{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"institution":[{"name":"medRxiv"}],"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T13:23:04Z","timestamp":1768569784367,"version":"3.49.0"},"posted":{"date-parts":[[2025,4,4]]},"group-title":"Health Economics","reference-count":23,"publisher":"openRxiv","license":[{"start":{"date-parts":[[2025,4,4]],"date-time":"2025-04-04T00:00:00Z","timestamp":1743724800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"accepted":{"date-parts":[[2025,4,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Diabetes mellitus can increase hospitalization time, requiring a multidisciplinary team and specific, high-cost supplies. In this context, the study aimed to analyze the total costs, including hospital services and professional services, of hospitalizations of patients with diabetes mellitus in Brazil between 2013 and 2023.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>This is a time series study developed using secondary data collected from the Hospital Information System. Data collection focused on the annual costs recorded by Brazil\u2019s Unified Health System for hospitalizations of patients with diabetes mellitus between 2013 and 2023, categorized by Brazilian states.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>When analyzing total costs in relation to each state\u2019s Gross Domestic Product, the scenario highlights the Northeast and North regions. Hospital service costs stand out compared to professional service costs.<\/jats:p>\n                <\/jats:sec>\n                <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Diabetes mellitus requires significant investments in continuous treatments, medications, and specialized healthcare services. Beyond the financial impact, the losses for both society and individuals are considerable.<\/jats:p>\n                <\/jats:sec>","DOI":"10.1101\/2025.04.02.25325157","type":"posted-content","created":{"date-parts":[[2025,4,8]],"date-time":"2025-04-08T09:16:24Z","timestamp":1744103784000},"source":"Crossref","is-referenced-by-count":1,"title":["Hospitalization costs of patients with diabetes mellitus in Brazil, from 2013 to 2023: a time series study"],"prefix":"10.64898","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6103-0842","authenticated-orcid":false,"given":"Luciana Lima","family":"de Ara\u00fajo","sequence":"first","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8673-0009","authenticated-orcid":false,"given":"Thaiza Teixeira Xavier","family":"Nobre","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0304-2639","authenticated-orcid":false,"given":"Ketyllem Tayanne da Silva","family":"Costa","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0009-0002-1995-1407","authenticated-orcid":false,"given":"Maria Alice","family":"da Silva Oliveira","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5578-5413","authenticated-orcid":false,"given":"Maria Eduarda Silva","family":"do Nascimento","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6290-9365","authenticated-orcid":false,"given":"Richardson Augusto","family":"Rosendo da Silva","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4105-7535","authenticated-orcid":false,"given":"Kleyton Santos","family":"de Medeiros","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2654-0497","authenticated-orcid":false,"given":"Clemente Neves","family":"Sousa","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8278-3808","authenticated-orcid":false,"given":"Aurora del Carmen Rosell","family":"Soria","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9015-211X","authenticated-orcid":false,"given":"Ana Elza Oliveira","family":"de Mendon\u00e7a","sequence":"additional","affiliation":[]}],"member":"54368","reference":[{"key":"2025043020054829000_2025.04.02.25325157v1.1","doi-asserted-by":"publisher","DOI":"10.1111\/jdi.12932"},{"issue":"2","key":"2025043020054829000_2025.04.02.25325157v1.2","doi-asserted-by":"crossref","first-page":"305","DOI":"10.5123\/S1679-49742015000200013","article-title":"Preval\u00eancia de diabetes autorreferido no Brasil: resultados da Pesquisa Nacional de Sa\u00fade 2013","volume":"24","year":"2015","journal-title":"Epidemiol. 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