{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T12:45:00Z","timestamp":1791981900183,"version":"4.4.0"},"reference-count":39,"publisher":"International Union of Crystallography (IUCr)","issue":"5","license":[{"start":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T00:00:00Z","timestamp":1790294400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"},{"start":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T00:00:00Z","timestamp":1790294400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"}],"funder":[{"DOI":"10.13039\/501100002341","name":"Academy of Finland","doi-asserted-by":"publisher","award":["315596"],"award-info":[{"award-number":["315596"]}],"id":[{"id":"10.13039\/501100002341","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002341","name":"Academy of Finland","doi-asserted-by":"publisher","award":["356568"],"award-info":[{"award-number":["356568"]}],"id":[{"id":"10.13039\/501100002341","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100018693","name":"HORIZON EUROPE Framework Programme","doi-asserted-by":"publisher","award":["101129751"],"award-info":[{"award-number":["101129751"]}],"id":[{"id":"10.13039\/100018693","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["iucr.org","wiley.com","iucrj.org"],"crossmark-restriction":true},"short-container-title":["J Appl Crystallogr","J Appl Cryst"],"accepted":{"date-parts":[[2026,7,29]]},"published-print":{"date-parts":[[2026,10,1]]},"abstract":"<jats:p>\n                    Accurate quantification of water permeation across lipid membranes is challenging, with reported permeability values varying widely due to methodological differences and sample heterogeneity. Here, we show that time-resolved small-angle neutron scattering with rapid contrast variation enables direct non-invasive measurement of water permeation kinetics and membrane structure under iso-osmotic conditions. Our results indicate much faster water permeation in gel-phase bilayers than previously reported, likely due to improved structural control and the removal of multilamellar artefacts. Molecular-dynamics simulations agree in activation energies, though absolute permeabilities are higher\n                    <jats:italic>in silico<\/jats:italic>\n                    , highlighting methodological sensitivities. Our integrated approach offers new possibilities for future studies of diffusive solute transport across lipid membranes.\n                  <\/jats:p>","DOI":"10.1107\/s1600576726007788","type":"journal-article","created":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T17:14:56Z","timestamp":1787850896000},"page":"1550-1556","update-policy":"https:\/\/doi.org\/10.1107\/cm_01","source":"Crossref","is-referenced-by-count":0,"title":["Determination of water permeability in stress-free lipid membranes through time-resolved small-angle neutron scattering"],"prefix":"10.1107","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0329-5305","authenticated-orcid":true,"given":"Moritz P. K.","family":"Frewein","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ursula","family":"Perez-Salas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O. H. Samuli","family":"Ollila","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1967-1536","authenticated-orcid":true,"given":"Georg","family":"Pabst","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4674-7591","authenticated-orcid":true,"given":"Lionel","family":"Porcar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"329","published-online":{"date-parts":[[2026,9,25]]},"reference":[{"key":"ge5184_bb1","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1007\/s13538-022-01071-1","volume":"52","author":"Camilo","year":"2022","journal-title":"Braz. J. 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K. Frewein\n                      et al.","order":0,"name":"copyright","label":"Copyright","explanation":{"URL":"https:\/\/journals.iucr.org\/services\/copyrightpolicy.html"},"group":{"name":"copyright_and_licencing","label":"Copyright and licencing"}},{"value":"Creative Commons Attribution (CC-BY)","order":1,"name":"license","label":"Licence","explanation":{"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/legalcode"},"group":{"name":"copyright_and_licencing","label":"Copyright and licencing"}}]}}