{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T11:30:10Z","timestamp":1790854210766,"version":"4.1.0"},"reference-count":78,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2011,8,2]],"date-time":"2011-08-02T00:00:00Z","timestamp":1312243200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,10,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The S locus, a single polymorphic locus, is responsible for self-incompatibility (SI) in the Brassicaceae family and many related plant families. Despite its importance, our knowledge of S-locus evolution is largely restricted to the causal genes encoding the S-locus receptor kinase (SRK) receptor and S-locus cysteine-rich protein (SCR) ligand of the SI system. Here, we present high-quality sequences of the genomic region of six S-locus haplotypes: Arabidopsis (Arabidopsis thaliana; one haplotype), Arabidopsis lyrata (four haplotypes), and Capsella rubella (one haplotype). We compared these with reference S-locus haplotypes of the self-compatible Arabidopsis and its SI congener A. lyrata. We subsequently reconstructed the likely genomic organization of the S locus in the most recent common ancestor of Arabidopsis and Capsella. As previously reported, the two SI-determining genes, SCR and SRK, showed a pattern of coevolution. In addition, consistent with previous studies, we found that duplication, gene conversion, and positive selection have been important factors in the evolution of these two genes and appear to contribute to the generation of new recognition specificities. Intriguingly, the inactive pseudo-S-locus haplotype in the self-compatible species C. rubella is likely to be an old S-locus haplotype that only very recently became fixed when C. rubella split off from its SI ancestor, Capsella grandiflora.<\/jats:p>","DOI":"10.1104\/pp.111.174912","type":"journal-article","created":{"date-parts":[[2011,8,3]],"date-time":"2011-08-03T02:52:37Z","timestamp":1312339957000},"page":"937-946","source":"Crossref","is-referenced-by-count":70,"title":["Evolution of the<i>S<\/i>-Locus Region in Arabidopsis Relatives \u00a0 \u00a0"],"prefix":"10.1093","volume":"157","author":[{"given":"Ya-Long","family":"Guo","sequence":"first","affiliation":[{"name":"Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tuebingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuan","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tuebingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christa","family":"Lanz","sequence":"additional","affiliation":[{"name":"Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tuebingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Detlef","family":"Weigel","sequence":"additional","affiliation":[{"name":"Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tuebingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2011,8,2]]},"reference":[{"key":"2021041907135563400_b1","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1007\/s002510050639","article-title":"Common chimpanzees have greater diversity than humans at two of the three highly polymorphic MHC class I genes","volume":"51","author":"Adams","year":"2000","journal-title":"Immunogenetics"},{"key":"2021041907135563400_b2","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1038\/35048692","article-title":"Analysis of the genome sequence of the flowering plant Arabidopsis thaliana","volume":"408","author":"Arabidopsis Genome Initiative","year":"2000","journal-title":"Nature"},{"key":"2021041907135563400_b3","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1038\/nrg776","article-title":"The evolution of plant sexual diversity","volume":"3","author":"Barrett","year":"2002","journal-title":"Nat Rev Genet"},{"key":"2021041907135563400_b4","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1098\/rstb.2009.0199","article-title":"Understanding plant reproductive diversity","volume":"365","author":"Barrett","year":"2010","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"key":"2021041907135563400_b5","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1093\/molbev\/msl042","article-title":"The transition to self-compatibility in Arabidopsis thaliana and evolution within S-haplotypes over 10 Myr","volume":"23","author":"Bechsgaard","year":"2006","journal-title":"Mol Biol Evol"},{"key":"2021041907135563400_b6","doi-asserted-by":"crossref","first-page":"18724","DOI":"10.1073\/pnas.0909766107","article-title":"Dated molecular phylogenies indicate a Miocene origin for Arabidopsis thaliana","volume":"107","author":"Beilstein","year":"2010","journal-title":"Proc Natl Acad Sci USA"},{"key":"2021041907135563400_b7","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1534\/genetics.109.102442","article-title":"Expression of distinct self-incompatibility specificities in Arabidopsis thaliana","volume":"182","author":"Boggs","year":"2009","journal-title":"Genetics"},{"key":"2021041907135563400_b8","doi-asserted-by":"crossref","first-page":"e1000426","DOI":"10.1371\/journal.pgen.1000426","article-title":"Independent S-locus mutations caused self-fertility in Arabidopsis thaliana","volume":"5","author":"Boggs","year":"2009","journal-title":"PLoS Genet"},{"key":"2021041907135563400_b9","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1111\/j.1558-5646.2009.00925.x","article-title":"Does mate limitation in self-incompatible species promote the evolution of selfing? 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