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The resulting genotypes were analyzed using a maximum likelihood approach searching for shared homozygous haplotypes among affected individuals. Three candidate regions for the syndactyly locus emerged from this initial screening. syndactyly was shown to map to one of these candidate regions on chromosome 15 by genotyping 29 additional individuals linking founder and affected offspring and performing a conventional linkage analysis with the LINKAGE programs. This study illustrates the potential of identity-by-descent mapping in livestock populations.<\/jats:p>","DOI":"10.1101\/gr.6.7.580","type":"journal-article","created":{"date-parts":[[2007,6,5]],"date-time":"2007-06-05T21:18:07Z","timestamp":1181078287000},"page":"580-589","source":"Crossref","is-referenced-by-count":31,"title":["Identity-by-descent mapping of recessive traits in livestock: application to map the bovine syndactyly locus to chromosome 15."],"prefix":"10.1101","volume":"6","author":[{"given":"C","family":"Charlier","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"Farnir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Berzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Vanmanshoven","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B","family":"Brouwers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H","family":"Vromans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Georges","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"246","published-online":{"date-parts":[[1996,7,1]]},"reference":[{"key":"2021111810255304000_6.7.580.1","doi-asserted-by":"publisher","DOI":"10.1038\/ng0394-227"},{"key":"2021111810255304000_6.7.580.2","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1093\/genetics\/136.2.619","article-title":"A genetic linkage map for cattle.","volume":"136","year":"1994","journal-title":"Genetics"},{"key":"2021111810255304000_6.7.580.3","first-page":"252","article-title":"Faster sequential genetic linkage computations.","volume":"53","year":"1993","journal-title":"Am. 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