{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T22:35:27Z","timestamp":1792794927395,"version":"4.5.0"},"reference-count":116,"publisher":"Cold Spring Harbor Laboratory","issue":"2","funder":[{"name":"U.S. Department of Energy, Office of Science, Office of Biological and Environmental Research","award":["DE-SC0018244"],"award-info":[{"award-number":["DE-SC0018244"]}],"id":[{"id":"https:\/\/ror.org\/0114b2m14","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Lam Laboratory","award":["#12116"],"award-info":[{"award-number":["#12116"]}]},{"name":"New Jersey Agricultural Experiment Station at Rutgers University"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Genome Res."],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:p>\n                    Rootless plants in the genus\n                    <jats:italic>Wolffia<\/jats:italic>\n                    are some of the fastest growing known plants on Earth.\n                    <jats:italic>Wolffia<\/jats:italic>\n                    have a reduced body plan, primarily multiplying through a budding type of asexual reproduction. Here, we generated draft reference genomes for\n                    <jats:italic>Wolffia australiana<\/jats:italic>\n                    (Benth.) Hartog &amp; Plas, which has the smallest genome size in the genus at 357 Mb and has a reduced set of predicted protein-coding genes at about 15,000. Comparison between multiple high-quality draft genome sequences from\n                    <jats:italic>W. australiana<\/jats:italic>\n                    clones confirmed loss of several hundred genes that are highly conserved among flowering plants, including genes involved in root developmental and light signaling pathways.\n                    <jats:italic>Wolffia<\/jats:italic>\n                    has also lost most of the conserved nucleotide-binding leucine-rich repeat (NLR) genes that are known to be involved in innate immunity, as well as those involved in terpene biosynthesis, while having a significant overrepresentation of genes in the sphingolipid pathways that may signify an alternative defense system. Diurnal expression analysis revealed that only 13% of\n                    <jats:italic>Wolffia<\/jats:italic>\n                    genes are expressed in a time-of-day (TOD) fashion, which is less than the typical \u223c40% found in several model plants under the same condition. In contrast to the model plants\n                    <jats:italic>Arabidopsis<\/jats:italic>\n                    and rice, many of the pathways associated with multicellular and developmental processes are not under TOD control in\n                    <jats:italic>W. australiana<\/jats:italic>\n                    , where genes that cycle the conditions tested predominantly have carbon processing and chloroplast-related functions. The\n                    <jats:italic>Wolffia<\/jats:italic>\n                    genome and TOD expression data set thus provide insight into the interplay between a streamlined plant body plan and optimized growth.\n                  <\/jats:p>","DOI":"10.1101\/gr.266429.120","type":"journal-article","created":{"date-parts":[[2020,12,23]],"date-time":"2020-12-23T18:19:03Z","timestamp":1608747543000},"page":"225-238","source":"Crossref","is-referenced-by-count":86,"title":["Genome and time-of-day transcriptome of\n                    <i>Wolffia australiana<\/i>\n                    link morphological minimization with gene loss and less growth control"],"prefix":"10.1101","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6272-2875","authenticated-orcid":false,"given":"Todd P.","family":"Michael","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4213-136X","authenticated-orcid":false,"given":"Evan","family":"Ernst","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nolan","family":"Hartwick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0936-501X","authenticated-orcid":false,"given":"Philomena","family":"Chu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9773-6545","authenticated-orcid":false,"given":"Douglas","family":"Bryant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3458-1347","authenticated-orcid":false,"given":"Sarah","family":"Gilbert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8655-0112","authenticated-orcid":false,"given":"Stefan","family":"Ortleb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3076-9489","authenticated-orcid":false,"given":"Erin L.","family":"Baggs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1356-3406","authenticated-orcid":false,"given":"K. Sowjanya","family":"Sree","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6385-6645","authenticated-orcid":false,"given":"Klaus J.","family":"Appenroth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4171-5371","authenticated-orcid":false,"given":"Joerg","family":"Fuchs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5741-4931","authenticated-orcid":false,"given":"Florian","family":"Jupe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0012-7223","authenticated-orcid":false,"given":"Justin 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