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The formyl intermediates and the hybrid products have all been fully characterized using a combination of IR, <jats:sup>1<\/jats:sup>H and <jats:sup>13<\/jats:sup>C NMR spectroscopy, and high-resolution mass spectrometry, and the structures of the three hybrid products have been determined using single-crystal X-ray diffraction. Ethyl (<jats:italic>E<\/jats:italic>)-2-(1<jats:italic>H<\/jats:italic>-benzo[<jats:italic>d<\/jats:italic>]imidazol-2-yl)-4-(4-chlorostyryl)quinoline-3-carboxylate, C<jats:sub>27<\/jats:sub>H<jats:sub>20<\/jats:sub>ClN<jats:sub>3<\/jats:sub>O<jats:sub>2<\/jats:sub>, (IIIa), and ethyl (<jats:italic>E<\/jats:italic>)-2-(1<jats:italic>H<\/jats:italic>-benzo[<jats:italic>d<\/jats:italic>]imidazol-2-yl)-4-(2-methoxystyryl)quinoline-3-carboxylate, C<jats:sub>28<\/jats:sub>H<jats:sub>23<\/jats:sub>N<jats:sub>3<\/jats:sub>O<jats:sub>3<\/jats:sub>, (IIIb), both crystallize in the solvent-free form with <jats:italic>Z<\/jats:italic>\u2032\u00a0= 1, but ethyl (<jats:italic>E<\/jats:italic>)-2-(1<jats:italic>H<\/jats:italic>-benzo[<jats:italic>d<\/jats:italic>]imidazol-2-yl)-4-(4-methylstyryl)quinoline-3-carboxylate, C<jats:sub>28<\/jats:sub>H<jats:sub>23<\/jats:sub>N<jats:sub>3<\/jats:sub>O<jats:sub>2<\/jats:sub>, (IIIc), crystallizes as a partial hexane solvate with <jats:italic>Z<\/jats:italic>\u2032\u00a0= 3, and the ester group in one of the independent molecules is disordered over two sets of atomic sites having occupancies of 0.765\u2005(7) and 0.235\u2005(7). The molecules of (IIIc) enclose continuous channels which are occupied by disordered solvent molecules having partial occupancy. In all of the molecules of (IIIa)\u2013(IIIc), the styrylquinoline fragment is markedly nonplanar. Different combinations of N\u2014H...O and C\u2014H...\u03c0 hydrogen bonds generate supramolecular assemblies which are two-dimensional in (IIIb) and (IIIc), but three-dimensional in (IIIa). Comparisons are made with the structures of some related compounds.<\/jats:p>","DOI":"10.1107\/s2053229622010063","type":"journal-article","created":{"date-parts":[[2022,10,25]],"date-time":"2022-10-25T17:04:09Z","timestamp":1666717449000},"page":"671-680","update-policy":"https:\/\/doi.org\/10.1107\/cm_01","source":"Crossref","is-referenced-by-count":4,"title":["Synthesis, and spectroscopic and structural characterization of three new styrylquinoline\u2013benzimidazole hybrids"],"prefix":"10.1107","volume":"78","author":[{"given":"Diana M.","family":"Ardila","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diego F.","family":"Rodr\u00edguez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alirio","family":"Palma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7077-9772","authenticated-orcid":true,"given":"Iv\u00e1n","family":"D\u00edaz Costa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9184-2390","authenticated-orcid":true,"given":"Justo","family":"Cobo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7621-7538","authenticated-orcid":true,"given":"Christopher","family":"Glidewell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"329","published-online":{"date-parts":[[2022,10,25]]},"reference":[{"key":"ky3223_bb1","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1016\/j.ejmech.2014.07.044","volume":"97","author":"Afzal","year":"2015","journal-title":"Eur. 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