{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T14:39:44Z","timestamp":1790433584210,"version":"4.1.0"},"reference-count":32,"publisher":"Cold Spring Harbor Laboratory","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Learn. Mem."],"published-print":{"date-parts":[[2000,11,1]]},"abstract":"<jats:p>Regular spontaneous oscillations were recorded both electro- and optophysiologically using a voltage-sensitive absorption dye in the olfactory part of the brain (procerebral lobe of the cerebral ganglia) of the gastropod mollusk <jats:italic>Helix lucorum.<\/jats:italic> Odor application caused transient changes in procerebral oscillations, and an odor-evoked potential was recorded in the procerebrum (PC). The wave of evoked potential originated near the place of olfactory nerve entrance into the PC and propagated via the procerebral neuropile toward the cell body layer. The spread of the odor-evoked potential corresponded roughly to the neuropile area, whereas the spontaneous oscillations were recorded in the cell body layer of the PC and were not observed in the neuropile. Evoked potential did not produce additional events intercalated into the ongoing spontaneous oscillations. Changes in parameters of spontaneous oscillations to the repeated presentations of the same odor were variable. To estimate the role of spontaneous oscillations in odor encoding, we trained the snail to avoid cineole, using paired presentations of cineole and electric shock. Elaboration of conditioned aversion to cineole applications resulted in distinct pairing-specific changes in behavior of the snails and procerebral activity. Responses to odor (cineole) applications were not different in amplitude or frequency of spontaneous oscillations in control and trained snails, whereas ratio of amplitudes of the same oscillation wave in proximal and distal regions of the procerebrum was significantly different in control and aversively trained snails, reflecting changes in neural firing in certain areas of the olfactory lobe.<\/jats:p>","DOI":"10.1101\/lm.32500","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T00:00:34Z","timestamp":1027728034000},"page":"422-432","source":"Crossref","is-referenced-by-count":39,"title":["Optical Recording of Odor-Evoked Responses in the Olfactory Brain of the Na\u0131\u0308ve and Aversively Trained Terrestrial Snails"],"prefix":"10.1101","volume":"7","author":[{"given":"Eugeny S.","family":"Nikitin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pavel M.","family":"Balaban","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"246","published-online":{"date-parts":[[2000,11,1]]},"reference":[{"key":"2021111106034892000_7.6.422.1","doi-asserted-by":"publisher","DOI":"10.1016\/0301-0082(93)90038-T"},{"key":"2021111106034892000_7.6.422.2","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1007\/BF00234116","article-title":"Long-term sensitization and environmental conditioning in terrestrial snails.","volume":"96","author":"Balaban","year":"1993","journal-title":"Exp. Brain Res."},{"key":"2021111106034892000_7.6.422.3","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(87)91371-0"},{"key":"2021111106034892000_7.6.422.4","doi-asserted-by":"crossref","first-page":"2930","DOI":"10.1523\/JNEUROSCI.05-11-02930.1985","article-title":"Responses to odors mapped in snail tentacle and brain by [14C]-2-deoxyglucose autoradiography.","volume":"5","author":"Chase","year":"1985","journal-title":"J. Neurosci."},{"key":"2021111106034892000_7.6.422.5","doi-asserted-by":"publisher","DOI":"10.1002\/jemt.1070240303"},{"key":"2021111106034892000_7.6.422.6","doi-asserted-by":"publisher","DOI":"10.1038\/331112a0"},{"key":"2021111106034892000_7.6.422.7","doi-asserted-by":"publisher","DOI":"10.1007\/BF00657543"},{"key":"2021111106034892000_7.6.422.8","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.91.2.669"},{"key":"2021111106034892000_7.6.422.9","doi-asserted-by":"crossref","first-page":"2677","DOI":"10.1152\/jn.1998.79.5.2677","article-title":"Minimal model of oscillation and waves in the Limax olfactory lobe with tests of model's predictive power.","volume":"79","author":"Ermentrout","year":"1998","journal-title":"J. Neurophysiol."},{"key":"2021111106034892000_7.6.422.10","doi-asserted-by":"publisher","DOI":"10.1007\/s003590050252"},{"key":"2021111106034892000_7.6.422.11","unstructured":"Gelperin A. (1989) Neurons and networks for learning about odors. in Perspectives in neural systems and behavior, eds Carew T.J. Kelly D.B. (Liss, New York), pp 121\u2013136."},{"key":"2021111106034892000_7.6.422.12","doi-asserted-by":"publisher","DOI":"10.1038\/345437a0"},{"key":"2021111106034892000_7.6.422.13","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1152\/jn.1996.76.2.1327","article-title":"Central and reflex neuronal responses elicited by odor in a terrestrial mollusk.","volume":"76","author":"Gervais","year":"1996","journal-title":"J. Neurophysiol."},{"key":"2021111106034892000_7.6.422.14","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1007\/BF00247583","article-title":"Centrifugal regulation of neuronal activity in the olfactory bulb of the walking rabbit as revealed by reversible cryogenic blockade.","volume":"69","author":"Gray","year":"1988","journal-title":"Exp. Brain. Res."},{"key":"2021111106034892000_7.6.422.15","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1113\/jphysiol.1974.sp010773","article-title":"Responses of olfactory bulb neurons to odor stimulation of small nasal areas in the salamander.","volume":"243","author":"Kauer","year":"1974","journal-title":"J. Physiol."},{"key":"2021111106034892000_7.6.422.16","doi-asserted-by":"crossref","first-page":"1851","DOI":"10.1242\/jeb.200.13.1851","article-title":"Comparative study on neural oscillation in the PC of the terrestrial slugs Incilaria bilineata and Limax marginatus.","volume":"200","author":"Kawahara","year":"1997","journal-title":"J. Exp. Biol."},{"key":"2021111106034892000_7.6.422.17","doi-asserted-by":"publisher","DOI":"10.1101\/lm.4.5.376"},{"key":"2021111106034892000_7.6.422.18","doi-asserted-by":"publisher","DOI":"10.1101\/lm.4.5.389"},{"key":"2021111106034892000_7.6.422.19","doi-asserted-by":"publisher","DOI":"10.1101\/lm.4.5.365"},{"key":"2021111106034892000_7.6.422.20","doi-asserted-by":"publisher","DOI":"10.1126\/science.265.5180.1872"},{"key":"2021111106034892000_7.6.422.21","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1242\/jeb.167.1.15","article-title":"Characterization of oscillatory olfactory interneurons in the protocerebrum of the crayfish.","volume":"167","author":"Mellon","year":"1992","journal-title":"J. Exp. Biol."},{"key":"2021111106034892000_7.6.422.22","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9861(19970804)384:3<359::AID-CNE4>3.0.CO;2-2"},{"key":"2021111106034892000_7.6.422.23","doi-asserted-by":"crossref","first-page":"1940","DOI":"10.1152\/jn.1993.69.6.1940","article-title":"Cultured olfactory interneurons from Limax maximus: Optical and electrophysiological studies of transmitter-evoked responses.","volume":"69","author":"Rhines","year":"1993","journal-title":"J. Neurophysiol."},{"key":"2021111106034892000_7.6.422.24","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1073\/pnas.78.1.640","article-title":"One-trial associative learning modifies food preferences of a terrestrial mollusk.","volume":"79","author":"Sahley","year":"1981","journal-title":"Proc. Natl. Acad. Sci."},{"key":"2021111106034892000_7.6.422.25","doi-asserted-by":"publisher","DOI":"10.1038\/35004588"},{"key":"2021111106034892000_7.6.422.26","doi-asserted-by":"crossref","unstructured":"Teyke T. Gelperin A. (1999) Olfactory oscillations augment odor discrimination not odor identification by Limax. CNS NeuroReport 10: 1061\u20131068.","DOI":"10.1097\/00001756-199904060-00030"},{"key":"2021111106034892000_7.6.422.27","doi-asserted-by":"publisher","DOI":"10.1007\/s003590050427"},{"key":"2021111106034892000_7.6.422.28","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1242\/jeb.201.7.925","article-title":"Morphological characterization of the bursting and nonbursting neurons in the olfactory center of the terrestrial slug Limax marginatus.","volume":"201","author":"Watanabe","year":"1998","journal-title":"J. Exp. Biol."},{"key":"2021111106034892000_7.6.422.29","doi-asserted-by":"publisher","DOI":"10.1038\/384162a0"},{"key":"2021111106034892000_7.6.422.30","unstructured":"Zaitseva O.V. (1991) Structural organization of the tentacular sensory system in land pulmonates. in Simpler nervous systems, eds Sakharov D.A. Winlow W. (Manchester University Press, Manchester), pp 238\u2013257."},{"key":"2021111106034892000_7.6.422.31","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4695(19980605)35:3<271::AID-NEU4>3.0.CO;2-W"},{"key":"2021111106034892000_7.6.422.32","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-8166(70)80040-4"}],"container-title":["Learning &amp; Memory"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1101\/lm.32500","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,11]],"date-time":"2021-11-11T14:06:06Z","timestamp":1636639566000},"score":1,"resource":{"primary":{"URL":"http:\/\/learnmem.cshlp.org\/lookup\/doi\/10.1101\/lm.32500"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,11,1]]},"references-count":32,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2000,11,1]]}},"alternative-id":["10.1101\/lm.32500"],"URL":"https:\/\/doi.org\/10.1101\/lm.32500","relation":{},"ISSN":["1072-0502","1549-5485"],"issn-type":[{"value":"1072-0502","type":"print"},{"value":"1549-5485","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,11,1]]}}}