":["The Mitochondrial Connection in Parkinson's Disease"],"prefix":"10.1101","volume":"16","author":[{"given":"Eric","family":"Schon","sequence":"first","affiliation":[{"name":"Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA"},{"name":"Department of Genetics and Development, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana","family":"Matheoud","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Neurosciences, Universit\u00e9 de Montr\u00e9al, CRCHUM, Montr\u00e9al, Qu\u00e9bec H2X 0A9, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7283-3883","authenticated-orcid":false,"given":"Serge","family":"Przedborski","sequence":"additional","affiliation":[{"name":"Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA"},{"name":"Department of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA"},{"name":"Department of Neuroscience, Columbia University, New York, New York 10032, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"246","published-online":{"date-parts":[[2025,7,28]]},"reference":[{"key":"2026010509251506000_16.1.a041891.1","doi-asserted-by":"publisher","DOI":"10.1038\/290457a0"},{"key":"2026010509251506000_16.1.a041891.2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0703219104"},{"key":"2026010509251506000_16.1.a041891.3","doi-asserted-by":"publisher","DOI":"10.1038\/nrn1767"},{"key":"2026010509251506000_16.1.a041891.4","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2010.091050"},{"key":"2026010509251506000_16.1.a041891.5","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a041646"},{"key":"2026010509251506000_16.1.a041891.6","doi-asserted-by":"publisher","DOI":"10.1016\/0921-8734(92)90020-P"},{"key":"2026010509251506000_16.1.a041891.7","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2005.07.005"},{"key":"2026010509251506000_16.1.a041891.8","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21051772"},{"key":"2026010509251506000_16.1.a041891.9","doi-asserted-by":"publisher","DOI":"10.1038\/sj.emboj.7601253"},{"key":"2026010509251506000_16.1.a041891.10","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1290.042"},{"key":"2026010509251506000_16.1.a041891.11","doi-asserted-by":"publisher","DOI":"10.1038\/ng1769"},{"key":"2026010509251506000_16.1.a041891.12","doi-asserted-by":"publisher","DOI":"10.1038\/81834"},{"key":"2026010509251506000_16.1.a041891.13","doi-asserted-by":"publisher","DOI":"10.1126\/science.1077209"},{"key":"2026010509251506000_16.1.a041891.14","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2021.07.006"},{"key":"2026010509251506000_16.1.a041891.15","doi-asserted-by":"publisher","DOI":"10.1038\/nrn3068"},{"key":"2026010509251506000_16.1.a041891.16","doi-asserted-by":"publisher","DOI":"10.3389\/fnana.2014.00152"},{"key":"2026010509251506000_16.1.a041891.17","doi-asserted-by":"publisher","DOI":"10.1172\/JCI36470"},{"key":"2026010509251506000_16.1.a041891.18","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M510303200"},{"key":"2026010509251506000_16.1.a041891.19","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2016.05.035"},{"key":"2026010509251506000_16.1.a041891.20","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbabio.2018.05.019"},{"key":"2026010509251506000_16.1.a041891.21","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M111.302794"},{"key":"2026010509251506000_16.1.a041891.22","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms4633"},{"key":"2026010509251506000_16.1.a041891.23","doi-asserted-by":"publisher","DOI":"10.15252\/embr.202153086"},{"key":"2026010509251506000_16.1.a041891.24","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.1991.tb02134.x"},{"key":"2026010509251506000_16.1.a041891.25","doi-asserted-by":"publisher","DOI":"10.1038\/nature05865"},{"key":"2026010509251506000_16.1.a041891.26","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddp326"},{"key":"2026010509251506000_16.1.a041891.27","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2007.06.026"},{"key":"2026010509251506000_16.1.a041891.28","doi-asserted-by":"publisher","DOI":"10.1002\/ana.21995"},{"key":"2026010509251506000_16.1.a041891.29","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2009.05.023"},{"key":"2026010509251506000_16.1.a041891.30","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmet.2021.101405"},{"key":"2026010509251506000_16.1.a041891.31","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-444-64074-1.00043-4"},{"key":"2026010509251506000_16.1.a041891.32","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.23-10-04081.2003"},{"key":"2026010509251506000_16.1.a041891.33","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200604016"},{"key":"2026010509251506000_16.1.a041891.34","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M109.066662"},{"key":"2026010509251506000_16.1.a041891.35","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/122.8.1437"},{"key":"2026010509251506000_16.1.a041891.36","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2617-07.2007"},{"key":"2026010509251506000_16.1.a041891.37","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddg044"},{"key":"2026010509251506000_16.1.a041891.38","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(03)00568-3"},{"key":"2026010509251506000_16.1.a041891.39","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-4159.1996.66041617.x"},{"key":"2026010509251506000_16.1.a041891.40","doi-asserted-by":"publisher","DOI":"10.1002\/ana.20831"},{"key":"2026010509251506000_16.1.a041891.41","doi-asserted-by":"publisher","DOI":"10.1038\/nature07534"},{"key":"2026010509251506000_16.1.a041891.42","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1920-10.2010"},{"key":"2026010509251506000_16.1.a041891.43","doi-asserted-by":"publisher","DOI":"10.1038\/79936"},{"key":"2026010509251506000_16.1.a041891.44","doi-asserted-by":"publisher","DOI":"10.3390\/cells8080795"},{"key":"2026010509251506000_16.1.a041891.45","doi-asserted-by":"publisher","DOI":"10.1038\/nature10230"},{"key":"2026010509251506000_16.1.a041891.46","doi-asserted-by":"publisher","DOI":"10.1038\/nrm2275"},{"key":"2026010509251506000_16.1.a041891.47","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddr559"},{"key":"2026010509251506000_16.1.a041891.48","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra022567"},{"key":"2026010509251506000_16.1.a041891.49","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(86)91211-8"},{"key":"2026010509251506000_16.1.a041891.50","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.1999.tb00721.x"},{"key":"2026010509251506000_16.1.a041891.51","doi-asserted-by":"publisher","DOI":"10.1007\/s10863-019-09798-4"},{"key":"2026010509251506000_16.1.a041891.52","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbabio.2015.12.013"},{"key":"2026010509251506000_16.1.a041891.53","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0605208103"},{"key":"2026010509251506000_16.1.a041891.54","doi-asserted-by":"publisher","DOI":"10.1016\/S1534-5807(01)00055-7"},{"key":"2026010509251506000_16.1.a041891.55","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(86)81192-9"},{"key":"2026010509251506000_16.1.a041891.56","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2006.06.025"},{"key":"2026010509251506000_16.1.a041891.57","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-025-03359-w"},{"key":"2026010509251506000_16.1.a041891.58","doi-asserted-by":"publisher","DOI":"10.1038\/nrn2665"},{"key":"2026010509251506000_16.1.a041891.59","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2009.02.013"},{"key":"2026010509251506000_16.1.a041891.60","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddw148"},{"key":"2026010509251506000_16.1.a041891.61","doi-asserted-by":"publisher","DOI":"10.1038\/ncb2012"},{"key":"2026010509251506000_16.1.a041891.62","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2016.1277309"},{"key":"2026010509251506000_16.1.a041891.63","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1992.tb24523.x"},{"key":"2026010509251506000_16.1.a041891.64","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1009921"},{"key":"2026010509251506000_16.1.a041891.65","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2010.3386"},{"key":"2026010509251506000_16.1.a041891.66","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2008.03.009"},{"key":"2026010509251506000_16.1.a041891.67","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-017-0079-3"},{"key":"2026010509251506000_16.1.a041891.68","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a011403"},{"key":"2026010509251506000_16.1.a041891.69","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-014-1345-4"},{"key":"2026010509251506000_16.1.a041891.70","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410440207"},{"key":"2026010509251506000_16.1.a041891.71","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2507-13.2014"},{"key":"2026010509251506000_16.1.a041891.72","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2008.01.007"},{"key":"2026010509251506000_16.1.a041891.73","doi-asserted-by":"publisher","DOI":"10.1038\/nature09536"},{"key":"2026010509251506000_16.1.a041891.74","doi-asserted-by":"publisher","DOI":"10.1038\/nature08221"},{"key":"2026010509251506000_16.1.a041891.75","doi-asserted-by":"publisher","DOI":"10.15252\/embj.201798694"},{"key":"2026010509251506000_16.1.a041891.76","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2022.950767"},{"key":"2026010509251506000_16.1.a041891.77","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcb.2008.12.002"},{"key":"2026010509251506000_16.1.a041891.78","doi-asserted-by":"publisher","DOI":"10.1002\/mds.28075"},{"key":"2026010509251506000_16.1.a041891.79","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2009.07.013"},{"key":"2026010509251506000_16.1.a041891.80","doi-asserted-by":"publisher","DOI":"10.2741\/A118"},{"key":"2026010509251506000_16.1.a041891.81","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1110133108"},{"key":"2026010509251506000_16.1.a041891.82","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2022.05.021"},{"key":"2026010509251506000_16.1.a041891.83","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddm080"},{"key":"2026010509251506000_16.1.a041891.84","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2020.00498"},{"key":"2026010509251506000_16.1.a041891.85","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddq288"},{"key":"2026010509251506000_16.1.a041891.86","first-page":"435","article-title":"Lipid droplets and the management of cellular stress","volume":"92","year":"2019","journal-title":"Yale J Biol Med"},{"key":"2026010509251506000_16.1.a041891.87","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1616332114"},{"key":"2026010509251506000_16.1.a041891.88","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1665-04.2004"},{"key":"2026010509251506000_16.1.a041891.89","doi-asserted-by":"publisher","DOI":"10.1038\/emboj.2010.223"},{"key":"2026010509251506000_16.1.a041891.90","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0984-06.2006"},{"key":"2026010509251506000_16.1.a041891.91","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1972.33"},{"key":"2026010509251506000_16.1.a041891.92","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2008.05383.x"},{"key":"2026010509251506000_16.1.a041891.93","doi-asserted-by":"publisher","DOI":"10.1016\/j.abb.2007.03.034"},{"key":"2026010509251506000_16.1.a041891.94","doi-asserted-by":"publisher","DOI":"10.1038\/s41588-023-01584-8"},{"key":"2026010509251506000_16.1.a041891.95","doi-asserted-by":"publisher","DOI":"10.1186\/s13024-025-00814-3"},{"key":"2026010509251506000_16.1.a041891.96","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0711-11.2011"},{"key":"2026010509251506000_16.1.a041891.97","doi-asserted-by":"publisher","DOI":"10.1038\/nrn2417"},{"key":"2026010509251506000_16.1.a041891.98","doi-asserted-by":"publisher","DOI":"10.1016\/j.mito.2020.10.003"},{"key":"2026010509251506000_16.1.a041891.99","doi-asserted-by":"publisher","DOI":"10.1038\/ng1778"},{"key":"2026010509251506000_16.1.a041891.100","doi-asserted-by":"publisher","DOI":"10.1126\/science.1112125"},{"key":"2026010509251506000_16.1.a041891.101","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2022.112656"},{"key":"2026010509251506000_16.1.a041891.102","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-018-1248-8"},{"key":"2026010509251506000_16.1.a041891.103","doi-asserted-by":"publisher","DOI":"10.1126\/science.6823561"},{"key":"2026010509251506000_16.1.a041891.104","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-51578-1"},{"key":"2026010509251506000_16.1.a041891.105","doi-asserted-by":"publisher","DOI":"10.1186\/s40035-024-00430-z"},{"key":"2026010509251506000_16.1.a041891.106","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1421419112"},{"key":"2026010509251506000_16.1.a041891.107","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2022.09.010"},{"key":"2026010509251506000_16.1.a041891.108","doi-asserted-by":"publisher","DOI":"10.3389\/fmolb.2022.851966"},{"key":"2026010509251506000_16.1.a041891.109","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2004.02567.x"},{"key":"2026010509251506000_16.1.a041891.110","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2006.08.015"},{"key":"2026010509251506000_16.1.a041891.111","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-15626-w"},{"key":"2026010509251506000_16.1.a041891.112","doi-asserted-by":"publisher","DOI":"10.1016\/j.molimm.2018.09.010"},{"key":"2026010509251506000_16.1.a041891.113","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1906565116"},{"key":"2026010509251506000_16.1.a041891.114","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)16983-3"},{"key":"2026010509251506000_16.1.a041891.115","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M109.035774"},{"key":"2026010509251506000_16.1.a041891.116","doi-asserted-by":"publisher","DOI":"10.3390\/cells10092273"},{"key":"2026010509251506000_16.1.a041891.117","doi-asserted-by":"publisher","DOI":"10.1007\/978-981-10-4567-7_4"},{"key":"2026010509251506000_16.1.a041891.118","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0001433"},{"key":"2026010509251506000_16.1.a041891.119","doi-asserted-by":"publisher","DOI":"10.1038\/32096"},{"key":"2026010509251506000_16.1.a041891.120","doi-asserted-by":"publisher","DOI":"10.1172\/JCI32806"},{"key":"2026010509251506000_16.1.a041891.121","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2016.05.039"},{"key":"2026010509251506000_16.1.a041891.122","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.38.8.1285"},{"key":"2026010509251506000_16.1.a041891.123","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.32866"},{"key":"2026010509251506000_16.1.a041891.124","doi-asserted-by":"publisher","DOI":"10.1038\/sj.cdd.4402087"},{"key":"2026010509251506000_16.1.a041891.125","doi-asserted-by":"publisher","DOI":"10.1038\/46311"},{"key":"2026010509251506000_16.1.a041891.126","doi-asserted-by":"publisher","DOI":"10.1007\/978-981-10-4567-7_14"},{"key":"2026010509251506000_16.1.a041891.127","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-017-0027-2"},{"key":"2026010509251506000_16.1.a041891.128","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.191107398"},{"key":"2026010509251506000_16.1.a041891.129","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000006439"},{"key":"2026010509251506000_16.1.a041891.130","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbc.2021.101164"},{"key":"2026010509251506000_16.1.a041891.131","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0611231104"},{"key":"2026010509251506000_16.1.a041891.132","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110.213538"},{"key":"2026010509251506000_16.1.a041891.133","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(19)30320-5"},{"key":"2026010509251506000_16.1.a041891.134","doi-asserted-by":"publisher","DOI":"10.1126\/science.adh9351"},{"key":"2026010509251506000_16.1.a041891.135","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.1000298"},{"key":"2026010509251506000_16.1.a041891.136","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2007.12.038"},{"key":"2026010509251506000_16.1.a041891.137","doi-asserted-by":"publisher","DOI":"10.1038\/s12276-023-01046-5"},{"key":"2026010509251506000_16.1.a041891.138","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.10.5789"},{"key":"2026010509251506000_16.1.a041891.139","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2020.154396"},{"key":"2026010509251506000_16.1.a041891.140","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2006.11.003"},{"key":"2026010509251506000_16.1.a041891.141","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddt068"},{"key":"2026010509251506000_16.1.a041891.142","doi-asserted-by":"publisher","DOI":"10.1002\/stem.1732"},{"key":"2026010509251506000_16.1.a041891.143","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-008-7589-1"},{"key":"2026010509251506000_16.1.a041891.144","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1301170"},{"key":"2026010509251506000_16.1.a041891.145","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410260606"},{"key":"2026010509251506000_16.1.a041891.146","doi-asserted-by":"publisher","DOI":"10.7326\/M19-2534"},{"key":"2026010509251506000_16.1.a041891.147","doi-asserted-by":"publisher","DOI":"10.3389\/fnana.2024.1419108"},{"key":"2026010509251506000_16.1.a041891.148","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a009332"},{"key":"2026010509251506000_16.1.a041891.149","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0508215102"},{"key":"2026010509251506000_16.1.a041891.150","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0609874104"},{"key":"2026010509251506000_16.1.a041891.151","doi-asserted-by":"publisher","DOI":"10.1002\/ana.22034"},{"key":"2026010509251506000_16.1.a041891.152","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2011.4074"},{"key":"2026010509251506000_16.1.a041891.153","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M505143200"},{"key":"2026010509251506000_16.1.a041891.154","doi-asserted-by":"publisher","DOI":"10.1126\/science.1135380"},{"key":"2026010509251506000_16.1.a041891.155","doi-asserted-by":"publisher","DOI":"10.1038\/s41580-019-0180-9"},{"key":"2026010509251506000_16.1.a041891.156","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110.186841"},{"key":"2026010509251506000_16.1.a041891.157","doi-asserted-by":"publisher","DOI":"10.1038\/nrn.2017.25"},{"key":"2026010509251506000_16.1.a041891.158","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(87)90531-5"},{"key":"2026010509251506000_16.1.a041891.159","doi-asserted-by":"publisher","DOI":"10.1001\/archneurol.2009.89"},{"key":"2026010509251506000_16.1.a041891.160","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-016-0140-8"},{"key":"2026010509251506000_16.1.a041891.161","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-09397-2"},{"key":"2026010509251506000_16.1.a041891.162","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)47012-3"},{"key":"2026010509251506000_16.1.a041891.163","doi-asserted-by":"publisher","DOI":"10.1016\/0022-5193(67)90079-3"},{"key":"2026010509251506000_16.1.a041891.164","doi-asserted-by":"publisher","DOI":"10.1038\/s41531-017-0032-2"},{"key":"2026010509251506000_16.1.a041891.165","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.1990.tb02325.x"},{"key":"2026010509251506000_16.1.a041891.166","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2011.06.003"},{"key":"2026010509251506000_16.1.a041891.167","doi-asserted-by":"publisher","DOI":"10.1126\/science.1106653"},{"key":"2026010509251506000_16.1.a041891.168","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/kfi334"},{"key":"2026010509251506000_16.1.a041891.169","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuro.2008.12.015"},{"key":"2026010509251506000_16.1.a041891.170","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2017.00428"},{"key":"2026010509251506000_16.1.a041891.171","doi-asserted-by":"publisher","DOI":"10.1016\/S1534-5807(01)00116-2"},{"key":"2026010509251506000_16.1.a041891.172","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.1990.tb01962.x"},{"key":"2026010509251506000_16.1.a041891.173","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-03957-8"},{"key":"2026010509251506000_16.1.a041891.174","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-4159.1997.68031221.x"},{"key":"2026010509251506000_16.1.a041891.175","doi-asserted-by":"publisher","DOI":"10.1177\/1073858402008003004"},{"key":"2026010509251506000_16.1.a041891.176","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2011.02.010"},{"key":"2026010509251506000_16.1.a041891.177","doi-asserted-by":"publisher","DOI":"10.1038\/nrm.2017.110"},{"key":"2026010509251506000_16.1.a041891.178","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-018-0448-9"},{"key":"2026010509251506000_16.1.a041891.179","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2019.04.019"},{"key":"2026010509251506000_16.1.a041891.180","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2017.00095"},{"key":"2026010509251506000_16.1.a041891.181","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-5793(03)00421-6"},{"key":"2026010509251506000_16.1.a041891.182","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X18770331"},{"key":"2026010509251506000_16.1.a041891.183","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms4996"},{"key":"2026010509251506000_16.1.a041891.184","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2006.09.024"},{"key":"2026010509251506000_16.1.a041891.185","doi-asserted-by":"publisher","DOI":"10.1038\/nature22815"},{"key":"2026010509251506000_16.1.a041891.186","doi-asserted-by":"publisher","DOI":"10.1002\/mds.28850"},{"key":"2026010509251506000_16.1.a041891.187","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410400417"},{"key":"2026010509251506000_16.1.a041891.188","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamcr.2006.04.002"},{"key":"2026010509251506000_16.1.a041891.189","doi-asserted-by":"publisher","DOI":"10.1038\/nrm2952"},{"key":"2026010509251506000_16.1.a041891.190","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-022-00684-6"},{"key":"2026010509251506000_16.1.a041891.191","doi-asserted-by":"publisher","DOI":"10.1002\/1531-8249(200011)48:5<730::AID-ANA6>3.0.CO;2-0"},{"key":"2026010509251506000_16.1.a041891.192","doi-asserted-by":"publisher","DOI":"10.1172\/JCI200318797"},{"key":"2026010509251506000_16.1.a041891.193","doi-asserted-by":"publisher","DOI":"10.15252\/embj.2018100875"},{"key":"2026010509251506000_16.1.a041891.194","doi-asserted-by":"publisher","DOI":"10.1038\/nature02517"},{"key":"2026010509251506000_16.1.a041891.195","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2004.02512.x"},{"key":"2026010509251506000_16.1.a041891.196","doi-asserted-by":"publisher","DOI":"10.1007\/s00702-015-1399-z"},{"key":"2026010509251506000_16.1.a041891.197","doi-asserted-by":"publisher","DOI":"10.1002\/acn3.361"},{"key":"2026010509251506000_16.1.a041891.198","doi-asserted-by":"publisher","DOI":"10.1038\/ng1988"},{"key":"2026010509251506000_16.1.a041891.199","doi-asserted-by":"publisher","DOI":"10.1038\/ng.95"},{"key":"2026010509251506000_16.1.a041891.200","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2005.06.018"},{"key":"2026010509251506000_16.1.a041891.201","doi-asserted-by":"publisher","DOI":"10.1038\/nrn1100"},{"key":"2026010509251506000_16.1.a041891.202","doi-asserted-by":"publisher","DOI":"10.1038\/nm1068"},{"key":"2026010509251506000_16.1.a041891.203","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.051633998"},{"key":"2026010509251506000_16.1.a041891.204","doi-asserted-by":"publisher","DOI":"10.4161\/auto.7.1.13933"},{"key":"2026010509251506000_16.1.a041891.205","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.21-24-09519.2001"},{"key":"2026010509251506000_16.1.a041891.206","doi-asserted-by":"publisher","DOI":"10.1016\/s0079-6123(10)83006-7"},{"key":"2026010509251506000_16.1.a041891.207","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0911187107"},{"key":"2026010509251506000_16.1.a041891.208","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2013.01.067"},{"key":"2026010509251506000_16.1.a041891.209","doi-asserted-by":"publisher","DOI":"10.1098\/rsob.210255"},{"key":"2026010509251506000_16.1.a041891.210","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.genet.39.110304.095751"},{"key":"2026010509251506000_16.1.a041891.211","doi-asserted-by":"publisher","DOI":"10.1002\/aja.1000360106"},{"key":"2026010509251506000_16.1.a041891.212","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2004.11.041"},{"key":"2026010509251506000_16.1.a041891.213","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2007.07.010"},{"key":"2026010509251506000_16.1.a041891.214","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2015.02.002"},{"key":"2026010509251506000_16.1.a041891.215","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2022.06.038"},{"key":"2026010509251506000_16.1.a041891.216","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110.208447"},{"key":"2026010509251506000_16.1.a041891.217","doi-asserted-by":"publisher","DOI":"10.1172\/JCI180478"},{"key":"2026010509251506000_16.1.a041891.218","doi-asserted-by":"publisher","DOI":"10.1038\/nature25486"},{"key":"2026010509251506000_16.1.a041891.219","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0937239100"},{"key":"2026010509251506000_16.1.a041891.220","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2004.02728.x"},{"key":"2026010509251506000_16.1.a041891.221","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.18-20-08145.1998"},{"key":"2026010509251506000_16.1.a041891.222","doi-asserted-by":"publisher","DOI":"10.1038\/nrm3028"},{"key":"2026010509251506000_16.1.a041891.223","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3001059"},{"key":"2026010509251506000_16.1.a041891.224","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1427.023"},{"key":"2026010509251506000_16.1.a041891.225","doi-asserted-by":"publisher","DOI":"10.1038\/nature09663"},{"key":"2026010509251506000_16.1.a041891.226","doi-asserted-by":"publisher","DOI":"10.1038\/ng1341"}],"container-title":["Cold Spring Harbor Perspectives in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1101\/cshperspect.a041891","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T17:25:32Z","timestamp":1767633932000},"score":1,"resource":{"primary":{"URL":"http:\/\/perspectivesinmedicine.cshlp.org\/lookup\/doi\/10.1101\/cshperspect.a041891"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,28]]},"references-count":226,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,1,5]]},"published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1101\/cshperspect.a041891"],"URL":"https:\/\/doi.org\/10.1101\/cshperspect.a041891","relation":{},"ISSN":["2157-1422"],"issn-type":[{"value":"2157-1422","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,28]]}}}