{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T22:12:42Z","timestamp":1781043162053,"version":"3.54.1"},"reference-count":104,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2002,6,1]],"date-time":"2002-06-01T00:00:00Z","timestamp":1022889600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2002,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Plants have evolved different but interconnected strategies to defend themselves against herbivorous insects and microbial pathogens. We used an Arabidopsis\/Pseudomonas syringaepathosystem to investigate the impact of pathogen-induced defense responses on cabbage looper (Trichoplusia ni) larval feeding. Arabidopsis mutants [npr1,pad4, eds5, andsid2(eds16)] or transgenic plants (nahG) that are more susceptible to microbial pathogens and are compromised in salicylic acid (SA)-dependent defense responses exhibited reduced levels of feeding by T. ni compared with wild-type plants. Consistent with these results, Arabidopsis mutants that are more resistant to microbial pathogens and have elevated levels of SA (cpr1 and cpr6) exhibited enhanced levels of T. ni feeding. These experiments suggested an inverse relationship between an active SA defense pathway and insect feeding. In contrast to these results, there was increased resistance toT. ni in wild-type Arabidopsis ecotype Columbia plants that were infected with P. syringae pv.maculicola strain ES4326 (Psm ES4326) expressing the avirulence genes avrRpt2 oravrB, which elicit a hypersensitive response, high levels of SA accumulation, and systemic acquired resistance to bacterial infection. Similar results were obtained with other ecotypes, including Landsberg erecta, Cape Verdi Islands, and Shakdara. When infected with PsmES4326(avrRpt2) or PsmES4326(avrB), nahG transgenic andnpr1 mutant plants (which are more susceptible to virulent and avirulent P. syringae strains) failed to show the increased insect resistance exhibited by wild-type plants. It was surprising that wild-type plants, as well as nahGand npr1 plants, infected with Psm ES4326 not expressing avrRpt2 or avrB, which elicits disease, became more susceptible to T. ni. Our results suggest two potentially novel systemic signaling pathways: a systemic response elicited by HR that leads to enhanced T. ni resistance and overrides the SA-mediated increase in T. ni susceptibility, and a SA-independent systemic response induced by virulent pathogens that leads to enhanced susceptibility to T. ni.<\/jats:p>","DOI":"10.1104\/pp.010815","type":"journal-article","created":{"date-parts":[[2002,7,28]],"date-time":"2002-07-28T18:44:09Z","timestamp":1027881849000},"page":"551-564","source":"Crossref","is-referenced-by-count":92,"title":["Signals Involved in Arabidopsis Resistance to\n                    <i>Trichoplusia ni<\/i>\n                    Caterpillars Induced by Virulent and Avirulent Strains of the Phytopathogen\n                    <i>Pseudomonas syringae<\/i>\n                    \u00a0"],"prefix":"10.1093","volume":"129","author":[{"given":"Jianping","family":"Cui","sequence":"first","affiliation":[{"name":"Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts 02138 (J.C., L.R.R., P.D.K., N.E.P.);"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georg","family":"Jander","sequence":"additional","affiliation":[{"name":"Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115 (G.J., F.M.A.); and"},{"name":"Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts 02114 (G.J., F.M.A.)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa R.","family":"Racki","sequence":"additional","affiliation":[{"name":"Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts 02138 (J.C., L.R.R., P.D.K., N.E.P.);"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul D.","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts 02138 (J.C., L.R.R., P.D.K., N.E.P.);"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naomi E.","family":"Pierce","sequence":"additional","affiliation":[{"name":"Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts 02138 (J.C., L.R.R., P.D.K., N.E.P.);"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederick M.","family":"Ausubel","sequence":"additional","affiliation":[{"name":"Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115 (G.J., F.M.A.); and"},{"name":"Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts 02114 (G.J., F.M.A.)"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2002,6,1]]},"reference":[{"key":"2021062512551823500_R1","doi-asserted-by":"crossref","first-page":"10306","DOI":"10.1073\/pnas.95.17.10306","article-title":"Different requirements for EDS1 and NDR1 by disease resistance genes define at least two R gene mediated signaling pathways in Arabidopsis.","volume":"95","author":"Aarts","year":"1998","journal-title":"Proc Natl Acad Sci USA"},{"key":"2021062512551823500_R2","doi-asserted-by":"crossref","first-page":"2148","DOI":"10.1126\/science.284.5423.2148","article-title":"EIN2, a bifunctional transducer of ethylene and stress responses in Arabidopsis.","volume":"284","author":"Alonso","year":"1999","journal-title":"Science"},{"key":"2021062512551823500_R3","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1094\/MPMI.2001.14.2.181","article-title":"Mutational analysis of the Arabidopsis RPS2 disease resistance gene and the corresponding Pseudomonas syringae avrRpt2 avirulence gene.","volume":"14","author":"Axtell","year":"2001","journal-title":"Mol Plant-Microbe Interact"},{"key":"2021062512551823500_R4","doi-asserted-by":"crossref","first-page":"8113","DOI":"10.1073\/pnas.95.14.8113","article-title":"Jasmonate-induced responses are costly but benefit plants under attack in native populations.","volume":"95","author":"Baldwin","year":"1998","journal-title":"Proc Natl Acad Sci USA"},{"key":"2021062512551823500_R5","doi-asserted-by":"crossref","first-page":"2281","DOI":"10.1126\/science.1061337","article-title":"Evolutionary dynamics of plant R-genes.","volume":"292","author":"Bergelson","year":"2001","journal-title":"Science"},{"key":"2021062512551823500_R6","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0014-5793(98)01251-4","article-title":"Wounding and chemicals induce expression of the Arabidopsis thaliana gene THI2.1, encoding a fungal defense thionin, via the octadecanoid pathway.","volume":"437","author":"Bohlmann","year":"1998","journal-title":"FEBS Lett"},{"key":"2021062512551823500_R7","first-page":"1573","article-title":"The cpr5 mutant of Arabidopsis expresses both NPR1-dependent and NPR1-independent resistance.","volume":"9","author":"Bowling","year":"1997","journal-title":"Plant Cell"},{"key":"2021062512551823500_R8","first-page":"1845","article-title":"A mutation in Arabidopsis that leads to constitutive expression of systemic acquired resistance.","volume":"6","author":"Bowling","year":"1994","journal-title":"Plant Cell"},{"key":"2021062512551823500_R9","doi-asserted-by":"crossref","first-page":"15849","DOI":"10.1073\/pnas.95.26.15849","article-title":"The Arabidopsis thaliana RPM1 disease resistance gene product is a peripheral plasma membrane protein that is degraded coincident with the hypersensitive response.","volume":"95","author":"Boyes","year":"1998","journal-title":"Proc Natl Acad Sci USA"},{"key":"2021062512551823500_R10","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.2307\/3869945","article-title":"Characterization of an Arabidopsis mutant that is nonresponsive to inducers of systemic acquired resistance.","volume":"6","author":"Cao","year":"1994","journal-title":"Plant Cell"},{"key":"2021062512551823500_R11","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S0092-8674(00)81858-9","article-title":"The Arabidopsis NPR1 gene that controls systemic acquired resistance encodes a novel protein containing ankyrin repeats.","volume":"88","author":"Cao","year":"1997","journal-title":"Cell"},{"key":"2021062512551823500_R12","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1086\/394440","article-title":"The problem of acquired physiological immunity in plants.","volume":"8","author":"Chester","year":"1933","journal-title":"Quart Rev Biol"},{"key":"2021062512551823500_R13","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1105\/tpc.10.4.557","article-title":"Uncoupling PR gene expression from NPR1 and bacterial resistance: characterization of the dominant Arabidopsis cpr6-1 mutant.","volume":"10","author":"Clarke","year":"1998","journal-title":"Plant Cell"},{"key":"2021062512551823500_R14","doi-asserted-by":"crossref","first-page":"2175","DOI":"10.1105\/tpc.12.11.2175","article-title":"Roles of salicylic acid, jasmonic acid, and ethylene in cpr-induced resistance in Arabidopsis.","volume":"12","author":"Clarke","year":"2000","journal-title":"Plant Cell"},{"key":"2021062512551823500_R15","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1046\/j.1365-313X.1991.t01-7-00999.x","article-title":"Identification and molecular mapping of a single Arabidopsis thaliana locus determining resistance to a phytopathogenic Pseudomonas syringae isolate.","volume":"1","author":"Debener","year":"1991","journal-title":"Plant J"},{"key":"2021062512551823500_R16","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1126\/science.266.5188.1247","article-title":"A central role of salicylic acid in plant disease resistance.","volume":"266","author":"Delaney","year":"1994","journal-title":"Science"},{"key":"2021062512551823500_R17","doi-asserted-by":"crossref","first-page":"6602","DOI":"10.1073\/pnas.92.14.6602","article-title":"Arabidopsis signal transduction mutant defective in chemically and biologically induced disease resistance.","volume":"92","author":"Delaney","year":"1995","journal-title":"Proc Natl Acad Sci USA"},{"key":"2021062512551823500_R18","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1046\/j.1365-313x.2000.00870.x","article-title":"Three unique mutants of Arabidopsis identify eds loci required for limiting growth of a biotrophic fungal pathogen.","volume":"24","author":"Dewdney","year":"2000","journal-title":"Plant J"},{"key":"2021062512551823500_R19","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/0092-8674(94)90218-6","article-title":"Arabidopsis mutants simulating disease resistance response.","volume":"77","author":"Dietrich","year":"1994","journal-title":"Cell"},{"key":"2021062512551823500_R20","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0065-2660(08)60527-1","article-title":"Activation, structure and organization of genes involved in microbial defense in plants.","volume":"28","author":"Dixon","year":"1990","journal-title":"Adv Genet"},{"key":"2021062512551823500_R21","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1146\/annurev.py.32.090194.002403","article-title":"Early events in the activation of plant defense responses.","volume":"32","author":"Dixon","year":"1994","journal-title":"Annu Rev Phytopathol"},{"key":"2021062512551823500_R22","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1104\/pp.108.4.1741","article-title":"Salicylic acid inhibits synthesis of proteinase inhibitors in tomato leaves induced by systemin and jasmonic acid.","volume":"108","author":"Doares","year":"1995","journal-title":"Plant Physiol"},{"key":"2021062512551823500_R23","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/0885-5765(88)90004-5","article-title":"The wound response in tomato plants can be inhibited by aspirin and related hyrodxybenzoic acid.","volume":"33","author":"Doherty","year":"1988","journal-title":"Physiol Mol Plant Pathol"},{"key":"2021062512551823500_R24","first-page":"61","article-title":"Induction of Arabidopsis defense genes by virulent and avirulent Pseudomonas syringae strains and by a cloned avirulence gene.","volume":"3","author":"Dong","year":"1991","journal-title":"Plant Cell"},{"key":"2021062512551823500_R25","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/1369-5266(88)80053-0","article-title":"SA, JA, ethylene, and disease resistance in plants.","volume":"1","author":"Dong","year":"1998","journal-title":"Curr Opin Plant Biol"},{"key":"2021062512551823500_R26","doi-asserted-by":"crossref","first-page":"3292","DOI":"10.1073\/pnas.96.6.3292","article-title":"EDS1, an essential component of R gene-mediated disease resistance in Arabidopsis has homology to eukaryotic lipases.","volume":"96","author":"Falk","year":"1999","journal-title":"Proc Natl Acad Sci USA"},{"key":"2021062512551823500_R27","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/S0960-9822(99)80140-7","article-title":"Inverse relationship between systemic resistance of plants to microorganisms and to insect herbivory.","volume":"9","author":"Felton","year":"1999","journal-title":"Curr Biol"},{"key":"2021062512551823500_R28","doi-asserted-by":"crossref","first-page":"5400","DOI":"10.1093\/emboj\/20.19.5400","article-title":"Direct interaction between the Arabidopsis disease resistance signaling proteins, EDS1 and PAD4.","volume":"20","author":"Feys","year":"2001","journal-title":"EMBO J"},{"key":"2021062512551823500_R29","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1146\/annurev.py.09.090171.001423","article-title":"Current status of the gene-for-gene concept.","volume":"9","author":"Flor","year":"1971","journal-title":"Annu Rev Phytopathol"},{"key":"2021062512551823500_R30","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1126\/science.261.5122.754","article-title":"Requirement for salicylic acid for the induction of systemic acquired resistance.","volume":"261","author":"Gaffney","year":"1993","journal-title":"Science"},{"key":"2021062512551823500_R31","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/S1369-5266(00)00177-1","article-title":"Genes controlling expression of defense responses in Arabidopsis: 2001 status.","volume":"4","author":"Glazebrook","year":"2001","journal-title":"Curr Opin Plant Biol"},{"key":"2021062512551823500_R32","doi-asserted-by":"crossref","first-page":"8955","DOI":"10.1073\/pnas.91.19.8955","article-title":"Isolation of phytoalexin-deficient mutants of Arabidopsis thaliana and characterization of their interactions with bacterial pathogens.","volume":"91","author":"Glazebrook","year":"1994","journal-title":"Proc Natl Acad Sci USA"},{"key":"2021062512551823500_R33","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1093\/genetics\/143.2.973","article-title":"Isolation of Arabidopsis mutants with enhanced disease susceptibility by direct screening.","volume":"143","author":"Glazebrook","year":"1996","journal-title":"Genetics"},{"key":"2021062512551823500_R34","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1146\/annurev.genet.31.1.547","article-title":"Use of Arabidopsis for genetic dissection of plant defense responses.","volume":"31","author":"Glazebrook","year":"1997","journal-title":"Annu Rev Genet"},{"key":"2021062512551823500_R35","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1046\/j.1365-313x.2000.00902.x","article-title":"Oxidative burst and cognate redox signaling reported by luciferase imaging: identification of a signal network that functions independently of ethylene, SA and Me-JA but is dependent on MAPKK activity.","volume":"24","author":"Grant","year":"2000","journal-title":"Plant J"},{"key":"2021062512551823500_R36","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1126\/science.7638602","article-title":"Structure of the Arabidopsis RPM1 gene which enables dual-specificity disease resistance.","volume":"269","author":"Grant","year":"1995","journal-title":"Science"},{"key":"2021062512551823500_R37","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1093\/ee\/25.1.135","article-title":"Effects of ultraviolet B exposure of Arabidopsis thaliana on herbivory by two crucifer-feeding insects.","volume":"25","author":"Grant-Peterson","year":"1996","journal-title":"Environ Entomol"},{"key":"2021062512551823500_R38","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1046\/j.1365-313X.1993.04020327.x","article-title":"Arabidopsis mutants compromised for the control of cellular damage during pathogenesis and aging.","volume":"4","author":"Greenberg","year":"1993","journal-title":"Plant J"},{"key":"2021062512551823500_R39","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/0092-8674(94)90217-8","article-title":"Programmed cell death in plants: a pathogen-triggered response activated coordinately with multiple defense functions.","volume":"77","author":"Greenberg","year":"1994","journal-title":"Cell"},{"key":"2021062512551823500_R40","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/B978-0-12-326450-3.50016-4","article-title":"Insect development in the transmission of bacterial pathogens.","volume-title":"Vectors of Plant Pathogens.","author":"Harrison","year":"1980"},{"key":"2021062512551823500_R41","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1046\/j.1365-2745.2000.00476.x","article-title":"On integrating molecular and ecological studies of plant resistance: variety of mechanisms and breadth of antagonists.","volume":"88","author":"Hatcher","year":"2000","journal-title":"J Ecol"},{"key":"2021062512551823500_R42","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1023\/A:1026592509060","article-title":"Hypersensitive response-related death.","volume":"44","author":"Heath","year":"2000","journal-title":"Plant Mol Biol"},{"key":"2021062512551823500_R43","first-page":"2067","article-title":"An octadecanoid pathway mutant (JL5) of tomato is compromised in signaling for defense against insect attack.","volume":"8","author":"Howe","year":"1996","journal-title":"Plant Cell"},{"key":"2021062512551823500_R44","doi-asserted-by":"crossref","first-page":"4859","DOI":"10.1128\/jb.175.15.4859-4869.1993","article-title":"Molecular analysis of avirulence gene avrRpt2 and identification of a putative regulatory sequence common to all known Pseudomonas syrnigae avirulence genes.","volume":"175","author":"Innes","year":"1993","journal-title":"J Bacteriol"},{"key":"2021062512551823500_R45","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1046\/j.1365-313X.1993.04050813.x","article-title":"Identification of a disease resistance locus in Arabidopsis that is functionally homologous to the RPG1 locus of soybean.","volume":"4","author":"Innes","year":"1993","journal-title":"Plant J"},{"key":"2021062512551823500_R46","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1104\/pp.126.2.890","article-title":"The TASTY locus on Chromosome 1 of Arabidopsis affects feeding of the insect herbivore Trichoplusia ni.","volume":"126","author":"Jander","year":"2001","journal-title":"Plant Physiol"},{"key":"2021062512551823500_R47","first-page":"53","article-title":"Microorganisms as mediators of plant resource exploitation by insect herbivores.","volume-title":"A New Ecology: Novel Approaches to Interactive Systems.","author":"Jones","year":"1984"},{"key":"2021062512551823500_R48","doi-asserted-by":"crossref","first-page":"4677","DOI":"10.1002\/j.1460-2075.1992.tb05572.x","article-title":"Rapid activation of a novel plant defense gene is strictly dependent on the Arabidopsis RPM1 disease resistance locus.","volume":"11","author":"Kiedrowski","year":"1992","journal-title":"EMBO J"},{"key":"2021062512551823500_R49","first-page":"301","article-title":"Two simple media for the demonstration of phycocyanin and fluorescin.","volume":"44","author":"King","year":"1954","journal-title":"J Lab Clin Med"},{"key":"2021062512551823500_R50","doi-asserted-by":"crossref","first-page":"8849","DOI":"10.1073\/pnas.97.16.8849","article-title":"Nitric oxide and salicylic acid signaling in plant defense.","volume":"97","author":"Klessig","year":"2000","journal-title":"Proc Natl Acad Sci USA"},{"key":"2021062512551823500_R51","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1104\/pp.115.4.1299","article-title":"Evidence for chewing insect-specific molecular events distinct from a general wound response in leaves.","volume":"115","author":"Korth","year":"1997","journal-title":"Plant Physiol"},{"key":"2021062512551823500_R52","first-page":"865","article-title":"RPS2, an Arabidopsis disease resistance locus specifying recognition of Pseudomonas syringae strains expressing the avirulence gene avrRpt2.","volume":"5","author":"Kunkel","year":"1993","journal-title":"Plant Cell"},{"key":"2021062512551823500_R53","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1094\/MPMI-8-0863","article-title":"Systemic acquired resistance in Arabidopsis requires salicylic acid but not ethylene.","volume":"8","author":"Lawton","year":"1995","journal-title":"Mol Plant-Microbe Interact"},{"key":"2021062512551823500_R54","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1046\/j.1365-313x.2000.00744.x","article-title":"A resistance gene product of the nucleotide binding site: leucine rich repeats class can form a complex with bacterial avirulence proteins in vivo.","volume":"22","author":"Leister","year":"2000","journal-title":"Plant J"},{"key":"2021062512551823500_R55","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/S1360-1385(99)01415-6","article-title":"Defense on multiple fronts: How do plants cope with diverse enemies?","volume":"4","author":"Maleck","year":"1999","journal-title":"Trends Plant Sci"},{"key":"2021062512551823500_R56","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1038\/82521","article-title":"The transcriptome of Arabidopsis thaliana during systemic acquired resistance.","volume":"26","author":"Maleck","year":"2000","journal-title":"Nat Genet"},{"key":"2021062512551823500_R57","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1023\/A:1006070413843","article-title":"The promoter of the plant defensin gene PDF1.2 from Arabidopsis is systemically activated by fungal pathogens and responds to methyl jasmonate but not to salicylic acid.","volume":"38","author":"Manners","year":"1998","journal-title":"Plant Mol Biol"},{"key":"2021062512551823500_R58","doi-asserted-by":"crossref","first-page":"5473","DOI":"10.1073\/pnas.94.10.5473","article-title":"Jasmonate is essential for insect defense in Arabidopsis.","volume":"94","author":"McConn","year":"1997","journal-title":"Proc Natl Acad Sci USA"},{"key":"2021062512551823500_R59","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/S0968-0004(99)01532-7","article-title":"Signal transduction in the plant immune response.","volume":"25","author":"McDowell","year":"2000","journal-title":"Trends Biochem Sci"},{"key":"2021062512551823500_R60","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1094\/MPMI-6-453","article-title":"Spatial and temporal accumulation of defense gene transcripts in bean (Phaseolus vulgaris) leaves in relation to bacteria-induced hypersensitive cell death.","volume":"6","author":"Meier","year":"1993","journal-title":"Mol Plant-Microbe Interact"},{"key":"2021062512551823500_R61","first-page":"1393","article-title":"Salicylic acid induction-deficient mutants of Arabidopsis express PR-2 and PR-5 and accumulate high levels of camalexin after pathogen inoculation.","volume":"11","author":"Nawrath","year":"1999","journal-title":"Plant Cell"},{"key":"2021062512551823500_R62","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1046\/j.1365-313X.1995.08020227.x","article-title":"Is hydrogen peroxide a second messenger of salicylic acid in systemic acquired resistance?","volume":"8","author":"Neuenschwander","year":"1995","journal-title":"Plant J"},{"key":"2021062512551823500_R63","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1093\/oxfordjournals.pcp.a029397","article-title":"Antagonistic effect of salicylic acid and jasmonic acid on the expression of pathogenesis-related (PR) protein genes in wounded mature tobacco leaves.","volume":"39","author":"Niki","year":"1998","journal-title":"Plant Cell Physiol"},{"key":"2021062512551823500_R64","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/S0092-8674(00)80846-6","article-title":"Eukaryotic fatty acylation drives plasma membrane targeting and enhances function of several type III effector proteins from Pseudomonas syringae.","volume":"12","author":"Nimchuk","year":"2000","journal-title":"Cell"},{"key":"2021062512551823500_R65","doi-asserted-by":"crossref","first-page":"1914","DOI":"10.1126\/science.274.5294.1914","article-title":"Ethylene as a signal mediating the wound response of tomato plants.","volume":"274","author":"O'Donnell","year":"1996","journal-title":"Science"},{"key":"2021062512551823500_R66","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1603\/0022-0493-93.3.840","article-title":"Jasmonic acid induced resistance in grapevines to a root and leaf feeder.","volume":"93","author":"Omer","year":"2000","journal-title":"J Econ Entomol"},{"key":"2021062512551823500_R67","doi-asserted-by":"crossref","first-page":"13971","DOI":"10.1073\/pnas.95.23.13971","article-title":"Concerted biosynthesis of an insect elicitor of plant volatiles.","volume":"95","author":"Pare","year":"1998","journal-title":"Proc Natl Acad Sci USA"},{"key":"2021062512551823500_R68","first-page":"2033","article-title":"Characterization of eds1, a mutation in Arabidopsis suppressing resistance to Peronospora parasitica specified by several different RPP genes.","volume":"8","author":"Parker","year":"1996","journal-title":"Plant Cell"},{"key":"2021062512551823500_R69","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/S1360-1385(00)01603-4","article-title":"Coping with multiple enemies: an integration of molecular and ecological perspectives.","volume":"5","author":"Paul","year":"2000","journal-title":"Trends Plant Sci"},{"key":"2021062512551823500_R70","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1105\/tpc.12.7.1031","article-title":"A unique 33-kD cysteine proteinase accumulates in response to larval feeding in maize genotypes resistant to fall armyworm and other Lepidoptera.","volume":"12","author":"Pechan","year":"2000","journal-title":"Plant Cell"},{"key":"2021062512551823500_R71","first-page":"123","article-title":"Aspirin prevents would-induced gene expression in tomato leaves by blocking jasmonic acid biosynthesis.","volume":"191","author":"Pen\u0303a-Corte\u0301s","year":"1993","journal-title":"Planta"},{"key":"2021062512551823500_R72","first-page":"2309","article-title":"Pathogen-induced systemic activation of a plant defensin gene in Arabidopsis follows a salicylic acid-independent pathway.","volume":"8","author":"Penninckx","year":"1996","journal-title":"Plant Cell"},{"key":"2021062512551823500_R73","doi-asserted-by":"crossref","first-page":"2103","DOI":"10.1105\/tpc.10.12.2103","article-title":"Concomitant activation of jasmonate and ethylene response pathways is required for induction of a plant defensin gene in Arabidopsis.","volume":"10","author":"Penninckx","year":"1998","journal-title":"Plant Cell"},{"key":"2021062512551823500_R74","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/S1360-1385(98)01364-8","article-title":"Salicylic acid-independent plant defense pathways.","volume":"4","author":"Pieterse","year":"1999","journal-title":"Trends Plant Sci"},{"key":"2021062512551823500_R75","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1105\/tpc.10.9.1571","article-title":"A novel signaling pathway controlling induced systemic resistance in Arabidopsis.","volume":"10","author":"Pieterse","year":"1998","journal-title":"Plant Cell"},{"key":"2021062512551823500_R76","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1007\/s004250050609","article-title":"Tobacco mosaic virus inoculation inhibits wound-induced jasmonic acid- mediated responses within but not between plants.","volume":"209","author":"Preston","year":"1999","journal-title":"Planta"},{"key":"2021062512551823500_R77","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1146\/annurev.es.11.110180.000353","article-title":"Interactions among three trophic levels: influence of plants on interactions between insect herbivores and natural enemies.","volume":"11","author":"Price","year":"1980","journal-title":"Annu Rev Ecol Syst"},{"key":"2021062512551823500_R78","first-page":"383","article-title":"Interactions among plant pathogenic prokaryotes, plants, and insect vectors.","volume-title":"Microbial Mediation of Plant-Herbivore Interactions.","author":"Purcell","year":"1991"},{"key":"2021062512551823500_R79","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1105\/tpc.11.9.1695","article-title":"The gain-of-function Arabidopsis acd6 mutant reveals novel regulation and function of the salicylic acid signaling pathway in controlling cell death, defenses, and cell growth.","volume":"11","author":"Rate","year":"1999","journal-title":"Plant Cell"},{"key":"2021062512551823500_R80","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1046\/j.1365-313x.1998.00319.x","article-title":"Correlation of defense gene induction defects with powdery mildew susceptibility in Arabidopsis enhanced disease susceptibility mutants.","volume":"16","author":"Reuber","year":"1998","journal-title":"Plant J"},{"key":"2021062512551823500_R81","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1105\/tpc.12.5.707","article-title":"Differential gene expression in response to mechanical wounding and insect feeding in Arabidopsis.","volume":"12","author":"Reymond","year":"2000","journal-title":"Plant Cell"},{"key":"2021062512551823500_R82","first-page":"305","article-title":"Arabidopsis enhanced disease susceptibility mutants exhibit enhanced susceptibility to several bacterial pathogens and alterations in PR-1 gene expression.","volume":"9","author":"Rogers","year":"1997","journal-title":"Plant Cell"},{"key":"2021062512551823500_R83","first-page":"47","article-title":"Arabidopsis thaliana enhanced disease susceptibility (eds) mutants.","volume-title":"Biology of Plant-Microbe Interactions. International Society of Molecular Plant-Microbe Interactions, St. Paul","author":"Rogers","year":"1996"},{"key":"2021062512551823500_R84","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/0042-6822(61)90318-X","article-title":"Localized acquired resistance to plant virus infection in hypersensitive hosts.","volume":"14","author":"Ross","year":"1961","journal-title":"Virology"},{"key":"2021062512551823500_R85","first-page":"425","article-title":"The Arabidopsis NIM1 protein shows homology to the mammalian transcription factor inhibitor I\u03baB.","volume":"9","author":"Ryals","year":"1997","journal-title":"Plant Cell"},{"key":"2021062512551823500_R86","doi-asserted-by":"crossref","first-page":"1809","DOI":"10.2307\/3870231","article-title":"Systemic acquired resistance.","volume":"8","author":"Ryals","year":"1996","journal-title":"Plant Cell"},{"key":"2021062512551823500_R87","doi-asserted-by":"crossref","first-page":"11655","DOI":"10.1073\/pnas.97.21.11655","article-title":"Coordinated plant defense responses in Arabidopsis revealed by microarray analysis.","volume":"97","author":"Schenk","year":"2000","journal-title":"Proc Natl Acad Sci USA"},{"key":"2021062512551823500_R88","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1094\/MPMI.1997.10.1.69","article-title":"Characterization of a salicylic acid-insensitive mutant (sai1) of Arabidopsis thaliana identified in a selective screen utilizing the SA-inducible expression of the tms2 gene.","volume":"10","author":"Shah","year":"1997","journal-title":"Mol Plant-Microbe Interact"},{"key":"2021062512551823500_R89","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1093\/aesa\/55.5.591","article-title":"The biology of Trichoplusia ni (Lepidoptera: Noctuidae): life history and behavior.","volume":"55","author":"Shorey","year":"1962","journal-title":"Ann Entomol Soc Am"},{"key":"2021062512551823500_R90","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1038\/23260","article-title":"Dynamics of disease resistance polymorphism at the RPM1 locus of Arabidopsis.","volume":"400","author":"Stahl","year":"1999","journal-title":"Nature"},{"key":"2021062512551823500_R91","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/S1369-5266(99)80048-X","article-title":"Plant-insect interactions.","volume":"2","author":"Stotz","year":"1999","journal-title":"Curr Opin Plant Biol"},{"key":"2021062512551823500_R92","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1104\/pp.124.3.1007","article-title":"Induced plant defense responses against chewing insects: Ethylene signaling reduces resistance of Arabidopsis against Egyptian cotton worm but not diamondback moth.","volume":"124","author":"Stotz","year":"2000","journal-title":"Plant Physiol"},{"key":"2021062512551823500_R93","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1006\/pmpp.1998.0193","article-title":"Signal interactions in pathogen and insect attack: systemic plant-mediated interactions between pathogens and herbivores of the tomato, Lycopersicon esculentum.","volume":"54","author":"Stout","year":"1999","journal-title":"Physiol Mol Plant Pathol"},{"key":"2021062512551823500_R94","first-page":"2541","article-title":"Mutational analysis of the Arabidopsis nucleotide binding site-leucine-rich repeat resistance gene RPS2.","volume":"12","author":"Tao","year":"2000","journal-title":"Plant Cell"},{"key":"2021062512551823500_R95","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1023\/A:1020840900595","article-title":"Trade-offs in plant defense against pathogens and herbivores: a field demonstration of chemical elicitors of induced resistance.","volume":"25","author":"Thaler","year":"1999","journal-title":"J Chem Ecol"},{"key":"2021062512551823500_R96","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1038\/35048692","article-title":"Analysis of the genome sequence of the flowering plant Arabidopsis thaliana.","volume":"408","author":"The Arabidopsis Genome Initiative","year":"2000","journal-title":"Nature"},{"key":"2021062512551823500_R97","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1094\/MPMI-6-692","article-title":"Biological induction of systemic acquired resistance in Arabidopsis.","volume":"6","author":"Uknes","year":"1993","journal-title":"Mol Plant-Microbe Interact"},{"key":"2021062512551823500_R98","doi-asserted-by":"crossref","first-page":"8711","DOI":"10.1073\/pnas.130425197","article-title":"Enhancement of induced disease resistance by simultaneous activation of salicylate- and jasmonate-dependent defense pathways in Arabidopsis thaliana.","volume":"97","author":"van Wees","year":"2000","journal-title":"Proc Natl Acad Sci USA"},{"key":"2021062512551823500_R99","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1023\/A:1006319216982","article-title":"Rhizobacteria-mediated induced systemic resistance (ISR) in Arabidopsis is not associated with a direct effect on expression of known defense-related genes but stimulates the expression of the jasmonate-inducible gene Atvsp upon challenge.","volume":"41","author":"van Wees","year":"1999","journal-title":"Plant Mol Biol"},{"key":"2021062512551823500_R100","doi-asserted-by":"crossref","first-page":"959","DOI":"10.2307\/3870006","article-title":"Salicylic acid is not the translocated signal responsible for inducing systemic acquired resistance but is required in signal transduction.","volume":"6","author":"Vernooij","year":"1994","journal-title":"Plant Cell"},{"key":"2021062512551823500_R101","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1104\/pp.96.2.390","article-title":"Differential regulation of \u03b2-1,3-glucanase messenger RNAs in response to pathogen infection.","volume":"96","author":"Ward","year":"1991","journal-title":"Plant Physiol"},{"key":"2021062512551823500_R102","first-page":"49","article-title":"Identification of Pseudomonas syringae pathogens of Arabidopsis and a bacterial locus determining avirulence on both Arabidopsis and soybean.","volume":"3","author":"Whalen","year":"1991","journal-title":"Plant Cell"},{"key":"2021062512551823500_R103","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1094\/MPMI-6-434","article-title":"Arabidopsis mutations at the RPS2 locus result in loss of resistance to Pseudomonas syringae strains expressing the avirulence gene avrRpt2.","volume":"6","author":"Yu","year":"1993","journal-title":"Mol Plant-Microbe Interact"},{"key":"2021062512551823500_R104","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1105\/tpc.10.6.1021","article-title":"PAD4 functions upstream of salicylic acid to control defense responses in Arabidopsis.","volume":"10","author":"Zhou","year":"1998","journal-title":"Plant Cell"}],"container-title":["Plant Physiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/plphys\/article-pdf\/129\/2\/551\/38688776\/plphys_v129_2_551.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/plphys\/article-pdf\/129\/2\/551\/38688776\/plphys_v129_2_551.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,25]],"date-time":"2021-06-25T09:02:00Z","timestamp":1624611720000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/plphys\/article\/129\/2\/551\/6110224"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,6,1]]},"references-count":104,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2002,6,1]]},"published-print":{"date-parts":[[2002,6,1]]}},"URL":"https:\/\/doi.org\/10.1104\/pp.010815","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.1014845.195153","asserted-by":"object"}]},"ISSN":["1532-2548","0032-0889"],"issn-type":[{"value":"1532-2548","type":"electronic"},{"value":"0032-0889","type":"print"}],"subject":[],"published-other":{"date-parts":[[2002,6,1]]},"published":{"date-parts":[[2002,6,1]]}}}