{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T22:22:02Z","timestamp":1792102922733,"version":"4.4.0"},"reference-count":71,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2013,3,1]],"date-time":"2013-03-01T00:00:00Z","timestamp":1362096000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,4,24]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Pathogen-associated molecular pattern (PAMP)-trigged immunity (PTI) is the first defensive line of plant innate immunity and is mediated by pattern recognition receptors. Here, we show that a mutation in BR-SIGNALING KINASE1 (BSK1), a substrate of the brassinosteroid (BR) receptor BRASSINOSTEROID INSENSITIVE1, suppressed the powdery mildew resistance caused by a mutation in ENHANCED DISEASE RESISTANCE2, which negatively regulates powdery mildew resistance and programmed cell death, in Arabidopsis thaliana. A loss-of-function bsk1 mutant displayed enhanced susceptibility to virulent and avirulent pathogens, including Golovinomyces cichoracearum, Pseudomonas syringae, and Hyaloperonospora arabidopsidis. The bsk1 mutant also accumulated lower levels of salicylic acid upon infection with G. cichoracearum and P. syringae. BSK1 belongs to a receptor-like cytoplasmic kinase family and displays kinase activity in vitro; this kinase activity is required for its function. BSK1 physically associates with the PAMP receptor FLAGELLIN SENSING2 and is required for a subset of flg22-induced responses, including the reactive oxygen burst, but not for mitogen-activated protein kinase activation. Our data demonstrate that BSK1 is involved in positive regulation of PTI. Together with previous findings, our work indicates that BSK1 represents a key component directly involved in both BR signaling and plant immunity.<\/jats:p>","DOI":"10.1105\/tpc.112.107904","type":"journal-article","created":{"date-parts":[[2013,3,27]],"date-time":"2013-03-27T00:38:51Z","timestamp":1364344731000},"page":"1143-1157","source":"Crossref","is-referenced-by-count":241,"title":["BR-SIGNALING KINASE1 Physically Associates with FLAGELLIN SENSING2 and Regulates Plant Innate Immunity in\n                    <i>Arabidopsis<\/i>\n                    \u00a0"],"prefix":"10.1093","volume":"25","author":[{"given":"Hua","family":"Shi","sequence":"first","affiliation":[{"name":"State Key Laboratory of Plant Cell and Chromosome Engineering, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China"},{"name":"University of Chinese Academy of Sciences, Beijing 100049, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiujing","family":"Shen","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Plant Cell and Chromosome Engineering, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China"},{"name":"University of Chinese Academy of Sciences, Beijing 100049, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiping","family":"Qi","sequence":"additional","affiliation":[{"name":"Department of Plant Biology, Microbial and Plant Genomics Institute, University of Minnesota, St. Paul, Minnesota 55108"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haojie","family":"Yan","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Plant Cell and Chromosome Engineering, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China"},{"name":"University of Chinese Academy of Sciences, Beijing 100049, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haozhen","family":"Nie","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Plant Cell and Chromosome Engineering, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China"},{"name":"University of Chinese Academy of Sciences, Beijing 100049, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongfang","family":"Chen","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Plant Cell and Chromosome Engineering, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Zhao","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Plant Cell and Chromosome Engineering, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fumiaki","family":"Katagiri","sequence":"additional","affiliation":[{"name":"Department of Plant Biology, Microbial and Plant Genomics Institute, University of Minnesota, St. Paul, Minnesota 55108"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dingzhong","family":"Tang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Plant Cell and Chromosome Engineering, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2013,3,26]]},"reference":[{"key":"2021040707181898800_b1","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1046\/j.1365-313X.1996.09030341.x","article-title":"Genetic characterization of five powdery mildew disease resistance loci in Arabidopsis thaliana","volume":"9","author":"Adam","year":"1996","journal-title":"Plant J."},{"key":"2021040707181898800_b2","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1073\/pnas.1109921108","article-title":"Brassinosteroids inhibit pathogen-associated molecular pattern-triggered immune signaling independent of the receptor kinase BAK1","volume":"109","author":"Albrecht","year":"2012","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2021040707181898800_b3","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1104\/pp.123.1.93","article-title":"Characterization of brassinazole, a triazole-type brassinosteroid biosynthesis inhibitor","volume":"123","author":"Asami","year":"2000","journal-title":"Plant Physiol."},{"key":"2021040707181898800_b4","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1073\/pnas.1112840108","article-title":"Brassinosteroids modulate the efficiency of plant immune responses to microbe-associated molecular patterns","volume":"109","author":"Belkhadir","year":"2012","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2021040707181898800_b5","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1146\/annurev.phyto.45.062806.094427","article-title":"Elicitors, effectors, and R genes: The new paradigm and a lifetime supply of questions","volume":"45","author":"Bent","year":"2007","journal-title":"Annu. Rev. Phytopathol."},{"key":"2021040707181898800_b6","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1002\/(SICI)1521-1878(199911)21:11<932::AID-BIES5>3.0.CO;2-N","article-title":"The tetratricopeptide repeat: A structural motif mediating protein-protein interactions","volume":"21","author":"Blatch","year":"1999","journal-title":"Bioessays"},{"key":"2021040707181898800_b7","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1038\/nature05999","article-title":"A flagellin-induced complex of the receptor FLS2 and BAK1 initiates plant defence","volume":"448","author":"Chinchilla","year":"2007","journal-title":"Nature"},{"key":"2021040707181898800_b8","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1016\/j.cell.2006.02.008","article-title":"Host-microbe interactions: Shaping the evolution of the plant immune response","volume":"124","author":"Chisholm","year":"2006","journal-title":"Cell"},{"key":"2021040707181898800_b9","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1046\/j.1365-313x.1998.00343.x","article-title":"Floral dip: A simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana","volume":"16","author":"Clough","year":"1998","journal-title":"Plant J."},{"key":"2021040707181898800_b10","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1038\/ng1806","article-title":"Conserved requirement for a plant host cell protein in powdery mildew pathogenesis","volume":"38","author":"Consonni","year":"2006","journal-title":"Nat. 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Plant Biol."},{"key":"2021040707181898800_b14","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1105\/tpc.10.6.947","article-title":"An Arabidopsis mutant with enhanced resistance to powdery mildew","volume":"10","author":"Frye","year":"1998","journal-title":"Plant Cell"},{"key":"2021040707181898800_b15","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1073\/pnas.98.1.373","article-title":"Negative regulation of defense responses in plants by a conserved MAPKK kinase","volume":"98","author":"Frye","year":"2001","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2021040707181898800_b16","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1007\/BF00028910","article-title":"A versatile binary vector system with a T-DNA organisational structure conducive to efficient integration of cloned DNA into the plant genome","volume":"20","author":"Gleave","year":"1992","journal-title":"Plant Mol. Biol."},{"key":"2021040707181898800_b17","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1016\/S1097-2765(00)80265-8","article-title":"FLS2: An LRR receptor-like kinase involved in the perception of the bacterial elicitor flagellin in Arabidopsis","volume":"5","author":"G\u00f3mez-G\u00f3mez","year":"2000","journal-title":"Mol. Cell"},{"key":"2021040707181898800_b18","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1111\/j.1365-313X.2009.03995.x","article-title":"An F-box gene, CPR30, functions as a negative regulator of the defense response in Arabidopsis","volume":"60","author":"Gou","year":"2009","journal-title":"Plant J."},{"key":"2021040707181898800_b19","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1038\/35074106","article-title":"The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5","volume":"410","author":"Hayashi","year":"2001","journal-title":"Nature"},{"key":"2021040707181898800_b20","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1016\/j.cub.2007.05.036","article-title":"BAK1 and BKK1 regulate brassinosteroid-dependent growth and brassinosteroid-independent cell-death pathways","volume":"17","author":"He","year":"2007","journal-title":"Curr. 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Biol."},{"key":"2021040707181898800_b23","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1126\/science.1211641","article-title":"Arabidopsis EDS1 connects pathogen effector recognition to cell compartment-specific immune responses","volume":"334","author":"Heidrich","year":"2011","journal-title":"Science"},{"key":"2021040707181898800_b24","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/0092-8674(90)90746-2","article-title":"Snap helix with knob and hole: Essential repeats in S. pombe nuclear protein nuc2+","volume":"60","author":"Hirano","year":"1990","journal-title":"Cell"},{"key":"2021040707181898800_b25","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.chom.2011.02.002","article-title":"Activation of plant nod-like receptors: How indirect can it be?","volume":"9","author":"Innes","year":"2011","journal-title":"Cell Host Microbe"},{"key":"2021040707181898800_b26","doi-asserted-by":"crossref","first-page":"13583","DOI":"10.1073\/pnas.96.23.13583","article-title":"Arabidopsis thaliana PAD4 encodes a lipase-like gene that is important for salicylic acid signaling","volume":"96","author":"Jirage","year":"1999","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2021040707181898800_b27","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1038\/nature05286","article-title":"The plant immune system","volume":"444","author":"Jones","year":"2006","journal-title":"Nature"},{"key":"2021040707181898800_b28","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1105\/tpc.105.039412","article-title":"The Arabidopsis SOMATIC EMBRYOGENESIS RECEPTOR-LIKE KINASE1 protein complex includes BRASSINOSTEROID-INSENSITIVE1","volume":"18","author":"Karlova","year":"2006","journal-title":"Plant Cell"},{"key":"2021040707181898800_b29","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1038\/ncb1970","article-title":"Brassinosteroid signal transduction from cell-surface receptor kinases to nuclear transcription factors","volume":"11","author":"Kim","year":"2009","journal-title":"Nat. Cell Biol."},{"key":"2021040707181898800_b30","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1126\/science.272.5260.398","article-title":"A role for brassinosteroids in light-dependent development of Arabidopsis","volume":"272","author":"Li","year":"1996","journal-title":"Science"},{"key":"2021040707181898800_b31","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/S0092-8674(02)00812-7","article-title":"BAK1, an Arabidopsis LRR receptor-like protein kinase, interacts with BRI1 and modulates brassinosteroid signaling","volume":"110","author":"Li","year":"2002","journal-title":"Cell"},{"key":"2021040707181898800_b32","doi-asserted-by":"crossref","first-page":"e1001111","DOI":"10.1371\/journal.ppat.1001111","article-title":"SRFR1 negatively regulates plant NB-LRR resistance protein accumulation to prevent autoimmunity","volume":"6","author":"Li","year":"2010","journal-title":"PLoS Pathog."},{"key":"2021040707181898800_b33","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.chom.2011.01.010","article-title":"A receptor-like cytoplasmic kinase phosphorylates the host target RIN4, leading to the activation of a plant innate immune receptor","volume":"9","author":"Liu","year":"2011","journal-title":"Cell Host Microbe"},{"key":"2021040707181898800_b34","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1111\/j.1365-313X.2009.04109.x","article-title":"An efficient system to detect protein ubiquitination by agroinfiltration in Nicotiana benthamiana","volume":"61","author":"Liu","year":"2010","journal-title":"Plant J."},{"key":"2021040707181898800_b35","doi-asserted-by":"crossref","first-page":"2817","DOI":"10.1093\/molbev\/msq169","article-title":"Dramatic change in function and expression pattern of a gene duplicated by polyploidy created a paternal effect gene in the Brassicaceae","volume":"27","author":"Liu","year":"2010","journal-title":"Mol. Biol. Evol."},{"key":"2021040707181898800_b36","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1073\/pnas.0909705107","article-title":"A receptor-like cytoplasmic kinase, BIK1, associates with a flagellin receptor complex to initiate plant innate immunity","volume":"107","author":"Lu","year":"2010","journal-title":"Proc. Natl. Acad. Sci. 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Biosci. Bioeng."},{"key":"2021040707181898800_b42","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0092-8674(02)00814-0","article-title":"BRI1\/BAK1, a receptor kinase pair mediating brassinosteroid signaling","volume":"110","author":"Nam","year":"2002","journal-title":"Cell"},{"key":"2021040707181898800_b43","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.jgg.2011.03.001","article-title":"Suppression of edr2-mediated powdery mildew resistance, cell death and ethylene-induced senescence by mutations in ALD1 in Arabidopsis","volume":"38","author":"Nie","year":"2011","journal-title":"J. Genet. Genomics"},{"key":"2021040707181898800_b44","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.1104\/pp.111.192310","article-title":"SR1, a calmodulin-binding transcription factor, modulates plant defense and ethylene-induced senescence by directly regulating NDR1 and EIN3","volume":"158","author":"Nie","year":"2012","journal-title":"Plant Physiol."},{"key":"2021040707181898800_b45","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1126\/science.1086716","article-title":"Loss of a callose synthase results in salicylic acid-dependent disease resistance","volume":"301","author":"Nishimura","year":"2003","journal-title":"Science"},{"key":"2021040707181898800_b46","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1104\/pp.121.3.743","article-title":"Brassinosteroid-insensitive dwarf mutants of Arabidopsis accumulate brassinosteroids","volume":"121","author":"Noguchi","year":"1999","journal-title":"Plant Physiol."},{"key":"2021040707181898800_b47","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1111\/j.1365-313X.2011.04835.x","article-title":"HPR1, a component of the THO\/TREX complex, plays an important role in disease resistance and senescence in Arabidopsis","volume":"69","author":"Pan","year":"2012","journal-title":"Plant J."},{"key":"2021040707181898800_b48","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1111\/j.1364-3703.2010.00704.x","article-title":"Physical association of pattern-triggered immunity (PTI) and effector-triggered immunity (ETI) immune receptors in Arabidopsis","volume":"12","author":"Qi","year":"2011","journal-title":"Mol. Plant Pathol."},{"key":"2021040707181898800_b49","doi-asserted-by":"crossref","first-page":"2440","DOI":"10.1105\/tpc.111.084301","article-title":"The Arabidopsis leucine-rich repeat receptor-like kinases BAK1\/SERK3 and BKK1\/SERK4 are required for innate immunity to hemibiotrophic and biotrophic pathogens","volume":"23","author":"Roux","year":"2011","journal-title":"Plant Cell"},{"key":"2021040707181898800_b50","doi-asserted-by":"crossref","first-page":"9444","DOI":"10.1074\/jbc.M109.096842","article-title":"Rapid heteromerization and phosphorylation of ligand-activated plant transmembrane receptors and their associated kinase BAK1","volume":"285","author":"Schulze","year":"2010","journal-title":"J. Biol. 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