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The Gli3-mediated repression was impaired by anti-Ski antibody and in <jats:italic>Ski<\/jats:italic>-deficient fibroblasts, and Shh-induced <jats:italic>Gli1<\/jats:italic> gene transcription mediated by full-length Gli3 was inhibited by Ski. Furthermore, a <jats:italic>Ski<\/jats:italic> mutation enhanced the digit abnormalities caused by the <jats:italic>Gli3<\/jats:italic> gene mutation. Thus, Ski plays an important role in pattern formation.<\/jats:p>","DOI":"10.1101\/gad.1017302","type":"journal-article","created":{"date-parts":[[2002,11,15]],"date-time":"2002-11-15T18:22:33Z","timestamp":1037384553000},"page":"2843-2848","source":"Crossref","is-referenced-by-count":75,"title":["Ski is involved in transcriptional regulation by the repressor and full-length forms of Gli3"],"prefix":"10.1101","volume":"16","author":[{"given":"Ping","family":"Dai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshie","family":"Shinagawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teruaki","family":"Nomura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Harada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunil 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