{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"institution":[{"name":"medRxiv"}],"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T21:44:14Z","timestamp":1778103854841,"version":"3.51.4"},"posted":{"date-parts":[[2020,3,16]]},"group-title":"Epidemiology","reference-count":59,"publisher":"openRxiv","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"accepted":{"date-parts":[[2020,4,7]]},"abstract":"<jats:p>As new cases of COVID-19 are being confirmed pressure is mounting to increase understanding of the factors underlying the spread the disease. Using data on local transmissions until the 23rd of March 2020, we develop an ensemble of 200 ecological niche models to project monthly variation in climate suitability for spread of SARS-CoV-2 throughout a typical climatological year. Although cases of COVID-19 are reported all over the world, most outbreaks display a pattern of clustering in relatively cool and dry areas. The predecessor SARS-CoV-1 was linked to similar climate conditions. Should the spread of SARS CoV-2 continue to follow current trends, asynchronous seasonal global outbreaks could be expected. According to the models, temperate warm and cold climates are more favorable to spread of the virus, whereas arid and tropical climates are less favorable. However, model uncertainties are still high across much of sub-Saharan Africa, Latin America and South East Asia. While models of epidemic spread utilize human demography and mobility as predictors, climate can also help constrain the virus. This is because the environment can mediate human-to-human transmission of SARS-CoV-2, and unsuitable climates can cause the virus to destabilize quickly, hence reducing its capacity to become epidemic.<\/jats:p>","DOI":"10.1101\/2020.03.12.20034728","type":"posted-content","created":{"date-parts":[[2020,3,16]],"date-time":"2020-03-16T11:59:28Z","timestamp":1584359968000},"source":"Crossref","is-referenced-by-count":128,"title":["Spread of SARS-CoV-2 Coronavirus likely constrained by climate"],"prefix":"10.64898","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5107-7265","authenticated-orcid":false,"given":"Miguel B.","family":"Ara\u00fajo","sequence":"first","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5431-2729","authenticated-orcid":false,"given":"Babak","family":"Naimi","sequence":"additional","affiliation":[]}],"member":"54368","reference":[{"key":"2020112114100487000_2020.03.12.20034728v3.1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1228282"},{"key":"2020112114100487000_2020.03.12.20034728v3.2","doi-asserted-by":"crossref","first-page":"5197","DOI":"10.1038\/s41467-019-12995-9","article-title":"Climate shapes mammal community trophic structures and humans simplify them","volume":"10","year":"2019","journal-title":"Nature Communications"},{"key":"2020112114100487000_2020.03.12.20034728v3.3","unstructured":"A. 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