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More importantly, we demonstrate that reducing dS6K signaling rescues early larval lethality associated with loss of dTsc1\/2 function, arguing that the S6K pathway is a promising target for the treatment of TSC.<\/jats:p>","DOI":"10.1101\/gad.239102","type":"journal-article","created":{"date-parts":[[2002,10,15]],"date-time":"2002-10-15T22:24:17Z","timestamp":1034720657000},"page":"2627-2632","source":"Crossref","is-referenced-by-count":164,"title":["Lethality of <i>Drosophila<\/i> lacking TSC tumor suppressor function rescued by reducing dS6K signaling"],"prefix":"10.1101","volume":"16","author":[{"given":"Thomas","family":"Radimerski","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacques","family":"Montagne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maja","family":"Hemmings-Mieszczak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"246","published-online":{"date-parts":[[2002,10,15]]},"reference":[{"key":"2021111508103713000_16.20.2627.1","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1523\/JNEUROSCI.18-03-00999.1998","article-title":"Single neuron mosaics of the Drosophila gigas mutant project beyond normal targets and modify behavior.","volume":"18","author":"Canal","year":"1998","journal-title":"J. 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