{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,1,11]],"date-time":"2025-01-11T15:10:25Z","timestamp":1736608225754,"version":"3.32.0"},"reference-count":32,"publisher":"International Union of Crystallography (IUCr)","issue":"9","license":[{"start":{"date-parts":[[2010,8,21]],"date-time":"2010-08-21T00:00:00Z","timestamp":1282348800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/journals.iucr.org\/services\/copyrightpolicy.html"},{"start":{"date-parts":[[2010,8,21]],"date-time":"2010-08-21T00:00:00Z","timestamp":1282348800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.iucr.org\/services\/copyrightpolicy.html#TDM"}],"content-domain":{"domain":["iucr.org","wiley.com","iucrj.org"],"crossmark-restriction":true},"short-container-title":["Acta Crystallogr F Struct Biol Cryst Commun","Acta Cryst F","Acta Cryst Sect F","Acta Crystallogr F","Acta Crystallogr Sect F","Acta Cryst F Struct Biol Cryst Commun","Acta Cryst Sect F Struct Biol Cryst Commun"],"published-print":{"date-parts":[[2010,9,1]]},"abstract":"<jats:p><jats:italic>Burkholderia pseudomallei<\/jats:italic>, the causative agent of melioidosis, possesses a type III protein secretion apparatus that is similar to those found in<jats:italic>Salmonella<\/jats:italic>and<jats:italic>Shigella<\/jats:italic>. A major function of these secretion systems is to inject virulence-associated proteins into target cells of the host organism. The<jats:italic>bipD<\/jats:italic>gene of<jats:italic>B.\u00a0pseudomallei<\/jats:italic>encodes a secreted virulence factor that is similar in sequence and is most likely to be functionally analogous to IpaD from<jats:italic>Shigella<\/jats:italic>and SipD from<jats:italic>Salmonella<\/jats:italic>. Proteins in this family are thought to act as extracellular chaperones at the tip of the secretion needle to help the hydrophobic translocator proteins enter the target cell membrane, where they form a pore and may also link the translocon pore with the secretion needle. BipD has been crystallized in a monoclinic crystal form that diffracted X-rays to 1.5\u2005\u00c5 resolution and the structure was refined to an<jats:italic>R<\/jats:italic>factor of 16.1% and an<jats:italic>R<\/jats:italic><jats:sub>free<\/jats:sub>of 19.8% at this resolution. The putative dimer interface that was observed in previous crystal structures was retained and a larger surface area was buried in the new crystal form.<\/jats:p>","DOI":"10.1107\/s1744309110026333","type":"journal-article","created":{"date-parts":[[2010,8,20]],"date-time":"2010-08-20T16:23:22Z","timestamp":1282321402000},"page":"990-993","update-policy":"https:\/\/doi.org\/10.1107\/cm_01","source":"Crossref","is-referenced-by-count":8,"title":["Near-atomic resolution analysis of BipD, a component of the type III secretion system of<i>Burkholderia pseudomallei<\/i>"],"prefix":"10.1107","volume":"66","author":[{"given":"M.","family":"Pal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. T.","family":"Erskine","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. S.","family":"Gill","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. P.","family":"Wood","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. B.","family":"Cooper","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"329","published-online":{"date-parts":[[2010,8,21]]},"reference":[{"key":"fw5266_bb1","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1038\/434692a","volume":"434","author":"Aldhous","year":"2005","journal-title":"Nature (London)"},{"key":"fw5266_bb2","doi-asserted-by":"crossref","first-page":"3197","DOI":"10.1099\/00221287-147-12-3197","volume":"147","author":"Attree","year":"2001","journal-title":"Microbiology"},{"key":"fw5266_bb3","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1046\/j.1462-5822.2000.00068.x","volume":"2","author":"Blocker","year":"2000","journal-title":"Cell. Microbiol."},{"key":"fw5266_bb4","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1107\/S0907444994003112","volume":"50","author":"Collaborative Computational Project, Number 4","year":"1994","journal-title":"Acta Cryst. D"},{"key":"fw5266_bb5","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1097\/00001432-200204000-00005","volume":"15","author":"Dance","year":"2002","journal-title":"Curr. Opin. Infect. Dis."},{"key":"fw5266_bb6","doi-asserted-by":"crossref","first-page":"2126","DOI":"10.1107\/S0907444904019158","volume":"60","author":"Emsley","year":"2004","journal-title":"Acta Cryst. D"},{"key":"fw5266_bb7","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.jmb.2006.07.069","volume":"363","author":"Erskine","year":"2006","journal-title":"J. Mol. Biol."},{"key":"fw5266_bb8","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1110\/ps.062645007","volume":"16","author":"Espina","year":"2007","journal-title":"Protein Sci."},{"key":"fw5266_bb9","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1107\/S0907444905036693","volume":"62","author":"Evans","year":"2006","journal-title":"Acta Cryst. D"},{"key":"fw5266_bb10","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1107\/S0567739478001114","volume":"34","author":"French","year":"1978","journal-title":"Acta Cryst. A"},{"key":"fw5266_bb11","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1086\/497382","volume":"192","author":"Gan","year":"2005","journal-title":"J. Infect. Dis."},{"key":"fw5266_bb12","doi-asserted-by":"crossref","first-page":"14240","DOI":"10.1073\/pnas.0403302101","volume":"101","author":"Holden","year":"2004","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"fw5266_bb13","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1128\/MMBR.62.2.379-433.1998","volume":"62","author":"Hueck","year":"1998","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"fw5266_bb14","doi-asserted-by":"crossref","first-page":"4035","DOI":"10.1074\/jbc.M607945200","volume":"282","author":"Johnson","year":"2007","journal-title":"J. Biol. Chem."},{"key":"fw5266_bb15","doi-asserted-by":"crossref","first-page":"7078","DOI":"10.1128\/jb.177.24.7078-7085.1995","volume":"177","author":"Kaniga","year":"1995","journal-title":"J. Bacteriol."},{"key":"fw5266_bb16","doi-asserted-by":"crossref","first-page":"1865","DOI":"10.1110\/ps.0350503","volume":"12","author":"Kantardjieff","year":"2003","journal-title":"Protein Sci."},{"key":"fw5266_bb17","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1107\/S1744309106024857","volume":"62","author":"Knight","year":"2006","journal-title":"Acta Cryst. F"},{"key":"fw5266_bb18","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/j.jmb.2007.05.022","volume":"372","author":"Krissinel","year":"2007","journal-title":"J. Mol. Biol."},{"key":"fw5266_bb19","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1107\/S0907444905039107","volume":"62","author":"Leslie","year":"2006","journal-title":"Acta Cryst. D"},{"key":"fw5266_bb20","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/0022-2836(68)90205-2","volume":"33","author":"Matthews","year":"1968","journal-title":"J. Mol. Biol."},{"key":"fw5266_bb21","doi-asserted-by":"crossref","first-page":"271","DOI":"10.3201\/eid0204.960403","volume":"2","author":"Mecsas","year":"1996","journal-title":"Emerg. Infect. Dis."},{"key":"fw5266_bb22","doi-asserted-by":"crossref","first-page":"5293","DOI":"10.1002\/j.1460-2075.1994.tb06863.x","volume":"13","author":"M\u00e9nard","year":"1994","journal-title":"EMBO J."},{"key":"fw5266_bb23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.femsle.2005.08.036","volume":"252","author":"Mota","year":"2005","journal-title":"FEMS Microbiol. Lett."},{"key":"fw5266_bb24","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.sbi.2007.12.011","volume":"18","author":"Moraes","year":"2008","journal-title":"Curr. Opin. Struct. Biol."},{"key":"fw5266_bb25","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1107\/S0907444996012255","volume":"53","author":"Murshudov","year":"1997","journal-title":"Acta Cryst. D"},{"key":"fw5266_bb26","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1126\/science.273.5279.1231","volume":"273","author":"Pettersson","year":"1996","journal-title":"Science"},{"key":"fw5266_bb27","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1099\/0022-1317-51-5-374","volume":"51","author":"Rainbow","year":"2002","journal-title":"J. Med. Microbiol."},{"key":"fw5266_bb28","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1107\/S0907444901012471","volume":"57","author":"Read","year":"2001","journal-title":"Acta Cryst. D"},{"key":"fw5266_bb29","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1107\/S1744309106027035","volume":"62","author":"Roversi","year":"2006","journal-title":"Acta Cryst. F"},{"key":"fw5266_bb30","doi-asserted-by":"crossref","first-page":"2669","DOI":"10.1099\/mic.0.27146-0","volume":"150","author":"Stevens","year":"2004","journal-title":"Microbiology"},{"key":"fw5266_bb31","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1046\/j.1365-2958.2002.03190.x","volume":"46","author":"Stevens","year":"2002","journal-title":"Mol. Microbiol."},{"key":"fw5266_bb33","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.tibs.2006.02.005","volume":"31","author":"Yip","year":"2006","journal-title":"Trends Biochem. Sci."}],"container-title":["Acta Crystallographica Section F Structural Biology and Crystallization Communications"],"original-title":[],"link":[{"URL":"http:\/\/journals.iucr.org\/f\/issues\/2010\/09\/00\/fw5266\/fw5266.pdf","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.iucr.org\/f\/issues\/2010\/09\/00\/fw5266\/fw5266.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,11]],"date-time":"2025-01-11T14:51:39Z","timestamp":1736607099000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.iucr.org\/paper?S1744309110026333"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,8,21]]},"references-count":32,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2010,9]]}},"alternative-id":["S1744309110026333"],"URL":"https:\/\/doi.org\/10.1107\/s1744309110026333","relation":{},"ISSN":["1744-3091"],"issn-type":[{"type":"electronic","value":"1744-3091"}],"subject":[],"published":{"date-parts":[[2010,8,21]]},"assertion":[{"value":"Acta Crystallographica Section F: Structural Biology and Crystallization Communications","order":0,"name":"journal","label":"Publication","explanation":{"URL":"http:\/\/journals.iucr.org\/f"},"group":{"name":"general","label":"General"}},{"value":"structural communications","order":1,"name":"content_type","label":"Content type","explanation":{"URL":"http:\/\/journals.iucr.org\/f\/services\/notesforauthors.html"},"group":{"name":"general","label":"General"}},{"value":"Available","URL":"http:\/\/scripts.iucr.org\/cgi-bin\/citedin?fw5266","order":2,"name":"article_metrics","label":"Article metrics","group":{"name":"general","label":"General"}},{"value":"Yes","order":0,"name":"peer_reviewed","label":"Peer reviewed","group":{"name":"peer_review","label":"Peer review"}},{"value":"Single blind","order":1,"name":"review_process","label":"Review process","group":{"name":"peer_review","label":"Peer review"}},{"value":"10 June 2010","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication history"}},{"value":"3 July 2010","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication history"}},{"value":"21 August 2010","order":2,"name":"published_online","label":"Published online","group":{"name":"publication_history","label":"Publication history"}},{"value":"This article has supporting information","name":"supplementary_materials","label":"Supplementary materials","explanation":{"URL":"http:\/\/scripts.iucr.org\/cgi-bin\/sendsup?fw5266"}},{"value":"\u00a9 2010 International Union of Crystallography","order":0,"name":"copyright","label":"Copyright","explanation":{"URL":"http:\/\/journals.iucr.org\/services\/copyrightpolicy.html"},"group":{"name":"copyright_and_licensing","label":"Copyright and licencing"}}]}}