{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T21:21:58Z","timestamp":1740172918282,"version":"3.37.3"},"reference-count":29,"publisher":"International Union of Crystallography (IUCr)","issue":"12","license":[{"start":{"date-parts":[[2021,11,5]],"date-time":"2021-11-05T00:00:00Z","timestamp":1636070400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/journals.iucr.org\/services\/copyrightpolicy.html"},{"start":{"date-parts":[[2021,11,5]],"date-time":"2021-11-05T00:00:00Z","timestamp":1636070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.iucr.org\/services\/copyrightpolicy.html#TDM"}],"funder":[{"DOI":"10.13039\/501100004281","name":"Narodowe Centrum Nauki","doi-asserted-by":"crossref","award":["UMO-2016\/21\/B\/ST5\/00100"],"award-info":[{"award-number":["UMO-2016\/21\/B\/ST5\/00100"]}],"id":[{"id":"10.13039\/501100004281","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["iucr.org","wiley.com","iucrj.org"],"crossmark-restriction":true},"short-container-title":["Acta Crystallogr C Struct Chem","Acta Crystallogr C","Acta Crystallogr C Cryst Struct Commun","Acta Cryst C","Acta Cryst C Struct Chem","Acta Cryst Sect C","Acta Cryst Sect C Struct Chem","Acta Crystallogr Sect C","Acta Crystallogr Sect C Struct Chem","Acta Crystallogr Sect C Cryst Struct Commun"],"accepted":{"date-parts":[[2021,10,22]]},"published-print":{"date-parts":[[2021,12,1]]},"abstract":"<jats:p>The structure of <jats:italic>N<\/jats:italic>-triphenylacetyl-L-tyrosine (C<jats:sub>29<\/jats:sub>H<jats:sub>25<\/jats:sub>NO<jats:sub>4<\/jats:sub>, L-<jats:bold>TrCOTyr<\/jats:bold>) is characterized by the presence of both donors and acceptors of classical hydrogen bonds. At the same time, the molecule contains a sterically demanding and hydrophobic trityl group capable of participating in \u03c0-electron interactions. Due to its large volume, the trityl group may favour the formation of structural voids in the crystals, which can be filled with guest molecules. In this article, we present the crystal structures of a series of <jats:italic>N<\/jats:italic>-triphenylacetyl-L-tyrosine solvates with chloroform, namely, L-<jats:bold>TrCOTyr<\/jats:bold>\u00b7CHCl<jats:sub>3<\/jats:sub> (<jats:bold>I<\/jats:bold>) and L-<jats:bold>TrCOTyr<\/jats:bold>\u00b71.5CHCl<jats:sub>3<\/jats:sub> (<jats:bold>III<\/jats:bold>), and dichloromethane, namely, L-<jats:bold>TrCOTyr<\/jats:bold>\u00b7CH<jats:sub>2<\/jats:sub>Cl<jats:sub>2<\/jats:sub> (<jats:bold>II<\/jats:bold>) and L-<jats:bold>TrCOTyr<\/jats:bold>\u00b70.1CH<jats:sub>2<\/jats:sub>Cl<jats:sub>2<\/jats:sub> (<jats:bold>IV<\/jats:bold>). To complement the topic, we also decided to use the racemic amide <jats:italic>N<\/jats:italic>-triphenylacetyl-DL-tyrosine (<jats:italic>rac<\/jats:italic>-<jats:bold>TrCOTyr<\/jats:bold>) and recrystallized it from a mixture of chloroform and dichloromethane. As a result, <jats:italic>rac<\/jats:italic>-<jats:bold>TrCOTyr<\/jats:bold>\u00b71.5CHCl<jats:sub>3<\/jats:sub> (<jats:bold>V<\/jats:bold>) was obtained. In the crystal structures, the amide molecules interact with each other <jats:italic>via<\/jats:italic> O\u2014H...O hydrogen bonds. Noticeably, the amide N\u2014H group does not participate in the formation of intermolecular hydrogen bonds. Channels are formed between the <jats:bold>TrCOTyr<\/jats:bold> molecules and these are filled with solvent molecules. Additionally, in the crystals of <jats:bold>III<\/jats:bold> and <jats:bold>V<\/jats:bold>, there are structural voids that are occupied by chloroform molecules. Structure analysis has shown that solvates <jats:bold>I<\/jats:bold> and <jats:bold>II<\/jats:bold> are isostructural. Upon loss of solvent, the solvates transform into the solvent-free form of <jats:bold>TrCOTyr<\/jats:bold>, as confirmed by thermogravimetric analysis, differential scanning calorimetry and powder X-ray diffraction.<\/jats:p>","DOI":"10.1107\/s2053229621011098","type":"journal-article","created":{"date-parts":[[2021,11,5]],"date-time":"2021-11-05T14:13:06Z","timestamp":1636121586000},"page":"745-756","update-policy":"https:\/\/doi.org\/10.1107\/cm_01","source":"Crossref","is-referenced-by-count":0,"title":["Diversity of <i>N<\/i>-triphenylacetyl-<scp>L<\/scp>-tyrosine solvates with halogenated solvents"],"prefix":"10.1107","volume":"77","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6078-8782","authenticated-orcid":true,"given":"Agnieszka","family":"Czapik","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcin","family":"Kwit","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"329","published-online":{"date-parts":[[2021,11,5]]},"reference":[{"key":"ef3022_bb1","doi-asserted-by":"crossref","unstructured":"Akazome, M. 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