{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"institution":[{"name":"medRxiv"}],"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T08:39:51Z","timestamp":1768552791202,"version":"3.49.0"},"posted":{"date-parts":[[2021,7,7]]},"group-title":"Ophthalmology","reference-count":67,"publisher":"openRxiv","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"accepted":{"date-parts":[[2022,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>The aim of this study was to estimate the prevalence and causes of vision impairment (VI) in Portugal.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                  <jats:title>Setting<\/jats:title>\n                  <jats:p>Information about people with VI was obtained from Primary Care Centres, blind association (ACAPO) and from hospitals (the PCVIP-study) in the Northwest of Portugal during a period spanning years 2014-2015. Causes of VI were obtained from hospitals.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                  <jats:title>Participants<\/jats:title>\n                  <jats:p>Administrative and medical records of people with visual acuity in the better seeing eye of 0.5 decimal (0.30logMAR) or worse and\/or visual field less than 20 degrees were investigated. Capture-recapture with log-linear models was applied to estimate the number of individuals missing from lists of cases obtained from available sources.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                  <jats:title>Primary and secondary outcome measures<\/jats:title>\n                  <jats:p>Log-linear models were used to estimate the crude prevalence and the category specific prevalence of VI.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Crude prevalence of VI was 1.97% (95%CI=1.56-2.54), and standardized prevalence was 1% (95%CI=0.78-1.27). The age-specific prevalence was 3.27% (95% CI=2.36-4.90), older than 64 years, 0.64% (95%CI=0.49-0.88), aged 25-64 years, and 0.07% (95%CI=0.045-0.13), aged less than 25 years. The female-to-male ratio was1.3, that is, higher prevalence amongst females. The five leading causes of VI were Diabetic Retinopathy, Cataract, Age-related Macular Degeneration, Glaucoma and Disorders of the Globe.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>The prevalence of VI in Portugal was within the expected range and in line with other European countries. A significant number of cases of VI might be due to preventable cases and, therefore, a reduction of the prevalence of VI in Portugal seems possible. Women and old people were more likely to have VI and, therefore, these groups require extra attention. Future studies are necessary to characterize temporal changes in prevalence of VI in Portugal.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                  <jats:title>Strengths and limitations of this study<\/jats:title>\n                  <jats:list list-type=\"bullet\">\n                    <jats:list-item>\n                      <jats:p>Medical records and registers of people with vision impairment were used to determine the number of cases in these sources.<\/jats:p>\n                    <\/jats:list-item>\n                    <jats:list-item>\n                      <jats:p>Data from 3 sources (lists) with records about people with vision impairment were combined using log-linear models to determine the number of \u201cuncaptured\u201d cases.<\/jats:p>\n                    <\/jats:list-item>\n                    <jats:list-item>\n                      <jats:p>Capture-recapture methods were used to determine the prevalence of vision impairment in the Northwest Portugal.<\/jats:p>\n                    <\/jats:list-item>\n                    <jats:list-item>\n                      <jats:p>Capture-recapture methods to compute prevalence are more accurate than pure case counting from lists and more affordable than cross-sectional studies.<\/jats:p>\n                    <\/jats:list-item>\n                    <jats:list-item>\n                      <jats:p>A limitation of the current study was the low completeness, that is, the number of cases captured compared with the number of uncaptured cases.<\/jats:p>\n                    <\/jats:list-item>\n                  <\/jats:list>\n                <\/jats:sec>","DOI":"10.1101\/2021.07.06.21260069","type":"posted-content","created":{"date-parts":[[2021,7,7]],"date-time":"2021-07-07T22:00:16Z","timestamp":1625695216000},"source":"Crossref","is-referenced-by-count":1,"title":["A cross-sectional study investigating the prevalence and causes of vision impairment in Northwest Portugal using capture-recapture"],"prefix":"10.64898","author":[{"given":"Pedro Lima","family":"Ramos","sequence":"first","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1370-3242","authenticated-orcid":false,"given":"Rui","family":"Santana","sequence":"additional","affiliation":[]},{"given":"Ana Patr\u00edcia","family":"Marques","sequence":"additional","affiliation":[]},{"given":"In\u00eas","family":"Sousa","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8374-0298","authenticated-orcid":false,"given":"Am\u00e2ndio","family":"Rocha-Sousa","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3436-2010","authenticated-orcid":false,"given":"Antonio Filipe","family":"Macedo","sequence":"additional","affiliation":[]}],"member":"54368","reference":[{"key":"2022080309050622000_2021.07.06.21260069v2.1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-3768.2008.01191.x"},{"key":"2022080309050622000_2021.07.06.21260069v2.2","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.120.6.774"},{"issue":"8","key":"2022080309050622000_2021.07.06.21260069v2.3","doi-asserted-by":"crossref","first-page":"e783","DOI":"10.1111\/aos.13430","article-title":"Visual and health outcomes, measured with the activity inventory and the EQ-5D, in visual impairment","volume":"95","year":"2017","journal-title":"Acta Ophthalmol"},{"key":"2022080309050622000_2021.07.06.21260069v2.4","doi-asserted-by":"crossref","unstructured":"Hern\u00e1ndez-Moreno L , Senra H , et al. 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