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The products have been fully characterized by elemental analysis, IR and NMR spectroscopy, mass spectrometry and crystal structure analysis. In (1\u2032<jats:italic>RS<\/jats:italic>,2\u2032<jats:italic>RS<\/jats:italic>,3<jats:italic>SR<\/jats:italic>,7a\u2032<jats:italic>SR<\/jats:italic>)-2\u2032-benzoyl-1-hexyl-2-oxo-1\u2032,2\u2032,5\u2032,6\u2032,7\u2032,7a\u2032-hexahydrospiro[indoline-3,3\u2032-pyrrolizine]-1\u2032-carboxylic acid, C<jats:sub>28<\/jats:sub>H<jats:sub>32<\/jats:sub>N<jats:sub>2<\/jats:sub>O<jats:sub>4<\/jats:sub>, (I), the unsubstituted pyrrole ring and the reduced spiro-fused pyrrole ring adopt half-chair and envelope conformations, respectively, while in (1\u2032<jats:italic>RS<\/jats:italic>,2\u2032<jats:italic>RS<\/jats:italic>,3<jats:italic>SR<\/jats:italic>,7a\u2032<jats:italic>SR<\/jats:italic>)-1\u2032,2\u2032-bis(4-chlorobenzoyl)-5,7-dichloro-2-oxo-1\u2032,2\u2032,5\u2032,6\u2032,7\u2032,7a\u2032-hexahydrospiro[indoline-3,3\u2032-pyrrolizine], which crystallizes as a partial dichloromethane solvate, C<jats:sub>28<\/jats:sub>H<jats:sub>20<\/jats:sub>Cl<jats:sub>4<\/jats:sub>N<jats:sub>2<\/jats:sub>O<jats:sub>3<\/jats:sub>\u00b70.981CH<jats:sub>2<\/jats:sub>Cl<jats:sub>2<\/jats:sub>, (II), where the solvent component is disordered over three sets of atomic sites, these two rings adopt envelope and half-chair conformations, respectively. Molecules of (I) are linked by an O\u2014H...\u00b7O hydrogen bond to form cyclic <jats:italic>R<\/jats:italic>\n                  <jats:sub>6<\/jats:sub>\n                  <jats:sup>6<\/jats:sup>(48) hexamers of \\overline{3} (<jats:italic>S<\/jats:italic>\n                  <jats:sub>6<\/jats:sub>) symmetry, which are further linked by two C\u2014H...O hydrogen bonds to form a three-dimensional framework structure. In compound (II), inversion-related pairs of N\u2014H...O hydrogen bonds link the spiro[indoline-3,3\u2032-pyrrolizine] molecules into simple <jats:italic>R<\/jats:italic>\n                  <jats:sub>2<\/jats:sub>\n                  <jats:sup>2<\/jats:sup>(8) dimers.<\/jats:p>","DOI":"10.1107\/s2053229617016072","type":"journal-article","created":{"date-parts":[[2017,11,13]],"date-time":"2017-11-13T16:47:05Z","timestamp":1510591625000},"page":"1109-1115","update-policy":"https:\/\/doi.org\/10.1107\/cm_01","source":"Crossref","is-referenced-by-count":8,"title":["Synthesis of spiro[indoline-3,3\u2032-pyrrolizines] by 1,3-dipolar reactions between isatins, <scp>L<\/scp>-proline and electron-deficient alkenes"],"prefix":"10.1107","volume":"73","author":[{"given":"Jairo","family":"Quiroga","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pablo","family":"Romo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9184-2390","authenticated-orcid":true,"given":"Justo","family":"Cobo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher","family":"Glidewell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"329","published-online":{"date-parts":[[2017,11,13]]},"reference":[{"key":"sk3676_bb1","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.bmc.2013.11.040","volume":"22","author":"Belal","year":"2014","journal-title":"Bioorg. 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