{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T08:58:42Z","timestamp":1775293122161,"version":"3.50.1"},"reference-count":43,"publisher":"Cold Spring Harbor Laboratory","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Genome Res."],"published-print":{"date-parts":[[1997,10,1]]},"DOI":"10.1101\/gr.7.10.959","type":"journal-article","created":{"date-parts":[[2017,5,3]],"date-time":"2017-05-03T00:22:45Z","timestamp":1493770965000},"page":"959-966","source":"Crossref","is-referenced-by-count":218,"title":["Long Human\u2013Mouse Sequence Alignments Reveal Novel Regulatory Elements: A Reason to Sequence the Mouse\u2009Genome"],"prefix":"10.1101","volume":"7","author":[{"given":"Ross C.","family":"Hardison","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Oeltjen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Webb","family":"Miller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"246","published-online":{"date-parts":[[1997,10,1]]},"reference":[{"key":"2021111810271647000_7.10.959.1","doi-asserted-by":"publisher","DOI":"10.1126\/science.2047873"},{"key":"2021111810271647000_7.10.959.2","doi-asserted-by":"publisher","DOI":"10.1016\/S0968-0004(00)89051-9"},{"key":"2021111810271647000_7.10.959.3","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-437X(96)80020-7"},{"key":"2021111810271647000_7.10.959.4","doi-asserted-by":"publisher","DOI":"10.1006\/geno.1996.0298"},{"key":"2021111810271647000_7.10.959.5","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.88.5.1626"},{"key":"2021111810271647000_7.10.959.6","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(84)90547-6"},{"key":"2021111810271647000_7.10.959.7","doi-asserted-by":"crossref","first-page":"1718","DOI":"10.1002\/j.1460-2075.1995.tb07161.x","article-title":"Contrasting effects of alpha and beta globin regulatory elements on chromatin structure may be related to their different chromosomal environments.","volume":"14","author":"Craddock","year":"1995","journal-title":"EMBO J."},{"key":"2021111810271647000_7.10.959.8","doi-asserted-by":"crossref","first-page":"2022","DOI":"10.1214\/aop\/1176988493","article-title":"Limit distribution of maximal non-aligned two-sequence segmental score.","volume":"22","author":"Dembo","year":"1994","journal-title":"Ann. Probabil."},{"key":"2021111810271647000_7.10.959.9","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.272.1.369"},{"key":"2021111810271647000_7.10.959.10","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/15.22.9215"},{"key":"2021111810271647000_7.10.959.11","doi-asserted-by":"publisher","DOI":"10.1038\/ng0397-252"},{"key":"2021111810271647000_7.10.959.12","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.83.5.1359"},{"key":"2021111810271647000_7.10.959.13","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.1993.0015"},{"key":"2021111810271647000_7.10.959.14","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.80.24.7551"},{"key":"2021111810271647000_7.10.959.15","doi-asserted-by":"publisher","DOI":"10.1006\/mpev.1996.0004"},{"key":"2021111810271647000_7.10.959.16","doi-asserted-by":"publisher","DOI":"10.1016\/0022-2836(91)90209-O"},{"key":"2021111810271647000_7.10.959.17","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1182\/blood.V87.3.1036.bloodjournal8731036","article-title":"Analysis of Bruton\u2019s tyrosine kinase gene promoter reveals critical PU.1 and SP1 sites.","volume":"87","author":"Himmelman","year":"1996","journal-title":"Blood"},{"key":"2021111810271647000_7.10.959.18","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/6.4.373"},{"key":"2021111810271647000_7.10.959.19","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/24.21.4327"},{"key":"2021111810271647000_7.10.959.20","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.271.20.11871"},{"key":"2021111810271647000_7.10.959.21","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.270.8.3965"},{"key":"2021111810271647000_7.10.959.22","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-9525(00)89108-8"},{"key":"2021111810271647000_7.10.959.23","doi-asserted-by":"publisher","DOI":"10.1038\/ng0594-48"},{"key":"2021111810271647000_7.10.959.24","doi-asserted-by":"publisher","DOI":"10.1006\/geno.1994.1097"},{"key":"2021111810271647000_7.10.959.25","doi-asserted-by":"crossref","first-page":"32421","DOI":"10.1074\/jbc.271.50.32421","article-title":"A novel DNA binding protein, HS2NF5, interacts with a functionally important sequence of the human \u03b2-globin locus control region.","volume":"13","author":"Lam","year":"1996","journal-title":"J. Biol. Chem."},{"key":"2021111810271647000_7.10.959.26","doi-asserted-by":"publisher","DOI":"10.1016\/0888-7543(95)80056-R"},{"key":"2021111810271647000_7.10.959.27","doi-asserted-by":"publisher","DOI":"10.1006\/geno.1996.0303"},{"key":"2021111810271647000_7.10.959.28","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.87.17.6703"},{"key":"2021111810271647000_7.10.959.29","doi-asserted-by":"crossref","first-page":"8456","DOI":"10.1101\/gr.6.9.846","article-title":"Comparative analysis of 1196 orthologous mouse and human full-length mRNA and protein sequences.","volume":"6","author":"Makalowski","year":"1996","journal-title":"Genome Res."},{"key":"2021111810271647000_7.10.959.30","doi-asserted-by":"publisher","DOI":"10.1016\/0022-2836(89)90362-8"},{"key":"2021111810271647000_7.10.959.31","doi-asserted-by":"publisher","DOI":"10.1126\/science.2667136"},{"key":"2021111810271647000_7.10.959.32","first-page":"1955","article-title":"Cell specific expression of human Bruton\u2019s agammaglobulinemia tyrosine kinase gene (Btk) is regulated by Sp1- and Spi-1\/PU.1-family members.","volume":"13","author":"Muller","year":"1996","journal-title":"Oncogene"},{"key":"2021111810271647000_7.10.959.33","doi-asserted-by":"publisher","DOI":"10.1101\/gr.7.4.315"},{"key":"2021111810271647000_7.10.959.34","doi-asserted-by":"crossref","first-page":"E2","DOI":"10.1016\/S0008-6363(95)00081-X","article-title":"Regulation of cardiac gene expression during development.","volume":"31","author":"Robbins","year":"1996","journal-title":"Cardiovascul. Res."},{"key":"2021111810271647000_7.10.959.35","doi-asserted-by":"publisher","DOI":"10.1126\/science.274.5287.540"},{"key":"2021111810271647000_7.10.959.36","doi-asserted-by":"crossref","unstructured":"Shewchuk, B.M. 1997. \u201cEffect of CpG islands from the \u03b1-globin gene cluster on gene expression: Evidence for a chromatin-dependent activity.\u201d Ph.D. Thesis. The Pennsylvania State University, University Park, PA..","DOI":"10.1128\/MCB.17.10.5856"},{"key":"2021111810271647000_7.10.959.37","doi-asserted-by":"crossref","first-page":"5856","DOI":"10.1128\/MCB.17.10.5856","article-title":"CpG islands from the \u03b1-globin gene cluster increase gene expression in an integration-dependent manner.","volume":"17","author":"Shewchuk","year":"1997","journal-title":"Mol. Cell. Biol."},{"key":"2021111810271647000_7.10.959.38","doi-asserted-by":"crossref","first-page":"5607","DOI":"10.4049\/jimmunol.153.12.5607","article-title":"Genomic organization of mouse and human\u2019s Bruton\u2019s tyrosine agammaglobulinemia tyrosine kinase (Btk) loci.","volume":"153","author":"Sideras","year":"1994","journal-title":"J. Immunol."},{"key":"2021111810271647000_7.10.959.39","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-437X(96)80030-X"},{"key":"2021111810271647000_7.10.959.40","unstructured":"Stamatoyannopoulos G. Nienhuis A.W. (1994) Hemoglobin switching. in The molecular basis of blood diseases, eds Stamatoyannopoulos G. Nienhuis A.W. Majerus P.W. Varmus H. (W.B. Saunders, Philadelphia, PA), pp 107\u2013155."},{"key":"2021111810271647000_7.10.959.41","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.82.19.6384"},{"key":"2021111810271647000_7.10.959.42","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)81845-0"},{"key":"2021111810271647000_7.10.959.43","first-page":"5439","article-title":"Nuclear protein binding sites in a transcriptional control region of the rabbit \u03b1-globin gene.","volume":"13","author":"Yost","year":"1993","journal-title":"Mol. Cell. Biol."}],"container-title":["Genome Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1101\/gr.7.10.959","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T11:22:24Z","timestamp":1692789744000},"score":1,"resource":{"primary":{"URL":"http:\/\/genome.cshlp.org\/lookup\/doi\/10.1101\/gr.7.10.959"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,10,1]]},"references-count":43,"journal-issue":{"issue":"10","published-print":{"date-parts":[[1997,10,1]]}},"alternative-id":["10.1101\/gr.7.10.959"],"URL":"https:\/\/doi.org\/10.1101\/gr.7.10.959","relation":{},"ISSN":["1088-9051","1549-5469"],"issn-type":[{"value":"1088-9051","type":"print"},{"value":"1549-5469","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,10,1]]}}}