{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T16:12:25Z","timestamp":1792426345337,"version":"4.5.0"},"reference-count":84,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2021,1,20]],"date-time":"2021-01-20T00:00:00Z","timestamp":1611100800000},"content-version":"vor","delay-in-days":3521,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Plants have evolved sophisticated mechanisms to sense and respond to pathogen attacks. Resistance against necrotrophic pathogens generally requires the activation of the jasmonic acid (JA) signaling pathway, whereas the salicylic acid (SA) signaling pathway is mainly activated against biotrophic pathogens. SA can antagonize JA signaling and vice versa. Here, we report that the necrotrophic pathogen Botrytis cinerea exploits this antagonism as a strategy to cause disease development. We show that B. cinerea produces an exopolysaccharide, which acts as an elicitor of the SA pathway. In turn, the SA pathway antagonizes the JA signaling pathway, thereby allowing the fungus to develop its disease in tomato (Solanum lycopersicum). SA-promoted disease development occurs through Nonexpressed Pathogen Related1. We also show that the JA signaling pathway required for tomato resistance against B. cinerea is mediated by the systemin elicitor. These data highlight a new strategy used by B. cinerea to overcome the plant's defense system and to spread within the host.<\/jats:p>","DOI":"10.1105\/tpc.111.083394","type":"journal-article","created":{"date-parts":[[2011,6,10]],"date-time":"2011-06-10T23:42:52Z","timestamp":1307749372000},"page":"2405-2421","source":"Crossref","is-referenced-by-count":375,"title":["<i>Botrytis cinerea<\/i>\n                    Manipulates the Antagonistic Effects between Immune Pathways to Promote Disease Development in Tomato\n\u00a0\n\u00a0"],"prefix":"10.1093","volume":"23","author":[{"given":"Mohamed","family":"El Oirdi","sequence":"first","affiliation":[{"name":"Centre de Recherche en Am\u00e9lioration V\u00e9g\u00e9tale, D\u00e9partement de Biologie, Facult\u00e9 des Sciences, Universit\u00e9 de Sherbrooke, Sherbrooke, Quebec J1K 2R1, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taha Abd","family":"El Rahman","sequence":"additional","affiliation":[{"name":"Centre de Recherche en Am\u00e9lioration V\u00e9g\u00e9tale, D\u00e9partement de Biologie, Facult\u00e9 des Sciences, Universit\u00e9 de Sherbrooke, Sherbrooke, Quebec J1K 2R1, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luciano","family":"Rigano","sequence":"additional","affiliation":[{"name":"Instituto de Ciencia y Tecnolog\u00eda Dr. Cesar Milstein, Fundaci\u00f3n Pablo Cassar\u00e1-Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas (CONICET), Saladillo 2468-C1440FFX, Ciudad de Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdelbasset","family":"El Hadrami","sequence":"additional","affiliation":[{"name":"Department of Plant Science, University of Manitoba, Winnipeg, Manitoba R3T 2N2, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Cecilia","family":"Rodriguez","sequence":"additional","affiliation":[{"name":"Departamento de Biodiversidad y Biolog\u00eda Experimental and Centro de Investigaciones en Hidratos de Carbono (CONICET), Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, C1428EGA Ciudad de Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fouad","family":"Daayf","sequence":"additional","affiliation":[{"name":"Department of Plant Science, University of Manitoba, Winnipeg, Manitoba R3T 2N2, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrian","family":"Vojnov","sequence":"additional","affiliation":[{"name":"Instituto de Ciencia y Tecnolog\u00eda Dr. Cesar Milstein, Fundaci\u00f3n Pablo Cassar\u00e1-Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas (CONICET), Saladillo 2468-C1440FFX, Ciudad de Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamal","family":"Bouarab","sequence":"additional","affiliation":[{"name":"Centre de Recherche en Am\u00e9lioration V\u00e9g\u00e9tale, D\u00e9partement de Biologie, Facult\u00e9 des Sciences, Universit\u00e9 de Sherbrooke, Sherbrooke, Quebec J1K 2R1, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2011,6,1]]},"reference":[{"key":"2021040622140142000_b1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.femsle.2005.02.025","article-title":"AvrPtoB: A bacterial type III effector that both elicits and suppresses programmed cell death associated with plant immunity","volume":"245","author":"Abramovitch","year":"2005","journal-title":"FEMS Microbiol. Lett."},{"key":"2021040622140142000_b2","doi-asserted-by":"crossref","first-page":"1964","DOI":"10.1105\/tpc.108.059477","article-title":"Tomato protein kinase 1b mediates signaling of plant responses to necrotrophic fungi and insect herbivory","volume":"20","author":"AbuQamar","year":"2008","journal-title":"Plant Cell"},{"key":"2021040622140142000_b3","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1111\/j.1365-313X.2006.02849.x","article-title":"Expression profiling and mutant analysis reveals complex regulatory networks involved in Arabidopsis response to Botrytis infection","volume":"48","author":"AbuQamar","year":"2006","journal-title":"Plant J."},{"key":"2021040622140142000_b4","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1105\/tpc.106.048041","article-title":"ABA is an essential signal for plant resistance to pathogens affecting JA biosynthesis and the activation of defenses in Arabidopsis","volume":"19","author":"Adie","year":"2007","journal-title":"Plant Cell"},{"key":"2021040622140142000_b5","first-page":"911","article-title":"A key enzyme for flavin synthesis is required for nitric oxide and reactive oxygen species production in disease resistance","volume":"62","author":"Asai","year":"2010","journal-title":"Plant J."},{"key":"2021040622140142000_b6","doi-asserted-by":"crossref","first-page":"1863","DOI":"10.1104\/pp.107.099226","article-title":"Resistance to Botrytis cinerea in sitiens, an abscisic acid-deficient tomato mutant, involves timely production of hydrogen peroxide and cell wall modifications in the epidermis","volume":"144","author":"Asselbergh","year":"2007","journal-title":"Plant Physiol."},{"key":"2021040622140142000_b7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1055\/s-2005-872705","article-title":"Fine-tuning plant defence signalling: Salicylate versus jasmonate","volume":"8","author":"Beckers","year":"2006","journal-title":"Plant Biol. (Stuttg.)"},{"key":"2021040622140142000_b8","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1146\/annurev.phyto.45.062806.094427","article-title":"Elicitors, effectors, and R genes: The new paradigm and a lifetime supply of questions","volume":"45","author":"Bent","year":"2007","journal-title":"Annu. Rev. Phytopathol."},{"key":"2021040622140142000_b9","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1038\/nature00950","article-title":"A saponin-detoxifying enzyme mediates suppression of plant defences","volume":"418","author":"Bouarab","year":"2002","journal-title":"Nature"},{"key":"2021040622140142000_b10","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1046\/j.1365-313x.2000.00778.x","article-title":"Salicylic acid is not required for Cf-2- and Cf-9-dependent resistance of tomato to Cladosporium fulvum","volume":"23","author":"Brading","year":"2000","journal-title":"Plant J."},{"key":"2021040622140142000_b11","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1111\/j.1364-3703.2005.00311.x","article-title":"The Pseudomonas syringae phytotoxin coronatine promotes virulence by overcoming salicylic acid-dependent defences in Arabidopsis thaliana","volume":"6","author":"Brooks","year":"2005","journal-title":"Mol. Plant Pathol."},{"key":"2021040622140142000_b12","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1016\/j.cell.2006.02.008","article-title":"Host-microbe interactions: Shaping the evolution of the plant immune response","volume":"124","author":"Chisholm","year":"2006","journal-title":"Cell"},{"key":"2021040622140142000_b13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1574-6968.2007.00930.x","article-title":"Botrytis cinerea virulence factors: New insights into a necrotrophic and polyphageous pathogen","volume":"277","author":"Choquer","year":"2007","journal-title":"FEMS Microbiol. Lett."},{"key":"2021040622140142000_b14","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1126\/science.1164627","article-title":"Glucosinolate metabolites required for an Arabidopsis innate immune response","volume":"323","author":"Clay","year":"2009","journal-title":"Science"},{"key":"2021040622140142000_b15","first-page":"181","article-title":"The Biology of Botrytis","author":"Coley-Smith","year":"1980"},{"key":"2021040622140142000_b16","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1023\/A:1005986004615","article-title":"Prosystemin from potato, black nightshade, and bell pepper: Primary structure and biological activity of predicted systemin polypeptides","volume":"36","author":"Constabel","year":"1998","journal-title":"Plant Mol. Biol."},{"key":"2021040622140142000_b17","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.1073\/pnas.0409450102","article-title":"Pseudomonas syringae manipulates systemic plant defenses against pathogens and herbivores","volume":"102","author":"Cui","year":"2005","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2021040622140142000_b18","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1104\/pp.110.158972","article-title":"Abscisic acid deficiency causes changes in cuticle permeability and pectin composition that influence tomato resistance to Botrytis cinerea","volume":"154","author":"Curvers","year":"2010","journal-title":"Plant Physiol."},{"key":"2021040622140142000_b19","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1104\/pp.113.3.719","article-title":"Evidence of phytoalexins in cucumber leaves infected with powdery mildew following treatment with leaf extracts of Reynoutria sachalinensis","volume":"113","author":"Daayf","year":"1997","journal-title":"Plant Physiol."},{"key":"2021040622140142000_b20","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.1038\/sj.emboj.7601575","article-title":"Pseudomonas syringae pv. tomato hijacks the Arabidopsis abscisic acid signalling pathway to cause disease","volume":"26","author":"de Torres-Zabala","year":"2007","journal-title":"EMBO J."},{"key":"2021040622140142000_b21","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1104\/pp.108.4.1741","article-title":"Salicylic acid inhibits synthesis of proteinase inhibitors in tomato leaves induced by systemin and jasmonic acid","volume":"108","author":"Doares","year":"1995","journal-title":"Plant Physiol."},{"key":"2021040622140142000_b22","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/S0008-6215(00)80860-5","article-title":"Structure of the extracellular [beta]-d-glucan from Botrytis cinerea","volume":"93","author":"Dubourdieu","year":"1981","journal-title":"Carbohydr. Res."},{"key":"2021040622140142000_b23","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1146\/annurev.phyto.42.040803.140421","article-title":"Systemic acquired resistance","volume":"42","author":"Durrant","year":"2004","journal-title":"Annu. Rev. Phytopathol."},{"key":"2021040622140142000_b24","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1080\/07060660909507614","article-title":"Priming canola resistance to blackleg with weakly aggressive isolates leads to an activation of hydroxycinnamates","volume":"31","author":"El Hadrami","year":"2009","journal-title":"Can. J. Plant Pathol."},{"key":"2021040622140142000_b25","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1111\/j.1469-8137.2007.02086.x","article-title":"Plant signalling components EDS1 and SGT1 enhance disease caused by the necrotrophic pathogen Botrytis cinerea","volume":"175","author":"El Oirdi","year":"2007","journal-title":"New Phytol."},{"key":"2021040622140142000_b26","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1111\/j.1462-2920.2009.02063.x","article-title":"The nature of tobacco resistance against Botrytis cinerea depends on the infection structures of the pathogen","volume":"12","author":"El Oirdi","year":"2010","journal-title":"Environ. Microbiol."},{"key":"2021040622140142000_b27","doi-asserted-by":"crossref","first-page":"129","DOI":"10.2307\/3869566","article-title":"Octadecanoid precursors of jasmonic acid activate the synthesis of wound-inducible proteinase inhibitors","volume":"4","author":"Farmer","year":"1992","journal-title":"Plant Cell"},{"key":"2021040622140142000_b28","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1046\/j.1365-313X.2003.01794.x","article-title":"Arabidopsis local resistance to Botrytis cinerea involves salicylic acid and camalexin and requires EDS4 and PAD2, but not SID2, EDS5 or PAD4","volume":"35","author":"Ferrari","year":"2003","journal-title":"Plant J."},{"key":"2021040622140142000_b29","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1146\/annurev.phyto.43.040204.135923","article-title":"Contrasting mechanisms of defense against biotrophic and necrotrophic pathogens","volume":"43","author":"Glazebrook","year":"2005","journal-title":"Annu. Rev. Phytopathol."},{"key":"2021040622140142000_b30","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S0378-1119(96)00322-8","article-title":"Rhizobium meliloti exopolysaccharides: Synthesis and symbiotic function","volume":"179","author":"Gonz\u00e1lez","year":"1996","journal-title":"Gene"},{"key":"2021040622140142000_b31","doi-asserted-by":"crossref","first-page":"3400","DOI":"10.3390\/ijms10083400","article-title":"Plant antimicrobial agents and their effects on plant and human pathogens","volume":"10","author":"Gonz\u00e1lez-Lamothe","year":"2009","journal-title":"Int. J. Mol. Sci."},{"key":"2021040622140142000_b32","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1023\/A:1013323222095","article-title":"Infection of Arabidopsis with a necrotrophic pathogen, Botrytis cinerea, elicits various defense responses but does not induce systemic acquired resistance (SAR)","volume":"48","author":"Govrin","year":"2002","journal-title":"Plant Mol. Biol."},{"key":"2021040622140142000_b33","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/j.pbi.2006.05.013","article-title":"Systemic immunity","volume":"9","author":"Grant","year":"2006","journal-title":"Curr. Opin. Plant Biol."},{"key":"2021040622140142000_b34","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1126\/science.1173771","article-title":"Hormone (Dis)harmony moulds plant health and disease","volume":"324","author":"Grant","year":"2009","journal-title":"Science"},{"key":"2021040622140142000_b35","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/j.pbi.2010.04.003","article-title":"Bacterial virulence effectors and their activities","volume":"13","author":"Hann","year":"2010","journal-title":"Curr. Opin. Plant Biol."},{"key":"2021040622140142000_b36","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1105\/tpc.109.071449","article-title":"Jasmonate and ppHsystemin regulate key malonylation steps in the biosynthesis of 17-hydroxygeranyllinalool diterpene glycosides, an abundant and effective direct defense against herbivores in Nicotiana attenuata","volume":"22","author":"Heiling","year":"2010","journal-title":"Plant Cell"},{"key":"2021040622140142000_b37","doi-asserted-by":"crossref","first-page":"5460","DOI":"10.1128\/JB.186.16.5460-5472.2004","article-title":"The LuxR homolog ExpR, in combination with the sin quorum sensing system, plays a central role in Sinorhizobium meliloti gene expression","volume":"186","author":"Hoang","year":"2004","journal-title":"J. Bacteriol."},{"key":"2021040622140142000_b38","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1126\/science.1120131","article-title":"A bacterial inhibitor of host programmed cell death defenses is an E3 ubiquitin ligase","volume":"311","author":"Janjusevic","year":"2006","journal-title":"Science"},{"key":"2021040622140142000_b39","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1038\/nature05286","article-title":"The plant immune system","volume":"444","author":"Jones","year":"2006","journal-title":"Nature"},{"key":"2021040622140142000_b40","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1038\/nrmicro1705","article-title":"How rhizobial symbionts invade plants: The Sinorhizobium-Medicago model","volume":"5","author":"Jones","year":"2007","journal-title":"Nat. Rev. Microbiol."},{"key":"2021040622140142000_b41","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1073\/pnas.0709338105","article-title":"Differential response of the plant Medicago truncatula to its symbiont Sinorhizobium meliloti or an exopolysaccharide-deficient mutant","volume":"105","author":"Jones","year":"2008","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2021040622140142000_b42","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1094\/MPMI-20-4-0335","article-title":"ABA is required for Leptosphaeria maculans resistance via ABI1- and ABI4-dependent signaling","volume":"20","author":"Kaliff","year":"2007","journal-title":"Mol. Plant Microbe Interact."},{"key":"2021040622140142000_b43","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1104\/pp.124.3.1027","article-title":"Linear beta -1,3 glucans are elicitors of defense responses in tobacco","volume":"124","author":"Klarzynski","year":"2000","journal-title":"Plant Physiol."},{"key":"2021040622140142000_b44","doi-asserted-by":"crossref","first-page":"1358","DOI":"10.1104\/pp.108.121392","article-title":"Kinetics of salicylate-mediated suppression of jasmonate signaling reveal a role for redox modulation","volume":"147","author":"Koornneef","year":"2008","journal-title":"Plant Physiol."},{"key":"2021040622140142000_b45","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1104\/pp.107.112029","article-title":"Cross talk in defense signaling","volume":"146","author":"Koornneef","year":"2008","journal-title":"Plant Physiol."},{"key":"2021040622140142000_b46","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1094\/MPMI-19-0789","article-title":"The Arabidopsis thaliana JASMONATE INSENSITIVE 1 gene is required for suppression of salicylic acid-dependent defenses during infection by Pseudomonas syringae","volume":"19","author":"Laurie-Berry","year":"2006","journal-title":"Mol. Plant Microbe Interact."},{"key":"2021040622140142000_b47","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.1104\/pp.108.133926","article-title":"Ethylene modulates the role of NONEXPRESSOR OF PATHOGENESIS-RELATED GENES1 in cross talk between salicylate and jasmonate signaling","volume":"149","author":"Leon-Reyes","year":"2009","journal-title":"Plant Physiol."},{"key":"2021040622140142000_b48","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1007\/s00425-010-1265-z","article-title":"Salicylate-mediated suppression of jasmonate-responsive gene expression in Arabidopsis is targeted downstream of the jasmonate biosynthesis pathway","volume":"232","author":"Leon-Reyes","year":"2010","journal-title":"Planta"},{"key":"2021040622140142000_b49","doi-asserted-by":"crossref","first-page":"1646","DOI":"10.1105\/tpc.012237","article-title":"The tomato suppressor of prosystemin-mediated responses2 gene encodes a fatty acid desaturase required for the biosynthesis of jasmonic acid and the production of a systemic wound signal for defense gene expression","volume":"15","author":"Li","year":"2003","journal-title":"Plant Cell"},{"key":"2021040622140142000_b50","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1007\/s11248-004-2375-9","article-title":"Transgenic tomato plants expressing the Arabidopsis NPR1gene display enhanced resistance to a spectrum of fungal and bacterial diseases","volume":"13","author":"Lin","year":"2004","journal-title":"Transgenic Res."},{"key":"2021040622140142000_b51","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1046\/j.1365-313X.2002.01394.x","article-title":"Virus-induced gene silencing in tomato","volume":"31","author":"Liu","year":"2002","journal-title":"Plant J."},{"key":"2021040622140142000_b52","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/j.pbi.2007.08.008","article-title":"Salicylic acid in plant defence\u2013The players and protagonists","volume":"10","author":"Loake","year":"2007","journal-title":"Curr. Opin. Plant Biol."},{"key":"2021040622140142000_b53","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1104\/pp.105.072348","article-title":"The outcomes of concentration-specific interactions between salicylate and jasmonate signaling include synergy, antagonism, and oxidative stress leading to cell death","volume":"140","author":"Mur","year":"2006","journal-title":"Plant Physiol."},{"key":"2021040622140142000_b54","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1016\/j.cub.2008.03.060","article-title":"DELLAs control plant immune responses by modulating the balance of jasmonic acid and salicylic acid signaling","volume":"18","author":"Navarro","year":"2008","journal-title":"Curr. Biol."},{"key":"2021040622140142000_b55","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1126\/science.1126088","article-title":"A Plant miRNA contributes to antibacterial resistance by repressing auxin signaling","volume":"312","author":"Navarro","year":"2006","journal-title":"Science"},{"key":"2021040622140142000_b56","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1111\/j.1365-313X.2007.03039.x","article-title":"SA-inducible Arabidopsis glutaredoxin interacts with TGA factors and suppresses JA-responsive PDF1.2 transcription","volume":"50","author":"Ndamukong","year":"2007","journal-title":"Plant J."},{"key":"2021040622140142000_b57","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1007\/BF00196971","article-title":"Plant defense and delayed infection of alfalfa pseudonodules induced by an exopolysaccharide (EPS-I)-deficient Rhizobium meliloti mutant","volume":"190","author":"Niehaus","year":"1993","journal-title":"Planta"},{"key":"2021040622140142000_b58","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1126\/science.1129523","article-title":"A bacterial virulence protein suppresses host innate immunity to cause plant disease","volume":"313","author":"Nomura","year":"2006","journal-title":"Science"},{"key":"2021040622140142000_b59","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1104\/pp.103.030379","article-title":"Multiple hormones act sequentially to mediate a susceptible tomato pathogen defense response","volume":"133","author":"O'Donnell","year":"2003","journal-title":"Plant Physiol."},{"key":"2021040622140142000_b60","doi-asserted-by":"crossref","first-page":"1422","DOI":"10.1104\/pp.109.138669","article-title":"Isolation and characterization of hydroxyproline-rich glycopeptide signals in black nightshade leaves","volume":"150","author":"Pearce","year":"2009","journal-title":"Plant Physiol."},{"key":"2021040622140142000_b61","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.pbi.2004.05.006","article-title":"NPR1: The spider in the web of induced resistance signaling pathways","volume":"7","author":"Pieterse","year":"2004","journal-title":"Curr. Opin. Plant Biol."},{"key":"2021040622140142000_b62","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1046\/j.0960-7412.2000.00942.x","article-title":"Technical advance: Tobacco rattle virus as a vector for analysis of gene function by silencing","volume":"25","author":"Ratcliff","year":"2001","journal-title":"Plant J."},{"key":"2021040622140142000_b63","doi-asserted-by":"crossref","first-page":"2077","DOI":"10.1105\/tpc.106.047944","article-title":"Bacterial cyclic {beta}-(1,2)-glucan acts in systemic suppression of plant immune responses","volume":"19","author":"Rigano","year":"2007","journal-title":"Plant Cell"},{"key":"2021040622140142000_b64","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.pbi.2007.06.003","article-title":"Pathological hormone imbalances","volume":"10","author":"Robert-Seilaniantz","year":"2007","journal-title":"Curr. Opin. Plant Biol."},{"key":"2021040622140142000_b65","doi-asserted-by":"crossref","first-page":"e1000861","DOI":"10.1371\/journal.ppat.1000861","article-title":"Deficiencies in jasmonate-mediated plant defense reveal quantitative variation in Botrytis cinerea pathogenesis","volume":"6","author":"Rowe","year":"2010","journal-title":"PLoS Pathog."},{"key":"2021040622140142000_b66","doi-asserted-by":"crossref","first-page":"14577","DOI":"10.1073\/pnas.1934788100","article-title":"Systemins: A functionally defined family of peptide signals that regulate defensive genes in Solanaceae species","volume":"100","author":"Ryan","year":"2003","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2021040622140142000_b67","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/j.phytochem.2005.11.017","article-title":"Simultaneous quantitative LC-ESI-MS\/MS analyses of salicylic acid and jasmonic acid in crude extracts of Cucumis sativus under biotic stress","volume":"67","author":"Segarra","year":"2006","journal-title":"Phytochemistry"},{"key":"2021040622140142000_b68","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/j.pbi.2009.05.011","article-title":"Plants under attack: Systemic signals in defence","volume":"12","author":"Shah","year":"2009","journal-title":"Curr. Opin. Plant Biol."},{"key":"2021040622140142000_b69","doi-asserted-by":"crossref","first-page":"3167","DOI":"10.1099\/mic.0.29112-0","article-title":"Rhizobia and plant-pathogenic bacteria: Common infection weapons","volume":"152","author":"Soto","year":"2006","journal-title":"Microbiology"},{"key":"2021040622140142000_b70","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/j.chom.2008.05.009","article-title":"Making sense of hormone crosstalk during plant immune responses","volume":"3","author":"Spoel","year":"2008","journal-title":"Cell Host Microbe"},{"key":"2021040622140142000_b71","doi-asserted-by":"crossref","first-page":"18842","DOI":"10.1073\/pnas.0708139104","article-title":"Regulation of tradeoffs between plant defenses against pathogens with different lifestyles","volume":"104","author":"Spoel","year":"2007","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2021040622140142000_b72","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1105\/tpc.009159","article-title":"NPR1 modulates cross-talk between salicylate- and jasmonate-dependent defense pathways through a novel function in the cytosol","volume":"15","author":"Spoel","year":"2003","journal-title":"Plant Cell"},{"key":"2021040622140142000_b73","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/0008-6215(94)00245-B","article-title":"Structural properties of native and sonicated cinerean, a [beta]-(1 \u2192 3)(1 \u2192 6)\u2013glucan produced by Botrytis cinerea","volume":"266","author":"Stahmann","year":"1995","journal-title":"Carbohydr. Res."},{"key":"2021040622140142000_b74","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1111\/j.1365-313X.2009.03794.x","article-title":"The ABC transporter BcatrB from Botrytis cinerea exports camalexin and is a virulence factor on Arabidopsis thaliana","volume":"58","author":"Stefanato","year":"2009","journal-title":"Plant J."},{"key":"2021040622140142000_b75","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1146\/annurev.arplant.55.031903.141753","article-title":"Molecular mechanism of gibberellins signaling in plants","volume":"55","author":"Sun","year":"2004","journal-title":"Annu. Rev. Plant Biol."},{"key":"2021040622140142000_b76","doi-asserted-by":"crossref","first-page":"1562","DOI":"10.1104\/pp.109.152173","article-title":"Arabidopsis auxin mutants are compromised in systemic acquired resistance and exhibit aberrant accumulation of various indolic compounds","volume":"152","author":"Truman","year":"2010","journal-title":"Plant Physiol."},{"key":"2021040622140142000_b77","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1146\/annurev.phyto.44.070505.143425","article-title":"Significance of inducible defense-related proteins in infected plants","volume":"44","author":"van Loon","year":"2006","journal-title":"Annu. Rev. Phytopathol."},{"key":"2021040622140142000_b78","doi-asserted-by":"crossref","first-page":"8711","DOI":"10.1073\/pnas.130425197","article-title":"Enhancement of induced disease resistance by simultaneous activation of salicylate- and jasmonate-dependent defense pathways in Arabidopsis thaliana","volume":"97","author":"van Wees","year":"2000","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2021040622140142000_b79","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1104\/pp.110.161570","article-title":"Plant immunity: It's the hormones talking, but what do they say?","volume":"154","author":"Verhage","year":"2010","journal-title":"Plant Physiol."},{"key":"2021040622140142000_b80","doi-asserted-by":"crossref","first-page":"1784","DOI":"10.1016\/j.cub.2007.09.025","article-title":"Salicylic acid inhibits pathogen growth in plants through repression of the auxin signaling pathway","volume":"17","author":"Wang","year":"2007","journal-title":"Curr. Biol."},{"key":"2021040622140142000_b81","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1111\/j.1467-7652.2007.00243.x","article-title":"Functional analysis of rice NPR1-like genes reveals that OsNPR1\/NH1 is the rice orthologue conferring disease resistance with enhanced herbivore susceptibility","volume":"5","author":"Yuan","year":"2007","journal-title":"Plant Biotechnol. J."},{"key":"2021040622140142000_b82","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1104\/pp.105.074542","article-title":"Xanthan induces plant susceptibility by suppressing callose deposition","volume":"141","author":"Yun","year":"2006","journal-title":"Plant Physiol."},{"key":"2021040622140142000_b83","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1104\/pp.106.090035","article-title":"Silverleaf whitefly induces salicylic acid defenses and suppresses effectual jasmonic acid defenses","volume":"143","author":"Zarate","year":"2007","journal-title":"Plant Physiol."},{"key":"2021040622140142000_b84","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/j.pbi.2009.06.003","article-title":"Early molecular events in PAMP-triggered immunity","volume":"12","author":"Zipfel","year":"2009","journal-title":"Curr. Opin. Plant Biol."}],"container-title":["The Plant Cell"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/plcell\/article-pdf\/23\/6\/2405\/36935964\/plcell_v23_6_2405.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/plcell\/article-pdf\/23\/6\/2405\/36935964\/plcell_v23_6_2405.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,6]],"date-time":"2021-04-06T21:28:30Z","timestamp":1617744510000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/plcell\/article\/23\/6\/2405\/6101010"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,6,1]]},"references-count":84,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2011,6,1]]},"published-print":{"date-parts":[[2011,6,1]]}},"URL":"https:\/\/doi.org\/10.1105\/tpc.111.083394","relation":{},"ISSN":["1532-298X","1040-4651"],"issn-type":[{"value":"1532-298X","type":"electronic"},{"value":"1040-4651","type":"print"}],"subject":[],"published-other":{"date-parts":[[2011,6,1]]},"published":{"date-parts":[[2011,6,1]]}}}